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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：10/2  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Isolation and identification of hemostatic steroidal glycosides from Ypsilandra thibetica 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 106268
作者:  Ma,Wen-Yi;  Xie,Jing;  Yu,Ling-Ling;  Zhang,Shi-Juan;  Ni,Wei;  Yan,Huan;  Liu,Hai-Yang
浏览  |  Adobe PDF(2307Kb)  |  收藏  |  浏览/下载：17/4  |  提交时间：2024/07/22
Ypsilandra thibetica  Steroidal saponins  Ypsilandrosides Z1-Z14  Hemostatic activity  Structure-activity relationship  SPIROSTANE GLYCOSIDES  NMR-SPECTROSCOPY  AGGREGATION  SAPOGENINS  SAPONINS  
Unraveling the serial glycosylation in the biosynthesis of steroidal saponins in the medicinal plant Paris polyphylla and their antifungal action 期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 11, 页码: 4638-4654
作者:  Chen,Yuegui;  Yan,Qin;  Ji,Yunheng;  Bai,Xue;  Li,Desen;  Mu,Rongfang;  Guo,Kai;  Yang,Minjie;  Tao,Yang;  Gershenzon,Jonathan;  Liu,Yan;  Li,Shenghong
浏览  |  Adobe PDF(2988Kb)  |  收藏  |  浏览/下载：52/13  |  提交时间：2024/05/09
Paris polyphylla var. yunnanensis  Steroidal saponins  Glycosyltransferases  Sugar chain elongation  Antifungal activity  CHEMICAL-CONSTITUENTS  GLYCOSYLTRANSFERASES  GLYCOSIDES  DIVERSITY  CULTIVATION  PATHWAY  FAMILY  PARTS  GENUS  STEP  
Cytotoxic and pro-apoptotic effects of botanical drugs derived from the indigenous cultivated medicinal plant Paris polyphylla var. yunnanensis 期刊论文
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1100825
作者:  Yan,Xiu-Xiang;  Zhao,Yan-Qiang;  He,Yun;  Disayathanoowat,Terd;  Pandith,Hataichanok;  Inta,Angkhana;  Yang,Li-Xin
浏览  |  Adobe PDF(3195Kb)  |  收藏  |  浏览/下载：29/5  |  提交时间：2024/05/09
Paris polyphylla var  yunnanensis  indigenous medicine knowledge  saponins  cytotoxic effects  pro-apoptotic effects  CELL-CYCLE ARREST  STEROIDAL SAPONINS  HEPATOCELLULAR-CARCINOMA  CHEMICAL-CONSTITUENTS  ASSAY  GLYCOSIDES  LEAVES  GROWTH  STEMS  SITES  
The protective effect of Allium chinense on anti-cerebral anoxia through regulating NLRP3/NF-?B 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2023, 卷号: 196, 页码: 116499
作者:  Xiao,Xia;  Liu,Yang-Yang;  Yan,Xiao-Jun;  Wang,Xiao-Na;  Hu,Bin-Yuan;  Chen,Song;  Zhu,Yan-Yan;  Wang,Zhao-Jie;  Xie,Tian-Zhen;  He,Ying-Jie;  Zhao,Li-Xing;  Zhao,Yun-Li;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2824Kb)  |  收藏  |  浏览/下载：4/1  |  提交时间：2024/07/30
Allium chinense  Cerebral anoxia  Intracellular reactive oxygen species  NLRP3  NF-?B  Nutritional strategy  ACID  MITOCHONDRIA  CONTRIBUTES  METALATION  INHIBITORS  SAPONINS  DAMAGE