Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes
Qiu, Lu1,2; Liang, Yan1; Tang, Gui-Hua2; Yuan, Chun-Mao2; Zhang, Yu2; Hao, Xiao-Yan1; Hao, Xiao-Jiang2; He, Hong-Ping2
2013-08-01
发表期刊PHYTOCHEMISTRY LETTERS
ISSN1874-3900
卷号6期号:3页码:368-371
摘要A new flavan dimer, 2 alpha,3 alpha-epoxyflavan-5,7,3',4'-tetraol-(4 beta -> 8)-flavan-5 '',7 '',4'''-triol (1), and a new flavonol, 3-O-(3-nitropropanoyl)-2,3-cis-5,7,3',4'-tetrahydroxyflavan (2), together with a known compound, 2 alpha,3 alpha-epoxy-5,7,3',4'-tetrahydroxyflavan-(4 beta -> 8)-epicatechin (3), were isolated from the roots of Indigofera stachyodes. Their structures were elucidated by spectroscopic techniques including MS, 1D NMR, and 2D NMR. Compounds 2 and 3 were evaluated to determine their protective effects against carbon tetrachloride (CCl4)-induced hepatotoxicity in the human liver cell line HL-7702. The results showed that 2 and 3 could protect HL-7702 cells from injury induced by CCl4, with cell survival rates of 122.0% and 72.5%, respectively. (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
关键词Indigofera Stachyodes Flavonol Flavan Dimer Hepatoprotective Effect
资助信息special project of Guizhou on the modernization of traditional Chinese medicine and research and development of science and technology industry [20105005]; science and technology foundation of Guizhou [20112286]; Young Academic and Technical Leader Raising Foundation of Yunnan Province [2010CI047]
收录类别SCI
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/16725
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Guiyang Med Coll, Sch Pharm, Guiyang 550004, Guizhou, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resource West Chi, Kunming 650201, Yunnan, Peoples R China
推荐引用方式
GB/T 7714
Qiu, Lu,Liang, Yan,Tang, Gui-Hua,et al. Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes[J]. PHYTOCHEMISTRY LETTERS,2013,6(3):368-371.
APA Qiu, Lu.,Liang, Yan.,Tang, Gui-Hua.,Yuan, Chun-Mao.,Zhang, Yu.,...&He, Hong-Ping.(2013).Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes.PHYTOCHEMISTRY LETTERS,6(3),368-371.
MLA Qiu, Lu,et al."Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes".PHYTOCHEMISTRY LETTERS 6.3(2013):368-371.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Qiu-2013-Two new fla(290KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Qiu, Lu]的文章
[Liang, Yan]的文章
[Tang, Gui-Hua]的文章
百度学术
百度学术中相似的文章
[Qiu, Lu]的文章
[Liang, Yan]的文章
[Tang, Gui-Hua]的文章
必应学术
必应学术中相似的文章
[Qiu, Lu]的文章
[Liang, Yan]的文章
[Tang, Gui-Hua]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。