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New Phenolic Dimers from Plant Paeonia suffruticosa and Their Cytotoxicity and NO Production Inhibition 期刊论文
Molecules, 2023
作者:  Qianqian Meng;  Shunyao Tong;  Yuqing Zhao;  Xingrong Peng;  Zhenghui Li;  Tao Feng;  Jikai Liu
浏览  |  Adobe PDF(1414Kb)  |  收藏  |  浏览/下载：487/79  |  提交时间：2023/10/07
High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：38/9  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Sesquiterpenoids from the Resina Commiphora Promoting the Apoptotic Activity of PC-3 Prostate Cancer Cells 期刊论文
CHEMISTRY & BIODIVERSITY, 2023
作者:  Dong,Lu;  Li,Yanpeng;  Qin,Fuying;  Cheng,Yongxian
浏览  |  Adobe PDF(1864Kb)  |  收藏  |  浏览/下载：23/8  |  提交时间：2024/07/10
Resina Commiphora  germacrane sesquiterpenes  cell viability  apoptosis  PC-3 cells  ANTIOXIDANT  MYRRHA  BERRYI  MUKUL  
Guaiane-type Sesquiterpenoid Dimers from Artemisia zhongdianensis and Antihepatoma Carcinoma Activity via the p38MAPK Pathway 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2023, 卷号: 41, 期号: 19, 页码: 2453-2468
作者:  Dong,Wei;  Ma,Wen-Jing;  Ma,Yun-Bao;  Li,Feng-Jiao;  Li,Tian-Ze;  Wang,Yong-Cui;  He,Xiao-Feng;  Geng,Chang-An;  Zhang,Xue-Mei;  Chen,Ji-Jun
浏览  |  Adobe PDF(3816Kb)  |  收藏  |  浏览/下载：22/11  |  提交时间：2024/07/10
Artemzhongdianolides B1-B17  Artemisia zhongdianensis  Guaiane-type sesquiterpenoid dimers  Antihepatoma activity  p38MAPK pathway  Cancer  NMR spectroscopy  X-ray diffraction  ARREST  CELLS  JNK  
UPLC-Q-Orbitrap-MS/MS-Guided Isolation of Bioactive Withanolides from the Fruits of Physalis angulata 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 44, 页码: 16581-16592
作者:  Wang,Peng;  Yang,Xiao-Meng;  Hu,Zhan-Xing;  Li,Ya-Nan;  Yang,Jue;  Hao,Xiao-Jiang;  Yuan,Chun-Mao;  Yi,Ping
浏览  |  Adobe PDF(3336Kb)  |  收藏  |  浏览/下载：29/8  |  提交时间：2024/07/10
Physalis angulata  rare withanolidederivatives  isolation and identification  anticancer  anti-inflammatory activity  CYTOTOXIC WITHANOLIDES  CONSTITUENTS  PLANTS  L.  
Discovery of potential novel TRPC5 inhibitors by virtual screening and bioassay 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 94, 页码: 117477
作者:  Shen,Meiling;  Li,Lingfeng;  Li,Yue;  Gu,Xi;  Bai,Longhui;  Xia,Chengfeng;  Xiong,Wenyong;  Zuo,Zhili
浏览  |  Adobe PDF(6089Kb)  |  收藏  |  浏览/下载：31/11  |  提交时间：2024/07/22
TRPC5  Inhibitors  Virtual screening  Ca 2+channel  CHANNELS  IDENTIFICATION  PERMEABILITY  CALCIUM  
Development of actein derivatives as potent anti-triple negative breast cancer agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 89, 页码: 129307
作者:  Zhang,Honglin;  Chen,Yiyan;  Huang,Songwen;  Xiao,Wen-Wen;  Qiu,Ming-Hua;  Shao,Li-Dong;  Chen,Chuan-Huizi;  Li,Dashan
浏览  |  Adobe PDF(1187Kb)  |  收藏  |  浏览/下载：21/6  |  提交时间：2024/07/22
Actein  Modification  Triple negative breast cancer  Structure-activity relationships  Mechanism  GROWTH-INHIBITORY ACTIVITY  BLACK COHOSH  EXTRACTS  
Discovery of diverse sesquiterpenoids from Magnolia grandiflora with cytotoxic activities by inducing cell apoptosis 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 106707
作者:  Xu,Shuangyu;  Tang,Yunyan;  Li,Yanan;  Yang,Jue;  Gu,Wei;  Hao,Xiaojiang;  Yuan,Chunmao
浏览  |  Adobe PDF(5040Kb)  |  收藏  |  浏览/下载：18/9  |  提交时间：2024/07/22
Magnolia grandiflora  Sesquiterpenoids  Isolation and structural modification  Cytotoxic activity  Apoptosis  LACTONES  DERIVATIVES  LEAVES  AGENTS  
Amichalasines F-J: cytochalasan heterotrimers with mirror-imaged core structures from Aspergillus micronesiensis 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 10, 期号: 14, 页码: 3530-3536
作者:  Wu,Zhaodi;  Zhang,Xiaotian;  Li,Qin;  Tong,Qingyi;  Yang,Jing;  Chen,Chunmei;  Zhu,Hucheng;  Zhang,Yonghui
浏览  |  Adobe PDF(1619Kb)  |  收藏  |  浏览/下载：13/5  |  提交时间：2024/07/22
ENDOPHYTIC FUNGUS  RING-SYSTEM  DIMER  
Cytotoxic C-20 non-oxygenated ent-kaurane diterpenoids from Isodon wardii 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106512
作者:  Tan,Qian;  Hu,Kun;  Li,Xiao-Nian;  Yang,Xing-Zhi;  Sun,Han-Dong;  Puno,Pema-Tenzin
浏览  |  Adobe PDF(3171Kb)  |  收藏  |  浏览/下载：22/8  |  提交时间：2024/07/22
Isodon wardii  ent-Kauranoids  Cytotoxicity  Apoptosis  Cell cycle