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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Pharmacological characterizationof tachykinin tetrabranched derivatives
期刊论文
出版物, 3111, 期号: 0, 页码: 1-36
作者:
Chiara Ruzza
;
Anna Rizzi
;
Davide Malfacini
;
Maria Camilla Cerlesi
;
Federica Ferrari
;
Erika Marzola
;
Caterina Ambrosio
;
Cristina Gro
;
Salvadori Severo
;
Tommaso Costa
;
Girolamo Calo
;
Remo Guerrini
Adobe PDF(1277Kb)
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浏览/下载:136/1
  |  
提交时间:2017/07/24
Tachykinins
Substance p
Pwt2-sp
Nk1 Receptor
Calcium Mobilization
Bioluminescence Resonance Energy Transfer
Guinea Pig Ileum
Rat Urinary Bladder
Nociceptive Behaviour Induced By Spinal Substance p
Mice
Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii
期刊论文
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:
Dai,Manyun
;
Peng,Wan
;
Lin,Lisha
;
Wu,Zhanxuan
;
Zhang,Ting
;
Zhao,Qi
;
Cheng,Yan
;
Lin,Qiuxia
;
Zhang,Binbin
;
Liu,Aiming
;
Rao,Qianru
;
Huang,Jianfeng
;
Zhao,Jinhua
;
Gonzalez,Frank J.
;
Li,Fei
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Adobe PDF(17974Kb)
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浏览/下载:7/2
  |  
提交时间:2024/07/17
Intestinal bleeding
Triptolide
Celastrol
Intestinal FXR
Tripterygium wilfordii
FARNESOID-X-RECEPTOR
BACTERIAL TRANSLOCATION
ACTIVATION
INFLAMMATION
DYSFUNCTION
TRIPTOLIDE
MICROBIOTA
PREVENTS
OBESITY
MICE
Metabolomics Reveals Gut Microbiota Contribute to PPARα Deficiency-Induced Alcoholic Liver Injury
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2023, 卷号: 22, 期号: 7, 页码: 2327-2338
作者:
Zhang,Ting
;
Bao,Lijuan
;
Zhao,Qi
;
Wu,Zhanxuan E. E.
;
Dai,Manyun
;
Rao,Qianru
;
Li,Fei
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Adobe PDF(9616Kb)
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浏览/下载:5/1
  |  
提交时间:2024/07/10
metabolomics
alcohol-induced liver injury
gut microbiota
PPAR & alpha
AROMATIC-AMINO-ACIDS
LIPID-METABOLISM
FED MICE
MODULATION
DISEASE
AXIS
OLEOYLETHANOLAMIDE
AGONIST
OBESITY
DEATH
Metabolomics Reveals Gut Microbiota Contribute to PPAR & alpha; Deficiency-Induced Alcoholic Liver Injury
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2023
作者:
Zhang,Ting
;
Bao,Lijuan
;
Zhao,Qi
;
Wu,Zhanxuan E. E.
