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The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4461Kb)  |  收藏  |  浏览/下载：253/71  |  提交时间：2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Novel dual-color drug screening model for GLUT4 translocation in adipocytes 期刊论文
MOLECULAR AND CELLULAR PROBES, 2019, 卷号: 43, 页码: 6-12
作者:  Lu, Yanting;  Ma, Xiuli;  Kong, Qinghua;  Xu, Yuhui;  Hu, Jing;  Wang, Fang;  Qin, Wanying;  Wang, Libin;  Xiong, Wenyong
浏览  |  Adobe PDF(1287Kb)  |  收藏  |  浏览/下载：246/59  |  提交时间：2019/03/18
GLUT4  pHluorin  Screening  Glucose uptake  
Modulation of glucose metabolism by a natural compound from Chloranthus japonicus via activation of AMP-activated protein kinase 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 778
作者:  Hu, Rongkuan;  Yan, Huan;  Fei, Xiaoyan;  Liu, Haiyang;  Wu, Jiarui
浏览  |  Adobe PDF(2283Kb)  |  收藏  |  浏览/下载：268/57  |  提交时间：2017/06/01
Super-resolution microscopy reveals the insulin-resistanceregulated reorganization of GLUT4 on plasma membranes 期刊论文
Journal of Cell Science, 2017, 卷号: 130, 页码: 396-405
作者:  Lan Gao;  Junling Chen;  Jing Gao;  Hongda Wang;  Wenyong Xiong
浏览  |  Adobe PDF(9565Kb)  |  收藏  |  浏览/下载：146/33  |  提交时间：2018/06/20
RACK1 is required for adipogenesis 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2016, 卷号: 311, 期号: 5, 页码: C831-C836
作者:  Kong, Qinghua;  Gao, Lan;  Niu, Yanfen;  Gongpan, Pianchou;  Xu, Yuhui;  Li, Yan;  Xiong, Wenyong
浏览  |  Adobe PDF(1017Kb)  |  收藏  |  浏览/下载：331/53  |  提交时间：2017/02/14
Rack1  3t3-l1  Adipogenesis  Wnt  Pi3k-akt-mtor-s6k  
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice 期刊论文
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:  Feng, Li;  Luo, Huan;  Xu, Zhijian;  Yang, Zhuo;  Du, Guoxin;  Zhang, Yu;  Yu, Lijing;  Hu, Kaifeng;  Zhu, Weiliang;  Tong, Qingchun;  Chen, Kaixian;  Guo, Fujiang;  Huang, Cheng;  Li, Yiming
浏览  |  Adobe PDF(841Kb)  |  收藏  |  浏览/下载：258/101  |  提交时间：2016/08/22
Alternative Binding Site  Bavachinin  Canonical Ligand-binding Pocket  Carbohydrate Metabolism  Lipid Metabolism  Pan-ppar Agonist  Synergistic Effects  
Super-resolution microscopy reveals the reorganization of GLUT4 on plasma membrane regulated by insulin resistance 期刊论文
J Cell Sci, 2016, 期号: 1, 页码: 1
作者:  xiong wenyong
浏览  |  Adobe PDF(2616Kb)  |  收藏  |  浏览/下载：243/81  |  提交时间：2017/03/21
Gene Expression and Correlation of Pten and Fabp4 in Liver, Muscle, and Adipose Tissues of Type 2 Diabetes Rats 期刊论文
MEDICAL SCIENCE MONITOR, 2015, 卷号: 21, 期号: 8, 页码: 3616-3621
作者:  Su,Di;  Zhang,Chuan-ling;  Gao,Ying-chun;  Liu,Xiao-ying;  Li,Cai-ping;  Jian Huangfu;  Xiao,Rui
浏览  |  Adobe PDF(265Kb)  |  收藏  |  浏览/下载：170/59  |  提交时间：2016/01/19
Fatty Acid-binding Proteins  Diabetes Mellitus  Pten Phosphohydrolase  Type 2  
A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes. 期刊论文
Natural products and bioprospecting, 2015, 卷号: 5, 期号: 3, 页码: 159-166
作者:  Qin,Ji-Huan;  Ma,Jun-Zeng;  Yang,Xing-Wei;  Hu,Ying-Jie;  Zhou,Juan;  Fu,Lin-Chun;  Tian,Ru-Hua;  Liu,Shan;  Xu,Gang;  Shen,Xiao-Ling
浏览  |  Adobe PDF(2011Kb)  |  收藏  |  浏览/下载：207/32  |  提交时间：2017/02/28
Mangiferin and its aglycone, norathyriol, improve glucose metabolism by activation of AMP-activated protein kinase 期刊论文
PHARMACEUTICAL BIOLOGY, 2014, 卷号: 52, 期号: 1, 页码: 68-73
作者:  Wang, Fang;  Yan, Juming;  Niu, Yanfen;  Li, Yan;  Lin, Hua;  Liu, Xu;  Liu, Jikai;  Li, Ling
浏览  |  Adobe PDF(383Kb)  |  收藏  |  浏览/下载：302/67  |  提交时间：2014/04/09
Active Metabolite  Ampk  Insulin Resistance  L6 Muscle Cells  Norathyriol