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Ciclopirox olamine sensitizes leukemia cells to natural killer cell-mediated cytolysis by upregulating NKG2DLs via the Akt signaling pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 卷号: 659, 页码: 10-19
作者:  Zhu,Yiying;  Zhao,Zhangxun;  Xue,Minggao;  Wang,Dan;  Su,Guifeng;  Ju,Xiaoman;  Yang,Qihong;  Zhang,Shaohua;  Fan,Dongmei;  Zhu,Huifang;  Yu,Min;  Li,Yan;  Kong,Lingmei;  Zhou,Hongyu
浏览  |  Adobe PDF(3425Kb)  |  收藏  |  浏览/下载：13/2  |  提交时间：2024/07/22
Ciclopirox olamine  Natural killer cells  NKG2D ligands  Immunotherapy  LIGANDS  RECEPTOR  GROWTH  
Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
作者:  Yang,Qihong;  Qin,Tong;  An,Tao;  Wu,Hongna;  Xu,Gang;  Xiang,Jin;  Lei,Kangfan;  Zhang,Shaohua;  Xia,Jie;  Su,Guifeng;  Wang,Dan;  Xue,Minggao;  Kong,Lingmei;  Zhang,Wenxuan;  Wu,Song;  Li,Yan
浏览  |  Adobe PDF(7197Kb)  |  收藏  |  浏览/下载：4/2  |  提交时间：2024/07/30
PORCN inhibitor  WHN-88  Palmitoylation  Wnt-driven cancers  SIGNALING PATHWAY  PORCUPINE  STEM  GENE  ACYLTRANSFERASE  MUTATIONS  POLARITY  PROTEIN  RNF43  MICE  
Cytochalasans from the Endophytic Fungus Phomopsis sp. shj2 and Their Antimigratory Activities 期刊论文
JOURNAL OF FUNGI, 2022, 卷号: 8, 期号: 5, 页码: 543
作者:  Yan, Bing-Chao;  Wang, Wei-Guang;  Kong, Ling-Mei;  Tang, Jian-Wei;  Du, Xue;  Li, Yan;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(1464Kb)  |  收藏  |  浏览/下载：43/12  |  提交时间：2024/04/30
endophytic fungus  Phomopsis  cytochalasan  antimigratory activity  DERIVATIVES  
Synthesis and biological evaluation of novel 3-benzylcoumarin-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 4, 页码: 6
作者:  Wang, Xue-Quan;  Chen, Xue-Bing;  Ye, Ping-Ting;  Yang, Zhi-Xin;  Bai, Meng-Jiao;  Duan, Su-Yue;  Li, Yan;  Yang, Xiao-Dong
收藏  |  浏览/下载：211/0  |  提交时间：2020/03/18
3-Benzylcoumarin  Imidazolium salts  Biological evaluation  Cytotoxic activity  Structure-activity relationships  
Synthesis and biological activity of new bisbenzofuran-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020
作者:  Wang, Xue-Quan;  Ye, Ping-Ting;  Bai, Meng-Jiao;  Miu, Wei-Hang;  Yang, Zhi-Xin;  Duan, Su-Yue;  Li, Tian-Tian;  Li, Yan;  Yang, Xiao-Dong
浏览  |  Adobe PDF(2161Kb)  |  收藏  |  浏览/下载：171/27  |  提交时间：2021/01/05
Design and synthesis of novel artemisinin hybrids with potent activities against human colorectal cancer cells in vitro and in vivo (vol 182, 111665, 2019) 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020
作者:  Wang, Liang-Liang;  Kong, Lingmei;  Liu, Hui;  Zhang, Yunqin;  Zhang, Li;  Liu, Xingyong;  Yuan, Feng;  Li, Yan;  Zuo, Zhili
浏览  |  Adobe PDF(169Kb)  |  收藏  |  浏览/下载：140/35  |  提交时间：2021/01/05
RNF220 is required for cerebellum development and regulates medulloblastoma progression through epigenetic modulation of Shh signaling 期刊论文
DEVELOPMENT, 2020
作者:  Ma, Pengcheng;  An, Tao;  Zhu, Liang;  Zhang, Longlong;  Wang, Huishan;  Ren, Biyu;  Sun, Bin;  Zhou, Xia;  Li, Yan;  Mao, Bingyu
浏览  |  Adobe PDF(1986Kb)  |  收藏  |  浏览/下载：121/34  |  提交时间：2021/01/05
Design and synthesis of novel artemisinin derivatives with potent activities against colorectal cancer in vitro and in vivo 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 10
作者:  Wang, Liang-Liang;  Kong, Lingmei;  Liu, Hui;  Zhang, Yunqin;  Zhang, Li;  Liu, Xingyong;  Yuan, Feng;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载：139/0  |  提交时间：2020/03/02
Artemisinin  Quinazoline  Hybridization  Colorectal cancer  Chemotherapy  
Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin 期刊论文
CELL CHEMICAL BIOLOGY, 2019, 卷号: 26, 期号: 8, 页码: 1122-+
作者:  Zhu, Huifang;  Wang, Bin;  Kong, Lingmei;  An, Tao;  Li, Gentao;  Zhou, Hongyu;  Gong, Liang;  Zhao, Zhangxun;  Gong, Yaxiao;  Sun, Handong;  Puno, Pematenzin;  Li, Yan
浏览  |  Adobe PDF(4600Kb)  |  收藏  |  浏览/下载：202/38  |  提交时间：2019/10/14
Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168, 页码: 232-252
作者:  Deng, Guogang;  Zhou, Bei;  Wang, Jing;  Chen, Zhuo;  Gong, Liang;  Gong, Yaxiao;  Wu, Dongmei;  Li, Yan;  Zhang, Hongbin;  Yang, Xiaodong
浏览  |  Adobe PDF(1727Kb)  |  收藏  |  浏览/下载：277/42  |  提交时间：2019/07/29
Diosgenin  Cholesterol  Dehydroepiandrosterone  Imidazolium salt  Antitumor activities  Structure-activity relationships