;
Dai,Manyun
;
Rao,Qianru
;
Li,Fei
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Adobe PDF(9616Kb)
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浏览/下载:7/1
  |  
提交时间:2024/07/10
metabolomics
alcohol-induced liver injury
gut microbiota
PPAR & alpha
AROMATIC-AMINO-ACIDS
LIPID-METABOLISM
FED MICE
MODULATION
DISEASE
AXIS
OLEOYLETHANOLAMIDE
AGONIST
OBESITY
DEATH
Quinoline derivatives and macamides from Maca (Lepidium meyenii)
期刊论文
PHYTOCHEMISTRY LETTERS, 2023, 卷号: 57, 页码: 62-66
作者:
Zang,Zhen
;
Wang,Li
;
Lei,Ze
;
Yang,Fumei
;
Li,Xiaonian
;
Sun,Qianyun
;
Zhao,Yong
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Adobe PDF(563Kb)
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浏览/下载:5/3
  |  
提交时间:2024/07/22
Lepidium meyenii
Quinolines
Macamides
Inhibitory activity
CONSTITUENTS
MICE
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:
Zhou,Gui-Feng
;
Tang,Jing
;
Ma,Yuan-Lin
;
Fu,Xian
;
Liu,Jun-Yan
;
Yang,Ren-Zhi
;
Zhang,Hong-Sheng
;
Cai,Xiang-Hai
;
Wang,Jing-Wen
;
Xie,Xiao-Yong
;
Song,Li
;
Luo,Biao
;
Chen,Jian
;
Chen,Long
;
Deng,Xiao-Juan
;
Chen,Guo-Jun
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Adobe PDF(6685Kb)
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浏览/下载:59/13
  |  
提交时间:2024/05/09
conophylline
ARL6IP1
5'UTR
FXR1
BACE1 translation
AMYLOID PRECURSOR PROTEIN
A-BETA
TRANSGENIC MICE
MOUSE MODEL
NEURODEGENERATION
EXPRESSION
REDUCTION
MEMBRANE
MEMORY
ER
Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
作者:
Yang,Qihong
;
Qin,Tong
;
An,Tao
;
Wu,Hongna
;
Xu,Gang
;
Xiang,Jin
;
Lei,Kangfan
;
Zhang,Shaohua
;
Xia,Jie
;
Su,Guifeng
;
Wang,Dan
;
Xue,Minggao
;
Kong,Lingmei
;
Zhang,Wenxuan
;
Wu,Song
;
Li,Yan
Adobe PDF(7197Kb)
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浏览/下载:8/3
  |  
提交时间:2024/07/30
PORCN inhibitor
WHN-88
Palmitoylation
Wnt-driven cancers
SIGNALING PATHWAY
PORCUPINE
STEM
GENE
ACYLTRANSFERASE
MUTATIONS
POLARITY
PROTEIN
RNF43
MICE
Methanolic extract of Cariniana rubra Gardner ex Miers stem bark negatively regulate the leukocyte migration and TNF-alpha and up-regulate the annexin-A1 expression
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113778
作者:
Paulino Brandao Silva,Donata Norman
;
Adriana,Flach
;
de Oliveira Martins,Domingos Tabajara
;
Borges,Quessi Irias
;
Nunes Lindote,Marcus Vitor
;
Ramalho Zoratti,Marco Tulio
;
de Oliveira,Ruberlei Godinho
;
Vieira Torquato,Heron Fernandes
;
Gazoni,Vanessa Fatima
;
Alves da Costa,Luiz Antonio Mendonca
;
Alexandre de Souza,Edineide Cristina
;
Araujo da Silva,Felipe Moura
;
Arunachalam,Karuppusamy
;
Damazo,Amilcar Sabino
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浏览/下载:52/0
  |  
提交时间:2022/04/02
Cariniana rubra, anti-inflammatory
Air pouch
TNF-alpha
Annexin A1
Gallic acid
Terpenes
Mice
GENE-EXPRESSION
INFLAMMATION
FPR2-based anti-inflammatory and anti-lipogenesis activities of novel meroterpenoid dimers from Ganoderma
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105338
作者:
Peng,Xing-Rong
;
Wang,Qian
;
Wang,Hui-Rong
;
Hu,Kun
;
Xiong,Wen-Yong
;
Qiu,Ming-Hua
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Adobe PDF(7004Kb)
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浏览/下载:104/15
  |  
提交时间:2022/04/02
Ganoderma applanatum
Meroterpenoid dimers
Molecular docking
Anti-lipogenesis
FPR2-based inflammation
INDUCED INSULIN-RESISTANCE
ADIPOCYTE DIFFERENTIATION
OBESITY
INFLAMMATION
DEFICIENCY
MACROPHAGES
ACTIVATION
EXPRESSION
LIGAND
MICE
PPAR alpha activation protects against cholestatic liver injury
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 9967
作者:
Zhao, Qi
;
Yang, Rui
;
Wang, Jing
;
Hu, Dan-Dan
;
Li, Fei
浏览
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Adobe PDF(7693Kb)
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收藏
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浏览/下载:257/63
  |  
提交时间:2017/10/23
Primary Biliary-cirrhosis
Bile-acid Homeostasis
Receptor-alpha
Ursodeoxycholic Acid
Cholesterol 7-alpha-hydroxylase
Beta-oxidation
Fenofibrate
Therapy
Mice
Hepatotoxicity