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Inverse Electron-Demanding Diels-Alder Reactions in the Chemical Synthesis of Prenylated Indole Alkaloids Containing a Bicycle[2.2.2]diazaoctane Moiety: A Theoretical Study 期刊论文
CHEMISTRY-AN ASIAN JOURNAL, 2023, 卷号: 18, 期号: 7
作者:  Xu,Wenqiang;  Sun,Tian-Yu;  Di,Yingtong;  Hao,Xiaojiang;  Wu,Yun-Dong
浏览  |  Adobe PDF(8430Kb)  |  收藏  |  浏览/下载：35/10  |  提交时间：2024/07/10
alkaloids  chemical synthesis  inverse-electron demanding Diels-Alder reaction  reaction mechanisms  theoretical study  BIOMIMETIC TOTAL-SYNTHESIS  CORRELATED MOLECULAR CALCULATIONS  MARINE-DERIVED FUNGUS  GAUSSIAN-BASIS SETS  (-)-VERSICOLAMIDE B  ORBITAL METHODS  BREVIANAMIDE-A  STEPHACIDIN-A  MODEL  CONCISE  
Chemical Constituents of Primulina eburnea (Gesneriaceae) and Their Cytotoxic Activities 期刊论文
CHEMISTRY & BIODIVERSITY, 2023
作者:  Yang,Li-Yuan;  Yi,Ping;  Chen,Jun-Lei;  Li,Yu-Huan;  Qiu,Jue-Lin;  Wang,Zhao-Yang;  Fu,Mao;  Yuan,Chun-Mao;  Huang,Lie-Jun;  Hao,Xiao-Jiang;  Gu,Wei
Adobe PDF(1860Kb)  |  收藏  |  浏览/下载：38/12  |  提交时间：2024/07/10
Primulina eburnea  triterpenes  flavonoids  phenylethanoid glycosides  cytotoxic activity  GLUCOSIDES  LEAVES  CELL  
Constituents from Zanthoxylum dimorphophyllum and their chemotaxonomic significance 期刊论文
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2023, 卷号: 108, 页码: 104640
作者:  Wang,Zhaoyang;  Yuan,Chunmao;  Chen,Junlei;  Li,Yuhuan;  Wei,Yinghuan;  Li,Huanyang;  Qiu,Juelin;  Huang,Liejun;  Hu,Zhanxing;  Hao,Xiaojiang;  Gu,Wei
浏览  |  Adobe PDF(847Kb)  |  收藏  |  浏览/下载：25/7  |  提交时间：2024/07/22
Chemotaxonomic significance  Zanthoxylum dimorphophyllum  Rutaceae  Coumarins  Lignans  Alkaloids  CHEMICAL-CONSTITUENTS  ANTIINFLAMMATORY CONSTITUENTS  ANTIPLATELET CONSTITUENTS  AERIAL PARTS  ROOT BARK  COUMARINS  DERIVATIVES  
A flavonolignan, flavonoids and alkylamides from the fruits of Zanthoxylum Motuoense Huang 期刊论文
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2023, 卷号: 109, 页码: 104659
作者:  Wei,Yinghuan;  Chen,Junlei;  Qiu,Juelin;  Wang,Zhaoyang;  Li,Huanyang;  Yang,Jue;  Huang,Liejun;  Yuan,Chunmao;  Hao,Xiaojiang;  Gu,Wei
浏览  |  Adobe PDF(937Kb)  |  收藏  |  浏览/下载：29/11  |  提交时间：2024/07/22
Zanthoxylum motuoense Huang  Flavonolignan  Alkylamides  Neuroprotective activity  Chemotaxonomy  ALIPHATIC ACID-AMIDES  
Bioassay-guided isolation of α-Glucosidase inhibitory constituents from Hypericum sampsonii 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2023, 卷号: 21, 期号: 6, 页码: 443-453
作者:  Tao,Linlan;  Xu,Shuangyu;  Zhang,Zizhen;  Li,Yanan;  Yang,Jue;  Gu,Wei;  Yi,Ping;  Hao,Xiaojiang;  Yuan,Chunmao
浏览  |  Adobe PDF(1033Kb)  |  收藏  |  浏览/下载：29/12  |  提交时间：2024/07/22
Hypericum sampsonii  Chemical constituents  Structure elucidation  alpha-Glucosidase  Molecular docking  POLYCYCLIC POLYPRENYLATED ACYLPHLOROGLUCINOLS  POTENT INHIBITORS  SPECTROSCOPY  DERIVATIVES  CHEMISTRY  AMYLASE  ROOTS  
