Artemeriosides A-F, the first examples of natural sesquiterpenoids substituted by a 6′-O-crontonyl β-glucopyranoside from Artemisia annua

doi:10.1016/j.fitote.2023.105619

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	Artemeriosides A-F, the first examples of natural sesquiterpenoids substituted by a 6′-O-crontonyl β-glucopyranoside from Artemisia annua
	He,Xiao-Feng; Wang,Meng-Fei; Ma,Yun-Bao; Li,Tian-Ze; Chen,Ji-Jun
	2023
发表期刊	FITOTERAPIA
ISSN	1873-6971
卷号	169 页码:105619
摘要	Artemeriosides A-F (1-6), six novel sesquiterpenoids containing a 6'-O-crontonyl beta-glucopyranoside, were isolated from Artemisia annua L. Their structures were determined by spectral data including HRESIMS, IR, UV, 1D and 2D NMR, and ECD calculations. Compounds 1-6 represented the first examples of natural sesquiterpenoid substituted by 6 '-O-crontonyl beta-glucopyranoside. By antihepatoma assay, compounds 1 and 2 demonstrated inhibitory effect against both HepG2 and SK-Hep-1 cells with inhibitory ratios of 77.0%, 88.8%, and 86.8%, 83.9% at 200.0 mu M, and compound 1 showed inhibitory activity against Huh7 cells with inhibitory ratio of 56.8%.
关键词	Artemisia annua L. Artemeriosides A-F Sesquiterpenoids substituted by 6'-O-crontonyl beta-glucopyranoside Antihepatoma activity GENUS
DOI	10.1016/j.fitote.2023.105619
收录类别	SCI
WOS记录号	WOS:001050461500001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75508
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	He,Xiao-Feng,Wang,Meng-Fei,Ma,Yun-Bao,等. Artemeriosides A-F, the first examples of natural sesquiterpenoids substituted by a 6′-O-crontonyl β-glucopyranoside from Artemisia annua[J]. FITOTERAPIA,2023,169:105619.
APA	He,Xiao-Feng,Wang,Meng-Fei,Ma,Yun-Bao,Li,Tian-Ze,&Chen,Ji-Jun.(2023).Artemeriosides A-F, the first examples of natural sesquiterpenoids substituted by a 6′-O-crontonyl β-glucopyranoside from Artemisia annua.FITOTERAPIA,169,105619.
MLA	He,Xiao-Feng,et al."Artemeriosides A-F, the first examples of natural sesquiterpenoids substituted by a 6′-O-crontonyl β-glucopyranoside from Artemisia annua".FITOTERAPIA 169(2023):105619.

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