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Small-Molecule Drugs in Immunotherapy 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 13, 页码: 1341-1359
作者:  Hao,Xuanrun;  Chen,Zhongliang;  Li,Haining;  Wei,Minqin;  Zuo,Zhili;  Su,Qing
浏览  |  Adobe PDF(29350Kb)  |  收藏  |  浏览/下载：34/5  |  提交时间：2024/07/25
Cancer immunotherapy  inhibitors  Pd-1/Pd-L1 inhibitor  IDO inhibitor  STING agonists  ROR gamma t agonists  TGF  beta inhibitors  INDOLEAMINE 2,3-DIOXYGENASE  SIGNALING INHIBITOR  DENDRITIC CELLS  GROWTH  TUMOR  PATHWAY  PEMBROLIZUMAB  RECEPTORS  DISCOVERY  VADIMEZAN  
Comprehensive transcriptomic profiling reveals complex molecular mechanisms in the regulation of style-length dimorphism in Guettarda speciosa (Rubiaceae), a species with anomalous distyly 期刊论文
FRONTIERS IN PLANT SCIENCE, 2023, 卷号: 14, 页码: 1116078
作者:  Luo,Zhonglai;  Zhao,Zhongtao;  Xu,Yuanqing;  Shi,Miaomiao;  Tu,Tieyao;  Pei,Nancai;  Zhang,Dianxiang
浏览  |  Adobe PDF(2134Kb)  |  收藏  |  浏览/下载：92/16  |  提交时间：2024/05/09
anomalous distyly  brassinosteroid signaling  Guettarda speciosa  heterostyly  molecular regulation  genetic convergence  PRIMULA-VULGARIS  GENE-EXPRESSION  ANNOTATION  PATHWAY  IDENTIFICATION  AUXIN  EVOLUTION  PROTEIN  GROWTH  BKI1  
Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
作者:  Yang,Qihong;  Qin,Tong;  An,Tao;  Wu,Hongna;  Xu,Gang;  Xiang,Jin;  Lei,Kangfan;  Zhang,Shaohua;  Xia,Jie;  Su,Guifeng;  Wang,Dan;  Xue,Minggao;  Kong,Lingmei;  Zhang,Wenxuan;  Wu,Song;  Li,Yan
浏览  |  Adobe PDF(7197Kb)  |  收藏  |  浏览/下载：37/10  |  提交时间：2024/07/30
PORCN inhibitor  WHN-88  Palmitoylation  Wnt-driven cancers  SIGNALING PATHWAY  PORCUPINE  STEM  GENE  ACYLTRANSFERASE  MUTATIONS  POLARITY  PROTEIN  RNF43  MICE  
Polysaccharide-Peptide from Trametes versicolor: The Potential Medicine for Colorectal Cancer Treatment 期刊论文
BIOMEDICINES, 2022, 卷号: 10, 期号: 11, 页码: 2841
作者:  He, Zhicheng;  Lin, Jian;  He, Yingying;  Liu, Shubai
浏览  |  Adobe PDF(8865Kb)  |  收藏  |  浏览/下载：113/6  |  提交时间：2024/04/30
Trametes versicolor  polysaccharide peptide  colorectal cancer  traditional medicine  PROTEIN-BOUND POLYSACCHARIDE  QUEL PS-K  CORIOLUS-VERSICOLOR  IN-VITRO  ANTICANCER ACTIVITY  SIGNALING PATHWAY  ANTITUMOR  CELLS  MUSHROOM  COMBINATION  
Polysaccharide Peptide Induced Colorectal Cancer Cells Apoptosis by Down-Regulating EGFR and PD-L1 Expression 期刊论文
IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 2022, 卷号: 21, 期号: 1, 页码: e123909
作者:  Lin Jian;  He Zhicheng;  Liu Shubai
浏览  |  Adobe PDF(3879Kb)  |  收藏  |  浏览/下载：33/2  |  提交时间：2024/08/21
