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Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, 卷号: 17, 期号: 11, 页码: 2703-2717
作者:  Wei,Ruiran;  Zhao,Yueqin;  Wang,Juan;  Yang,Xu;  Li,Shunlin;  Wang,Yinyuan;  Yang,Xingzhi;  Fei,Jimin;  Hao,Xiaojiang;  Zhao,Yuhan;  Gui,Liming;  Ding,Xiao
浏览  |  Adobe PDF(9123Kb)  |  收藏  |  浏览/下载：148/30  |  提交时间：2022/04/02
Ferroptosis  Tagitinin c  Ros  Er Stress  Nrf2-ho-1 Pathway  Endoplasmic-reticulum Stress  Er-stress  Oxidative Stress  Tumor-suppressor  Nrf2  Death  Iron  Differentiation  Mechanisms  Resistance  
Cytotoxic phenolic constituents from Hypericum japonicum 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 33-40
作者:  Zhu, Wei;  Qiu, Jie;  Zeng, Yan-Rong;  Yi, Ping;  Lou, Hua-Yong;  Jian, Jun-You;  Zuo, Ming-Xing;  Duan, Lian;  Gu, Wei;  Huang, Lie-Jun;  Li, Yan-Mei;  Yuan, Chun-Mao;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(902Kb)  |  收藏  |  浏览/下载：450/199  |  提交时间：2019/09/10
Hypericum japonicum thunb. (Hypericaceae)  Phenolic compounds  Xanthone and flavonoid derivatives  Cytotoxic activities  Structure-activity relationship  
Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 7, 页码: 10
作者:  Zhang, Yu;  Goto, Masuo;  Oda, Akifumi;  Hsu, Pei-Ling;  Guo, Ling-Li;  Fu, Yan-Hui;  Morris-Natschke, Susan L.;  Hamel, Ernest;  Lee, Kuo-Hsiung;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3129Kb)  |  收藏  |  浏览/下载：292/32  |  提交时间：2019/07/29
aspidosperma-type  monoterpenoid indole alkaloids  antiproliferative activity  tubulin inhibitor  Bousigonia mekongensis  
Design, Synthesis, and Structural Optimization of Lycorine-Derived Phenanthridine Derivatives as Wnt/beta-Catenin Signaling Pathway Agonists 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 1, 页码: 180-188
作者:  Chen, Duo-Zhi;  Jing, Chen-Xu;  Cai, Jie-Yun;  Wu, Ji-Bo;  Wang, Sheng;  Yin, Jun -Lin;  Li, Xiao-Nian;  Li, Lin;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3043Kb)  |  收藏  |  浏览/下载：356/81  |  提交时间：2016/06/27
Cytotoxic indole alkaloids from the fruits of Melodinus cochinchinensis 期刊论文
PHYTOCHEMISTRY, 2015, 卷号: 116, 页码: 367-373
作者:  Shao, Shun;  Zhang, Hao;  Yuan, Chun-Mao;  Zhang, Yu;  Cao, Ming-Ming;  Zhang, Hai-Yuan;  Feng, Yan;  Ding, Xiao;  Zhou, Qiang;  Zhao, Qing;  He, Hong-Ping;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(570Kb)  |  收藏  |  浏览/下载：688/390  |  提交时间：2015/12/17
Melodinus Cochinchinensis  Apocynaceae  Indole Alkaloids  Cytotoxicity  
A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2013, 卷号: 63, 期号: SI, 页码: 485-494
作者:  Liu, Jinhua;  Mu, Chenglong;  Yue, Wen;  Li, Jie;  Ma, Biao;  Zhao, Lixia;  Liu, Lei;  Chen, Quan;  Yan, Chen;  Liu, Haiyang;  Hao, Xiaojiang;  Zhu, Yushan
浏览  |  Adobe PDF(2679Kb)  |  收藏  |  浏览/下载：345/66  |  提交时间：2013/10/16
Thioredoxin Reductase  Bim  Ros  Apoptosis  Cancer  
Shizukaol D Isolated from Chloranthus japonicas Inhibits AMPK-Dependent Lipid Content in Hepatic Cells by Inducing Mitochondrial Dysfunction 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 8, 页码: e73527
作者:  Hu, Rongkuan;  Yan, Huan;  Hao, Xiaojiang;  Liu, Haiyang;  Wu, Jiarui
浏览  |  Adobe PDF(1041Kb)  |  收藏  |  浏览/下载：597/88  |  提交时间：2013/10/16
Activated Protein-kinase  Fatty-acid Oxidation  Respiratory Complex-i  Insulin-resistance  Malonyl-coa  Signaling Pathways  Glucose-uptake  L6 Myotubes  Hepg2 Cells  Metformin  
Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes 期刊论文
PHYTOCHEMISTRY LETTERS, 2013, 卷号: 6, 期号: 3, 页码: 368-371
作者:  Qiu, Lu;  Liang, Yan;  Tang, Gui-Hua;  Yuan, Chun-Mao;  Zhang, Yu;  Hao, Xiao-Yan;  Hao, Xiao-Jiang;  He, Hong-Ping
浏览  |  Adobe PDF(290Kb)  |  收藏  |  浏览/下载：481/141  |  提交时间：2013/10/16
Indigofera Stachyodes  Flavonol  Flavan Dimer  Hepatoprotective Effect  
The endoperoxide ascaridol shows strong differential cytotoxicity in nucleotide excision repair-deficient cells 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 卷号: 259, 期号: 3, 页码: 302-310
作者:  Abbasi, Rashda;  Efferth, Thomas;  Kuhmann, Christine;  Opatz, Till;  Hao, Xiaojiang;  Popanda, Odilia;  Schmezer, Peter
Adobe PDF(738Kb)  |  收藏  |  浏览/下载：504/171  |  提交时间：2012/06/07
Cancer Therapy  Synthetic Lethal  Traditional Chinese Medicine  Xpc  Ercc6  Csb  
Cytotoxic cycloartanes from the fruits of Caloncoba glauca 期刊论文
PHYTOCHEMISTRY LETTERS, 2012, 卷号: 5, 期号: 1, 页码: 183-187
作者:  Mpetga, James D. Simo;  Tene, Mathieu;  Wabo, Hippolyte K.;  Li, Shi-Fei;  Kong, Ling-Mei;  He, Hong-Ping;  Hao, Xiao-Jiang;  Tane, Pierre
Adobe PDF(232Kb)  |  收藏  |  浏览/下载：434/200  |  提交时间：2012/06/07
Cycloartane  Glaucartanoic Acid  Caloncoba Glauca  Cytotoxicity