Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes

	Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes
	Qiu, Lu 1,2; Liang, Yan 1; Tang, Gui-Hua2 ; Yuan, Chun-Mao 2; Zhang, Yu2 ; Hao, Xiao-Yan 1; Hao, Xiao-Jiang2 ; He, Hong-Ping 2
通讯作者	Hao, XY (reprint author), Guiyang Med Coll, Sch Pharm, Guiyang 550004, Guizhou, Peoples R China. ; haoxiaoyan@vip.163.com ; hehongping@mail.kib.ac.cn
	2013-08-01
发表期刊	PHYTOCHEMISTRY LETTERS
ISSN	1874-3900
卷号	6 期号:3 页码:368-371
摘要	A new flavan dimer, 2 alpha,3 alpha-epoxyflavan-5,7,3',4'-tetraol-(4 beta -> 8)-flavan-5 '',7 '',4'''-triol (1), and a new flavonol, 3-O-(3-nitropropanoyl)-2,3-cis-5,7,3',4'-tetrahydroxyflavan (2), together with a known compound, 2 alpha,3 alpha-epoxy-5,7,3',4'-tetrahydroxyflavan-(4 beta -> 8)-epicatechin (3), were isolated from the roots of Indigofera stachyodes. Their structures were elucidated by spectroscopic techniques including MS, 1D NMR, and 2D NMR. Compounds 2 and 3 were evaluated to determine their protective effects against carbon tetrachloride (CCl4)-induced hepatotoxicity in the human liver cell line HL-7702. The results showed that 2 and 3 could protect HL-7702 cells from injury induced by CCl4, with cell survival rates of 122.0% and 72.5%, respectively. (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
关键词	Indigofera Stachyodes Flavonol Flavan Dimer Hepatoprotective Effect
学科领域	Biochemistry & Molecular Biology ; Plant Sciences
收录类别	SCI
语种	英语
WOS记录号	WOS:000322312900013
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/16725
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Guiyang Med Coll, Sch Pharm, Guiyang 550004, Guizhou, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resource West Chi, Kunming 650201, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Qiu, Lu,Liang, Yan,Tang, Gui-Hua,et al. Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes[J]. PHYTOCHEMISTRY LETTERS,2013,6(3):368-371.
APA	Qiu, Lu.,Liang, Yan.,Tang, Gui-Hua.,Yuan, Chun-Mao.,Zhang, Yu.,...&He, Hong-Ping.(2013).Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes.PHYTOCHEMISTRY LETTERS,6(3),368-371.
MLA	Qiu, Lu,et al."Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes".PHYTOCHEMISTRY LETTERS 6.3(2013):368-371.

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