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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：73/11  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Phytochemical Analysis and Anti-Ascaris suum Activity of Different Zanthoxylum Species In Vitro and In Vivo 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 13, 页码: 5219-5229
作者:  Wang,Zhao-Jie;  Chen,Yi-Chi;  Zou,Feng-Cai;  Qin,Yan;  Zhu,Yan-Yan;  Xiao,Xia;  Xie,Tian-Zhen;  He,Ying-Jie;  Zhao,Yun-li;  Luo,Xiao-Dong
浏览  |  Adobe PDF(8638Kb)  |  收藏  |  浏览/下载：76/23  |  提交时间：2024/07/10
Zanthoxylum plants  anti-roundworm  high-resolution mass spectrometry  collision energy  metabolites  
Targeted quantitative analysis of monoterpenoid indole alkaloids in Alstonia scholaris by ultra-high-performance liquid chromatography coupled with quadrupole time of flight mass spectrometry 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2023
作者:  Qin,Yan;  He,Ying-Jie;  Zhao,Yun-Li;  Zhou,Zhong-Shun;  Wang,Zhao-Jie;  Zhu,Yan-Yan;  Luo,Xiao-Dong
浏览  |  Adobe PDF(3792Kb)  |  收藏  |  浏览/下载：48/11  |  提交时间：2024/07/22
CATHARANTHUS-ROSEUS  ETHANOLIC EXTRACTS  IDENTIFICATION  QUANTIFICATION  HPTLC  
Steroidal alkaloid with unprecedented triheterocyclic architecture 期刊论文
CHEMICAL COMMUNICATIONS, 2023, 卷号: 59, 期号: 3, 页码: 326-329
作者:  Zhou,Zhong-Shun;  Zhao,Yun-Li;  Hu,Bin-Yuan;  Wang,Bei;  Liu,Ya-Ping;  Zhu,Yan-Yan;  He,Ying-Jie;  Wang,Zhao-Jie;  Dai,Zhi;  Zhao,Li-Xing;  Luo,Xiao-Dong
浏览  |  Adobe PDF(975Kb)  |  收藏  |  浏览/下载：65/12  |  提交时间：2024/07/22
MALIC-ACID  SKELETON  
Significant anti-inflammatory aziridine-containing indole alkaloids from the Chinese medicinal plant Alstonia scholaris 期刊论文
CHEMICAL COMMUNICATIONS, 2023, 卷号: 59, 期号: 16, 页码: 2271-2274
作者:  Hu,Bin-Yuan;  Zhao,Yun-Li;  Zhou,Zhong-Shun;  Zhu,Yan-Yan;  Luo,Xiao-Dong
浏览  |  Adobe PDF(1363Kb)  |  收藏  |  浏览/下载：51/9  |  提交时间：2024/07/22
LEAVES  PORFIROMYCIN  
Dimeric benzylisoquinoline alkaloids from Thalictrum delavayi and their biological activities 期刊论文
FITOTERAPIA, 2023, 卷号: 164, 页码: 105356
作者:  Jin,Qiong;  Qin,Xu-Jie;  Dai,Zhi;  Zhao,Yun;  Zhu,Yan-Yan;  Chen,Shan-Shan;  Liu,Ya-Ping;  Luo,Xiao-Dong
浏览  |  Adobe PDF(1861Kb)  |  收藏  |  浏览/下载：38/11  |  提交时间：2024/07/25
Thalictrum delavayi  Ranunculaceae  Bisbenzylisoquinoline alkaloids  Cytotoxicities  Immunosuppressive effects  CYCLOARTANE GLYCOSIDES  APORPHINE  LEAVES  PLANTS  
Steroidal alkaloids from the roots of Veratrum stenophyllum 期刊论文
FITOTERAPIA, 2023, 卷号: 166, 页码: 105464
作者:  Zhou,Zhong-Shun;  Liu,Yang -Yang;  Zhu,Yan-Yan;  Hu,Bin-Yuan;  He,Ying-Jie;  Luo,XiaoDong
浏览  |  Adobe PDF(1511Kb)  |  收藏  |  浏览/下载：38/11  |  提交时间：2024/07/25
Steroidal alkaloids  Veratrum stenophyllum  Cytotoxic bioactivity  ANTITUMOR-ACTIVITY  RHIZOMES  DNA  
The protective effect of Allium chinense on anti-cerebral anoxia through regulating NLRP3/NF-?B 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2023, 卷号: 196, 页码: 116499
作者:  Xiao,Xia;  Liu,Yang-Yang;  Yan,Xiao-Jun;  Wang,Xiao-Na;  Hu,Bin-Yuan;  Chen,Song;  Zhu,Yan-Yan;  Wang,Zhao-Jie;  Xie,Tian-Zhen;  He,Ying-Jie;  Zhao,Li-Xing;  Zhao,Yun-Li;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2824Kb)  |  收藏  |  浏览/下载：27/8  |  提交时间：2024/07/30
Allium chinense  Cerebral anoxia  Intracellular reactive oxygen species  NLRP3  NF-?B  Nutritional strategy  ACID  MITOCHONDRIA  CONTRIBUTES  METALATION  INHIBITORS  SAPONINS  DAMAGE  
Comparison of chemical constituents in diverse zanthoxylum herbs, and evaluation of their relative antibacterial and nematicidal activity 期刊论文
FOOD BIOSCIENCE, 2021, 卷号: 42, 页码: 101206
作者:  Wang,Zhao-Jie;  Zhou,Ying;  Shi,Xiao-Long;  Xia,Xiao;  He,Ying-Jie;  Zhu,Yan-Yan;  Xie,Tian-Zhen;  Liu,Tie;  Xu,Xiang-Juan;  Luo,Xiao-Dong
收藏  |  浏览/下载：87/0  |  提交时间：2022/04/02
Zanthoxylum herbs  Antibacterial  Nematicidal  Mass spectrometry  BUNGEANUM MAXIM.  LIGNANS  IDENTIFICATION  ARMATUM  LEAVES  AMIDES  ROOTS  OILS  
The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial 期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
作者:  Gou,Zhong-Ping;  Zhao,Yun-Li;  Zou,Lin-Ling;  Wang,Ying;  Shu,Shi-Qing;  Zhu,Xiao-Hong;  Zheng,Li;  Shen,Qi;  Luo,Zhu;  Miao,Jia;  Wang,Yong-Sheng;  Luo,Xiao-Dong;  Feng,Ping
收藏  |  浏览/下载：112/0  |  提交时间：2022/04/02
Clinical safety  healthy subject  dose-escalation study  MONOTERPENOID INDOLE ALKALOIDS  FLIGHT MASS-SPECTROMETRY  EXTRACT  IDENTIFICATION  CONSTITUENTS