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Ciclopirox olamine sensitizes leukemia cells to natural killer cell-mediated cytolysis by upregulating NKG2DLs via the Akt signaling pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 卷号: 659, 页码: 10-19
作者:  Zhu,Yiying;  Zhao,Zhangxun;  Xue,Minggao;  Wang,Dan;  Su,Guifeng;  Ju,Xiaoman;  Yang,Qihong;  Zhang,Shaohua;  Fan,Dongmei;  Zhu,Huifang;  Yu,Min;  Li,Yan;  Kong,Lingmei;  Zhou,Hongyu
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Ciclopirox olamine  Natural killer cells  NKG2D ligands  Immunotherapy  LIGANDS  RECEPTOR  GROWTH  
Hybrids of β-triketone and monoterpenoids from the peels of Callistemon viminalis 期刊论文
FITOTERAPIA, 2023, 卷号: 166, 页码: 105459
作者:  Meng,Qing-Hong;  Liu,Hui;  Ling,Shan -Shan;  Yan,Huan;  Liu,Hai-Yang
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Callistemon viminalis  Meroterpenoids  Viminalisones A -D  Antibacterial activity  DIELS-ALDER ADDUCTS  ACYLPHLOROGLUCINOL DERIVATIVES  LEAVES  FRUITS  
Discovery and biological evaluation of a new type of dual inhibitors of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase from ethnomedicinal plant Dactylicapnos scandens 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 214, 页码: 113794
作者:  Bao,Mei-Fen;  Yang,Xin-Ni;  Wu,Jing;  Liu,Jiang-Xin;  Cai,Xiang-Hai
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Dactylicapnos scandens (D. don) hutch.  Isoquinoline alkaloids  Aporphine-type alkaloids  Dactycapnine a  IDO1/TDO dual inhibitor  APORPHINE ALKALOIDS  N-OXIDE  INFLAMMATION  PATHWAY  THALIPORPHINE  COMPLEXES  CANCER  ROOTS  
Steccherins A-D, chamigrane-type sesquiterpenes from the fungus Steccherinum ochraceum with selective inhibition on B lymphocyte proliferation 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 214, 页码: 113830
作者:  Huang,Shan-Shan;  Yang,Hui-Xiang;  He,Juan;  Yan,Bing-Chao;  Feng,Tao;  Liu,Ji-Kai
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Steccherinum ochraceum  Chamigrane sesquiterpenes  Steccherins A-D  Immunosuppressive activity  
Isoxerophilins A and B, two diterpene heterodimers from Isodon xerophilus: structural elucidation and semisynthesis of isoxerophilin analogues 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 11, 期号: 1, 页码: 37-46
作者:  Dai,Jia-Meng;  Yan,Bing-Chao;  Kong,Ling-Mei;  Hu,Kun;  Li,Xing-Ren;  Li,Xiao-Nian;  Sun,Han-Dong;  Li,Yan;  Puno,Pema-Tenzin
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ENT-KAURANE DITERPENOIDS  ABIETANE DITERPENOIDS  A-D  DIMERS  OXIDATION  CYCLOADDUCTS  ACTIVATION  LIGANDS  IBX  
A Modified 1H-NMR Quantification Method of Ephedrine Alkaloids in Ephedrae Herba Samples 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 14, 页码: 11272
作者:  Li,Yue-Chiun;  Wu,Chia-Hung;  Le,Thi Ha;  Yuan,Qingjun;  Huang,Luqi;  Chen,Guo-Fen;  Yang,Mei-Lin;  Lam,Sio-Hong;  Hung,Hsin-Yi;  Sun,Handong;  Wu,Yi-Hung;  Kuo,Ping-Chung;  Wu,Tian-Shung
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ephedrine alkaloid  Ephedrae Herba  cyclized derivative  quantitative nuclear magnetic resonance spectroscopy (qNMR)  two-dimensional NMR (2D NMR)  QUANTITATIVE-ANALYSIS  PSEUDOEPHEDRINE  CHROMATOGRAPHY  URINE  SINICA  (-)-EPHEDRINE  SUPPLEMENTS  EXTRACTION  DRUGS  
Six Unprecedented Cytochalasin Derivatives from the Potato Endophytic Fungus Xylaria curta E10 and Their Cytotoxicity 期刊论文
PHARMACEUTICALS, 2023, 卷号: 16, 期号: 2, 页码: 193
作者:  Zhang,Xian;  Fan,Yinzhong;  Ye,Ke;  Pan,Xiaoyan;  Ma,Xujun;  Ai,Honglian;  Shi,Baobao;  Liu,Jikai
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endophyte fungus  Xylaria curta  cytochalasins  isolation and structure elucidation  cytotoxicity  A-D  METABOLITES  
Two new triterpenoids from the stems of Euphorbia royleana 期刊论文
NATURAL PRODUCT RESEARCH, 2023
作者:  Liu,Wen-Xing;  Zhang,Man;  Zhang,Ying-Jun;  Zhao,Ping
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Euphorbia royleana  triterpenoids  2D NMR  DITERPENES  LATEX  
先导化合物设计与开发 学位论文
: 中国科学院大学, 2022
作者:  Munikishore Rachakunta
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Buxus alkaloids  Buxus alkaloids  Cyclovirobuxine-D  Cyclovirobuxine-D  Synthesis, Calcium channel inhibitors  Synthesis, Calcium channel inhibitors  SAR studies  SAR studies  Anti-cardiovascular agents.  Anti-cardiovascular agents.  
Cyclovirobuxine D, a cardiovascular drug from traditional Chinese medicine, alleviates inflammatory and neuropathic pain mainly via inhibition of voltage-gated Ca(v)3.2 channels 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 1081697
作者:  Su, Deyuan;  Gong, Ye;  Li, Songyu;  Yang, Jian;  Nian, Yin
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Cyclovirobuxine D  Ca(v)3  2  Ca(v)2  Buxus microphylla  analgesic effects  ROOT GANGLION NEURONS  CALCIUM-CHANNELS  CELL-PROLIFERATION  PACLITAXEL  RAT  RECEPTOR  GENE  EXPRESSION  APOPTOSIS  CURRENTS