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The extracts of Lobaria pindarensis, an edible lichen from Himalayas, suppress inflammatory response and fibrillation of amyloid β-protein in cultured microglial cells: Active depsidones, norstictic acid and stictic acid, are responsible for the functions 期刊论文
JOURNAL OF FUNCTIONAL FOODS, 2023, 卷号: 107, 页码: 105607
作者:  Yang,Mei-Xia;  Cheng,Edwin Hok-Chi;  Ospondpant,Dusadee;  Tung,Ka-Ki;  Wang,Li-Song;  Lin,Sheng-Ying;  Lai,Queenie Wing-Sze;  Wu,Qi-Yun;  Xia,Ying-Jie;  Leung,Ka-Wing;  Duan,Ran;  Dong,Tina Ting-Xia;  Tsim,Karl Wah-Keung
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Alzheimer's disease  Inflammation  Fibrillar A beta  Lichen  Lobaria pindarensis  Depsidone  IN-SILICO  IDENTIFICATION  INHIBITORS  
Artemeriosides A-F, the first examples of natural sesquiterpenoids substituted by a 6′-O-crontonyl β-glucopyranoside from Artemisia annua 期刊论文
FITOTERAPIA, 2023, 卷号: 169, 页码: 105619
作者:  He,Xiao-Feng;  Wang,Meng-Fei;  Ma,Yun-Bao;  Li,Tian-Ze;  Chen,Ji-Jun
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Artemisia annua L.  Artemeriosides A-F  Sesquiterpenoids substituted by 6'-O-crontonyl  beta-glucopyranoside  Antihepatoma activity  GENUS  
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:  Zhou,Gui-Feng;  Tang,Jing;  Ma,Yuan-Lin;  Fu,Xian;  Liu,Jun-Yan;  Yang,Ren-Zhi;  Zhang,Hong-Sheng;  Cai,Xiang-Hai;  Wang,Jing-Wen;  Xie,Xiao-Yong;  Song,Li;  Luo,Biao;  Chen,Jian;  Chen,Long;  Deng,Xiao-Juan;  Chen,Guo-Jun
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conophylline  ARL6IP1  5'UTR  FXR1  BACE1 translation  AMYLOID PRECURSOR PROTEIN  A-BETA  TRANSGENIC MICE  MOUSE MODEL  NEURODEGENERATION  EXPRESSION  REDUCTION  MEMBRANE  MEMORY  ER  
New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit beta-Amyloid42 Production and Phospho-Tau (Thr217) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1487
作者:  Li,Sheng;  Han,Ling-Ling;  Huang,Ke-Pu;  Ma,Ye-Han;  Guo,Ling-Li;  Guo,Yarong;  Ran,Xiaoqian;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rongcan;  Zhang,Yu
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Tabernaemontana crassa  monoterpenoid indole alkaloids  A beta 42  phospho-tau (Thr217)  Alzheimer's disease  ALZHEIMERS-DISEASE  BISINDOLE ALKALOIDS  CDK5  GEMFIBROZIL  PREVENTION  ALGORITHM  AUTOPHAGY  MODELS  PLANTS  MOUSE  
Nor-lupane triterpenoid and guaiane sesquiterpenoids from Schefflera venulosa 期刊论文
FITOTERAPIA, 2015, 卷号: 103, 页码: 294-298
作者:  Peng, Li-Yan;  Xu, Gang;  He, Juan;  Wu, Xing-De;  Dong, Liao-Bin;  Gao, Xiu;  Cheng, Xiao;  Su, Jia;  Li, Yan;  Dong, Wen-Ming;  Zhao, Qin-Shi
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Schefflera Venulosa  Nor-lupane Triterpenoid  Sesquiterpenoids  3-oxo-29 Alpha-hydroxy-17 Beta  Schvenols A-b  20-epoxy-28-norlupane  
Isolation and Complete Structural Assignment of Lycopodium Alkaloid Cernupalhine A: Theoretical Prediction and Total Synthesis Validation 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 10, 页码: 2700-2703
作者:  Dong, Liao-Bin;  Wu, Ya-Nan;  Jiang, Shi-Zhi;  Wu, Xing-De;  He, Juan;  Yang, Yu-Rong;  Zhao, Qin-Shi
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Fawcettimine-related Alkaloids  Alpha  Unified Total Syntheses  Beta-unsaturated Carbonyl-compounds  Palhinhaea-cernua  Unprecedented Skeleton  Helquist Annulation  A-c  Japonicum  (-)-8-deoxyserratinine  (+)-lycoflexine  
New Lycopodium alkaloids from Phlegmariurus squarrosus 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2014, 卷号: 16, 期号: 6, 页码: 574-580
作者:  Liu, Fei;  Dong, Liao-Bin;  Gao, Xiu;  Wu, Xing-De;  He, Juan;  Peng, Li-Yan;  Cheng, Xiao;  Zhao, Qin-Shi;  Zhao, QS (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China.;  qinshizhao@mail.kib.ac.cn
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Phlegmariurus Squarrosus  Lycopodium Alkaloids  8 Alpha-hydroxylycojapodine a  8 Beta-acetoxy-12 Beta-hydroxy-epidihydrolycopodine  8 Beta-acetyllycoposerramine-u  11 Beta-acetoxyl-n-methylhuperzine b  
Three novel beta-carboline alkaloids from Gelsemium elegans 期刊论文
FITOTERAPIA, 2012, 卷号: 83, 期号: 4, 页码: 704-708
作者:  Zhang, Zhen;  Zhang, Yu;  Wang, Yue-Hu;  Zhang, Qiang;  Yan, Xiao-Hui;  Di, Ying-Tong;  He, Hong-Ping;  Hao, Xiao-Jiang
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Loganiaceae  Gelsemium Elegans  Beta-carboline Alkaloids  Gelebolines A-c  Biogenetic Relationship  
beta-Carboline alkaloids from the leaves of Trigonostemon lii YT Chang 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 6, 页码: 2296-2299
作者:  Li, Shi-Fei;  Zhang, Yu;  Li, Yan;  Li, Xin-Rao;  Kong, Ling-Mei;  Tan, Cheng-Jian;  Li, Shun-Lin;  Di, Ying-Tong;  He, Hong-Ping;  Hao, Xiao-Jiang
Adobe PDF(228Kb)  |  收藏  |  浏览/下载：566/196  |  提交时间：2012/06/07
Trigonostemon Lii  Beta-carboline Alkaloids  Trigonostemines A-f  Cytotoxic Activity  
Dual Carbamoylations on the Polyketide and Glycosyl Moiety by Asm21 Result in Extended Ansamitocin Biosynthesis 期刊论文
CHEMISTRY & BIOLOGY, 2011, 卷号: 18, 期号: 12, 页码: 1571-1580
作者:  Li, Yan;  Zhao, Peiji;  Kang, Qianjin;  Ma, Juan;  Bai, Linquan;  Deng, Zixin
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Antitumor Agent Ansamitocin  Beta-lactam Antibiotics  Actinosynnema-pretiosum  Gene-cluster  Dna Gyrase  Concanamycin-a  Streptomyces  Novobiocin  Carbamoyltransferase  Inhibitors