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Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
浏览  |  Adobe PDF(5724Kb)  |  收藏  |  浏览/下载：391/43  |  提交时间：2017/12/18
Potential role of CYP1B1 in the development and treatment of metabolic diseases 期刊论文
PHARMACOLOGY & THERAPEUTICS, 2017, 卷号: 178, 页码: 18-30
作者:  Li, Fei;  Zhu, Weifeng;  Gonzalez, Frank J.
浏览  |  Adobe PDF(2083Kb)  |  收藏  |  浏览/下载：187/61  |  提交时间：2017/11/20
Cyp1b1  Metabolic Diseases  Metabolic Pathways  Metabolomics  
Polysaccharides of Dendrobium officinale Kimura & Migo protect gastric mucosal cell against oxidative damage-induced apoptosis in vitro and in vivo 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2017, 卷号: 208, 页码: 214-224
作者:  Zeng, Qiang;  Ko, Chun-Hay;  Siu, Wing-Sum;  Li, Long-Fei;  Han, Xiao-Qiang;  Yang, Liu;  Lau, Clara Bik-San;  Hu, Jiang-Miao;  Leung, Ping-Chung
浏览  |  Adobe PDF(1075Kb)  |  收藏  |  浏览/下载：297/73  |  提交时间：2017/10/23
Polysaccharides  Dendrobium Officinale Kimura & Migo  Gastric Injury  Oxidative Damage  Apoptosis  
Anti-HIV Activities and Mechanism of 12-O-Tricosanoylphorbol-20-acetate, a Novel Phorbol Ester from Ostodes katharinae 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 9, 页码: 1498
作者:  Chen, Huan;  Zhang, Rong;  Luo, Rong-Hua;  Yang, Liu-Meng;  Wang, Rui-Rui;  Hao, Xiao-Jiang;  Zheng, Yong-Tang
浏览  |  Adobe PDF(1939Kb)  |  收藏  |  浏览/下载：212/42  |  提交时间：2017/10/23
Antiviral Agent  12-o-tricosanoylphorbol-20-acetate  Hiv  Vif  Apobec3g  Phorbol Ester  
Teuvincenone F Suppresses LPS-Induced Inflammation and NLRP3 Inflammasome Activation by Attenuating NEMO Ubiquitination 期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8, 页码: 565
作者:  Zhao, Xibao;  Pu, Debing;  Zhao, Zizhao;  Zhu, Huihui;  Li, Hongrui;  Shen, Yaping;  Zhang, Xingjie;  Zhang, Ruihan;  Shen, Jianzhong;  Xiao, Weilie;  Chen, Weilin
浏览  |  Adobe PDF(3100Kb)  |  收藏  |  浏览/下载：185/58  |  提交时间：2017/10/23
Teuvincenone f  Inflammation  Nlrp3 Inflammasome  Ubiquitination  Nemo  
Synthesis of selective 11 beta-HSD1 inhibitors based on dammarane scaffold 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 135, 页码: 324-338
作者:  Shao, Li-Dong;  Bao, Ying;  Shen, Yu;  Su, Jia;  Leng, Ying;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1336Kb)  |  收藏  |  浏览/下载：318/74  |  提交时间：2017/07/31
11 Beta-hsd1 Inhibitor  Hupehenols  Dammarane  Sar  
Click Glycosylation for the Synthesis of 1,2,3-Triazole-Linked Picropodophyllotoxin Glycoconjugates and Their Anticancer Activity 期刊论文
CHEMISTRYSELECT, 2017, 卷号: 2, 期号: 18, 页码: 5038-5044
作者:  Zi, Cheng-Ting;  Yang, Liu;  Gao, Wei;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Hu, Jiang-Miao;  Jiang, Zi-Hua
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Anticancer Activity  Cu(i)-catalyzed Click Reaction  Glycoconjugates  Picropodophyllotoxin  Podophyllotoxin  
The opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 977-989
作者:  Yi, Shou-pu;  Kong, Qing-hong;  Li, Yu-lei;  Pan, Chen-ling;  Yu, Jie;  Cui, Ben-qiang;  Wang, Ying-fei;  Wang, Guan-lin;  Zhou, Pei-lan;  Wang, Li-li;  Gong, Ze-hui;  Su, Rui-bin;  Shen, Yue-hai;  Yu, Gang;  Chang, Kwen-jen
浏览  |  Adobe PDF(854Kb)  |  收藏  |  浏览/下载：359/72  |  提交时间：2017/08/29
Opioid Receptor  Mixed Agonist  Dpi-125  Analgesia  Respiratory Depression  Addiction  
Asymmetric total synthesis of (-)-perforanoid A 期刊论文
TETRAHEDRON, 2017, 卷号: 73, 期号: 26, 页码: 3612-3621
作者:  Lv, Chao;  Tu, Qian;  Gong, Jianxian;  Hao, Xiaojiang;  Yang, Zhen
浏览  |  Adobe PDF(1315Kb)  |  收藏  |  浏览/下载：210/71  |  提交时间：2017/07/31
(-)-perforanoid a  Lemonoids  Asymmetric Total Synthesig  Rhodium Catalyzed  Intramolecular Pauson-khand  
Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 11, 页码: 4680-4692
作者:  Qu, Chunrong;  Ding, Mingmin;  Zhu, Yingmin;  Lu, Yungang;  Du, Juan;  Miller, Melissa;  Tian, Jinbin;  Zhu, Jinmei;  Xui, Jian;  Wen, Meng;  Er-Bu, Aga;  Wan, Jule;  Xiao, Yuling;  Wu, Meng;  McManus, Owen B.;  Li, Min;  Wu, Jilin;  Luo, Huai-Rong;  Cao, Zhengyu;  Shen, Bing;  Wang, Hongbo;  Zhu, Michael X.;  Hong, Xuechuan
浏览  |  Adobe PDF(1969Kb)  |  收藏  |  浏览/下载：217/77  |  提交时间：2017/08/29