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Synthesis and biological evaluation of novel 3-benzylcoumarin-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 4, 页码: 6
作者:  Wang, Xue-Quan;  Chen, Xue-Bing;  Ye, Ping-Ting;  Yang, Zhi-Xin;  Bai, Meng-Jiao;  Duan, Su-Yue;  Li, Yan;  Yang, Xiao-Dong
收藏  |  浏览/下载:177/0  |  提交时间:2020/03/18
3-Benzylcoumarin  Imidazolium salts  Biological evaluation  Cytotoxic activity  Structure-activity relationships  
Anti-NLRP3 inflammasome abietane diterpenoids from Callicarpa bodinieri and their structure elucidation 期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 2, 页码: 427-430
作者:  Gao, Junbo;  Zhang, Xingjie;  Shang, Kun;  Zhong, Weimao;  Zhang, Ruihan;  Dai, Xiaochang;  Li, Xiaoli;  Wang, Qi;  Zou, Yan;  Xiao, Weilie
收藏  |  浏览/下载:152/0  |  提交时间:2020/03/24
Callicarpa bodinieri  Abietane-type diterpenoids  DP4+NMR calculation  Anti-inflammation  Pyroptosis  NLRP3 inflammasome  
Chemical and biological comparison of different parts of Paeonia suffruticosa (Mudan) based on LCMS-IT-TOF and multi-evaluation in vitro 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2020, 卷号: 144, 页码: 9
作者:  Pan, Yang;  Gao, Zhen;  Huang, Xiao-Yan;  Chen, Ji-Jun;  Geng, Chang-An
收藏  |  浏览/下载:203/0  |  提交时间:2020/03/24
Paeonia suffruticosa  Chemical profiles  LCMS-IT-TOF analyses  Biological comparison  Neurotransmitter receptors  Enzyme inhibition  
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载:166/0  |  提交时间:2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Exploring Aporphine as Anti-inflammatory and Analgesic Lead from Dactylicapnos scandens 期刊论文
ORGANIC LETTERS, 2020, 卷号: 22, 期号: 1, 页码: 257-260
作者:  Wang, Bei;  Zhao, Yin-Jiao;  Zhao, Yun-Li;  Liu, Ya-Ping;  Li, Xiao-Nian;  Zhang, Hongbin;  Luo, Xiao-Dong
收藏  |  浏览/下载:129/0  |  提交时间:2020/03/18
Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts 期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
作者:  Yang, Jun-Li;  Ma, Yong-Hui;  Li, Yan-Hua;  Zhang, Yi-Peng;  Tian, Hong-Chang;  Huang, Yuan-Cheng;  Li, Yan;  Chen, Wen;  Yang, Li-Juan
浏览  |  Adobe PDF(2215Kb)  |  收藏  |  浏览/下载:213/50  |  提交时间:2020/03/18
Identification and Characterization of ShSPI, a Kazal-Type Elastase Inhibitor from the Venom of Scolopendra Hainanum 期刊论文
TOXINS, 2019, 卷号: 11, 期号: 12, 页码: 13
作者:  Luan, Ning;  Zhao, Qiyu;  Duan, Zilei;  Ji, Mengyao;  Xing, Meichen;  Zhu, Tengyu;  Mwangi, James;  Rong, Mingqiang;  Liu, Jiangxin;  Lai, Ren
浏览  |  Adobe PDF(2415Kb)  |  收藏  |  浏览/下载:180/31  |  提交时间:2020/03/18
centipede  kazal-type inhibitor  human neutrophils elastase  ShSPI  
Four new sesquiterpene derivatives from Dendrobium findlayanum 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 900-905
作者:  Yang Dan;  Cheng Zhong-Quan;  Zi Cheng-Ting;  Yang Liu;  Dong Fa-Wu;  Hu Jiang-Miao;  Zhou Jun
浏览  |  Adobe PDF(477Kb)  |  收藏  |  浏览/下载:167/35  |  提交时间:2020/03/18
Dendrobium findlayanum  Sesquiterpene derivatives  Alloaromadendrane  Cyclopacamphane  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载:189/30  |  提交时间:2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Pu-Erh Tea Relaxes the Thoracic Aorta of Rats by Reducing Intracellular Calcium 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 13
作者:  Luo, Dan;  Chen, Xuejiao;  Zhu, Xu;  Liu, Shuang;  Li, Jie;  Xu, Jianping;  Zhao, Jinhua;  Ji, Xu
浏览  |  Adobe PDF(4082Kb)  |  收藏  |  浏览/下载:272/40  |  提交时间:2020/03/18
endothelium-independent vasodilation  hypertension  pu-erh tea  tea components  theabrownins