Cytotoxic indole alkaloids from the fruits of Melodinus cochinchinensis
Shao, Shun; Zhang, Hao; Yuan, Chun-Mao; Zhang, Yu; Cao, Ming-Ming; Zhang, Hai-Yuan; Feng, Yan; Ding, Xiao; Zhou, Qiang; Zhao, Qing; He, Hong-Ping; Hao, Xiao-Jiang
2015-08-01
Source PublicationPHYTOCHEMISTRY
Volume116Pages:367-373
AbstractEight indole alkaloids, melosines A-H, together with 13 known alkaloids, were isolated from the fruits of Melodinus cochinchinensis. The structure elucidation of isolated secondary metabolites was based on comprehensive spectroscopic data analysis. Melosine B showed moderate cytotoxic activity against five human cancer cell lines, HL-60, SMMC-7721, A-549, MCF-7, and SW480 with IC50 values ranging from 1.6 to 8.1 mu M. (C) 2015 Elsevier Ltd. All rights reserved.
KeywordMelodinus Cochinchinensis Apocynaceae Indole Alkaloids Cytotoxicity
DOI10.1016/j.phytochem.2015.02.028
Indexed BySCI
Language英语
WOS IDWOS:000357438200041
Citation statistics
Cited Times:20[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/24983
Collection植物化学与西部植物资源持续利用国家重点实验室
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GB/T 7714
Shao, Shun,Zhang, Hao,Yuan, Chun-Mao,et al. Cytotoxic indole alkaloids from the fruits of Melodinus cochinchinensis[J]. PHYTOCHEMISTRY,2015,116:367-373.
APA Shao, Shun.,Zhang, Hao.,Yuan, Chun-Mao.,Zhang, Yu.,Cao, Ming-Ming.,...&Hao, Xiao-Jiang.(2015).Cytotoxic indole alkaloids from the fruits of Melodinus cochinchinensis.PHYTOCHEMISTRY,116,367-373.
MLA Shao, Shun,et al."Cytotoxic indole alkaloids from the fruits of Melodinus cochinchinensis".PHYTOCHEMISTRY 116(2015):367-373.
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