Colorectal Cancer  Trametes Versicolor  EGFR  PD-L1  Polysaccharide Peptide  CORIOLUS-VERSICOLOR  SIGNALING PATHWAY  COLON-CANCER  T-CELLS  STATISTICS  THERAPY  
Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 3, 页码: 588-601
作者:  Li,Xu-xia;  Zhang,Peng;  Yang,Yang;  Wang,Jing-jing;  Zheng,Yan-jun;  Tan,Ji-liang;  Liu,Shen-yan;  Yan,Yong-ming;  Zhang,You-yi;  Cheng,Yong-xian;  Yang,Huang-tian
浏览  |  Adobe PDF(4052Kb)  |  收藏  |  浏览/下载：122/5  |  提交时间：2022/04/02
cardiac hypertrophy  pyrazine derivative  QF84139  phenylephrine  transverse aortic constriction  AMPK signaling pathway  PROTEIN-KINASE  MAMMALIAN TARGET  OVERLOAD  METFORMIN  MACROPHAGES  MECHANISMS  MEDICINE  ALPHA  CELLS  MODEL  
Paris Saponin VII Induces Apoptosis and Cell Cycle Arrest in Erythroleukemia Cells by a Mitochondrial Membrane Signaling Pathway 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 4, 页码: 498-507
作者:  Lin,Xin;  Gajendran,Babu;  Varier,Krishnapriya M.;  Liu,Wuling;  Song,Jingrui;  Rao,Qing;  Wang,Chunlin;  Qiu,Jianfei;  Ni,Wei;  Qin,XuJie;  Wen,Min;  Liu,Haiyang;  Li,Yanmei
收藏  |  浏览/下载：142/0  |  提交时间：2022/04/02
Leukemia  Paris Saponin VII  HEL  cell cycle  apoptosis  membrane signaling pathway  
Artematrolide A inhibited cervical cancer cell proliferation via ROS/ERK/mTOR pathway and metabolic shift 期刊论文
PHYTOMEDICINE, 2021, 卷号: 91, 页码: 153707
作者:  Zhang,Xin-Tian;  Hu,Jing;  Su,Li-Hua;  Geng,Chang-An;  Chen,Ji-Jun
浏览  |  Adobe PDF(6313Kb)  |  收藏  |  浏览/下载：232/49  |  提交时间：2022/04/02
Artemisia atrovirens  Cervical cancer  ERK pathway  Cell metabolism  ALKALINE-PHOSPHATASE  SIGNALING PATHWAY  DIFFERENTIATION  APOPTOSIS  ERK  MECHANISMS  
Platelet-activating factor acetyl hydrolase IB2 dysregulated cell proliferation in ovarian cancer 期刊论文
CANCER CELL INTERNATIONAL, 2021, 卷号: 21, 期号: 1, 页码: 697
作者:  He,YingYing;  He,Zhicheng;  Zhang,Xiaoyu;  Liu,Shubai
浏览  |  Adobe PDF(2666Kb)  |  收藏  |  浏览/下载：109/23  |  提交时间：2022/04/02
Ovarian cancer  Ester lipid  Tyrosine kinase signaling pathway  Platelet-activating factor  FACTOR-ACETYLHYDROLASE ACTIVITY  LYSOPHOSPHATIDIC ACID  FACTOR RECEPTOR  EMERGING ROLE  EXPRESSION  GROWTH  PAF  MECHANISMS  PAFAH1B3  SUBUNIT  
An update on the function and regulation of methylerythritol phosphate and mevalonate pathways and their evolutionary dynamics 期刊论文
JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 2021, 卷号: 63, 期号: 7, 页码: 1211-1226
作者:  Pu,Xiaojun;  Dong,Xiumei;  Li,Qing;  Chen,Zexi;  Liu,Li
收藏  |  浏览/下载：177/0  |  提交时间：2022/04/02
evolutionary innovation  MEP pathway  MVA pathway  retrograde signaling  stress