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction 期刊论文
NATURE CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 4, 页码: 468-+
作者:  Guo,Yingjie;  Zhang,Huan;  Yan,Chen;  Shen,Birong;  Zhang,Yue;  Guo,Xiangyang;  Sun,Sha;  Yu,Fan;  Yan,Jiayun;  Liu,Ronghe;  Zhang,Qianping;  Zhang,Di;  Liu,Haiyang;  Liu,Yang;  Zhang,Yaoyao;  Li,Wenlei;  Qin,Jiangyu;  Lv,He;  Wang,Zhaoxia;  Yuan,Yun;  Yang,Jie-Feng;  Zhong,Ya-Ting;  Gao,Song;  Zhou,Bing;  Liu,Lei;  Kong,Deling;  Hao,Xiaojiang;  Hu,Junjie;  Chen,Quan
浏览  |  Adobe PDF(25423Kb)  |  收藏  |  浏览/下载：40/20  |  提交时间：2024/07/25
ENDOPLASMIC-RETICULUM  PROVIDE INSIGHT  MITOFUSIN 2  MFN1  DYNAMICS  REQUIRES  DEFECTS  FISSION  CELLS  
Design, Synthesis, and Evaluation of the COX-2 Inhibitory Activities of New 1,3-Dihydro-2H-indolin-2-one Derivatives 期刊论文
MOLECULES, 2023, 卷号: 28, 期号: 12, 页码: 4668
作者:  Pan,Taohua;  He,Maofei;  Deng,Lulu;  Li,Jiang;  Fan,Yanhua;  Hao,Xiaojiang;  Mu,Shuzhen
浏览  |  Adobe PDF(3057Kb)  |  收藏  |  浏览/下载：52/11  |  提交时间：2024/05/09
oxindoles  alpha,beta-unsaturated ketone  anti-inflammatory  COX-2 inhibitory activity  ANTIINFLAMMATORY ACTIVITY  NATURAL-PRODUCTS  OXINDOLE-DERIVATIVES  NITRIC-OXIDE  POTENT  CYCLOOXYGENASE-2  DISCOVERY  PAIN  LIABILITY  
New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit beta-Amyloid42 Production and Phospho-Tau (Thr217) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1487
作者:  Li,Sheng;  Han,Ling-Ling;  Huang,Ke-Pu;  Ma,Ye-Han;  Guo,Ling-Li;  Guo,Yarong;  Ran,Xiaoqian;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rongcan;  Zhang,Yu
浏览  |  Adobe PDF(5266Kb)  |  收藏  |  浏览/下载：51/14  |  提交时间：2024/05/09
Tabernaemontana crassa  monoterpenoid indole alkaloids  A beta 42  phospho-tau (Thr217)  Alzheimer's disease  ALZHEIMERS-DISEASE  BISINDOLE ALKALOIDS  CDK5  GEMFIBROZIL  PREVENTION  ALGORITHM  AUTOPHAGY  MODELS  PLANTS  MOUSE  
Quassinoids from Twigs of Harrisonia perforata (Blanco) Merr and Their Anti-Parkinson's Disease Effect 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 22, 页码: 16196
作者:  Cai,Min;  Bai,Xiao-Lin;  Zang,Hao-Jing;  Tang,Xiao-Han;  Yan,Ying;  Wan,Jia-Jia;  Peng,Min-You;  Liang,Hong;  Liu,Lin;  Guo,Feng;  Zhao,Pei-Ji;  Liao,Xun;  Di,Ying-Tong;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(2612Kb)  |  收藏  |  浏览/下载：65/12  |  提交时间：2024/05/09
Harrisonia perforata  quassinoid  simarubaceae  neuroprotection  PC12 cells  PINK1(B9) flies  PROMISING BIOLOGICAL-ACTIVITY  UNPRECEDENTED QUASSINOIDS  
Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 9, 页码: 8113
作者:  Xu,Xinglian;  Deng,Lulu;  Tang,Yaling;  Li,Jiang;  Zhong,Ting;  Hao,Xiaojiang;  Fan,Yanhua;  Mu,Shuzhen
浏览  |  Adobe PDF(5829Kb)  |  收藏  |  浏览/下载：55/16  |  提交时间：2024/05/09
leukemia  sanguinarine  c-MET  MAPK  PI3K/mTOR  STAT3  MET