| Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes | |
Qiu, Lu1,2; Liang, Yan1; Tang, Gui-Hua2 ; Yuan, Chun-Mao2; Zhang, Yu2; Hao, Xiao-Yan1; Hao, Xiao-Jiang2; He, Hong-Ping2
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| Corresponding Author | Hao, XY (reprint author), Guiyang Med Coll, Sch Pharm, Guiyang 550004, Guizhou, Peoples R China. ; haoxiaoyan@vip.163.com ; hehongping@mail.kib.ac.cn |
| 2013-08-01 | |
| Source Publication | PHYTOCHEMISTRY LETTERS
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| ISSN | 1874-3900 |
| Volume | 6Issue:3Pages:368-371 |
| Abstract | A new flavan dimer, 2 alpha,3 alpha-epoxyflavan-5,7,3',4'-tetraol-(4 beta -> 8)-flavan-5 '',7 '',4'''-triol (1), and a new flavonol, 3-O-(3-nitropropanoyl)-2,3-cis-5,7,3',4'-tetrahydroxyflavan (2), together with a known compound, 2 alpha,3 alpha-epoxy-5,7,3',4'-tetrahydroxyflavan-(4 beta -> 8)-epicatechin (3), were isolated from the roots of Indigofera stachyodes. Their structures were elucidated by spectroscopic techniques including MS, 1D NMR, and 2D NMR. Compounds 2 and 3 were evaluated to determine their protective effects against carbon tetrachloride (CCl4)-induced hepatotoxicity in the human liver cell line HL-7702. The results showed that 2 and 3 could protect HL-7702 cells from injury induced by CCl4, with cell survival rates of 122.0% and 72.5%, respectively. (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved. |
| Keyword | Indigofera Stachyodes Flavonol Flavan Dimer Hepatoprotective Effect |
| Subject Area | Biochemistry & Molecular Biology ; Plant Sciences |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000322312900013 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/16725 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Guiyang Med Coll, Sch Pharm, Guiyang 550004, Guizhou, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resource West Chi, Kunming 650201, Yunnan, Peoples R China |
| Recommended Citation GB/T 7714 | Qiu, Lu,Liang, Yan,Tang, Gui-Hua,et al. Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes[J]. PHYTOCHEMISTRY LETTERS,2013,6(3):368-371. |
| APA | Qiu, Lu.,Liang, Yan.,Tang, Gui-Hua.,Yuan, Chun-Mao.,Zhang, Yu.,...&He, Hong-Ping.(2013).Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes.PHYTOCHEMISTRY LETTERS,6(3),368-371. |
| MLA | Qiu, Lu,et al."Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes".PHYTOCHEMISTRY LETTERS 6.3(2013):368-371. |
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