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Guaiane-type Sesquiterpenoid Dimers from Artemisia zhongdianensis and Antihepatoma Carcinoma Activity via the p38MAPK Pathway 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2023, 卷号: 41, 期号: 19, 页码: 2453-2468
作者:  Dong,Wei;  Ma,Wen-Jing;  Ma,Yun-Bao;  Li,Feng-Jiao;  Li,Tian-Ze;  Wang,Yong-Cui;  He,Xiao-Feng;  Geng,Chang-An;  Zhang,Xue-Mei;  Chen,Ji-Jun
浏览  |  Adobe PDF(3816Kb)  |  收藏  |  浏览/下载：44/15  |  提交时间：2024/07/10
Artemzhongdianolides B1-B17  Artemisia zhongdianensis  Guaiane-type sesquiterpenoid dimers  Antihepatoma activity  p38MAPK pathway  Cancer  NMR spectroscopy  X-ray diffraction  ARREST  CELLS  JNK  
Dirigent gene editing of gossypol enantiomers for toxicity-depleted cotton seeds 期刊论文
NATURE PLANTS, 2023, 卷号: 9, 期号: 4, 页码: 605-+
作者:  Lin,Jia-Ling;  Fang,Xin;  Li,Jian-Xu;  Chen,Zhi-Wen;  Wu,Wen-Kai;  Guo,Xiao-Xiang;  Liu,Ning-Jing;  Huang,Jia-Fa;  Chen,Fang-Yan;  Wang,Ling-Jian;  Xu,Baofu;  Martin,Cathie;  Chen,Xiao-Ya;  Huang,Jin-Quan
浏览  |  Adobe PDF(9213Kb)  |  收藏  |  浏览/下载：55/20  |  提交时间：2024/07/22
DOMAIN-CONTAINING PROTEIN  BIOSYNTHESIS  (-)-GOSSYPOL  SYNTHASE  (+)-GOSSYPOL  METABOLISM  EXPRESSION  REDUCTION  
Design, synthesis, and biological evaluation of artemyrianolide H derivatives as potential antihepatoma agents 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 137, 页码: 106617
作者:  Li,Tian-Ze;  Yang,Xiao-Tong;  Ma,Wen-Jing;  Ma,Yun-Bao;  Li,Feng-Jiao;  Wang,Yong-Cui;  Chen,Ji-Jun
浏览  |  Adobe PDF(9670Kb)  |  收藏  |  浏览/下载：54/12  |  提交时间：2024/07/22
Artemyrianolide H  Germacranolide derivatives  Antihepatoma activity  Apoptosis  DIMERS  
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:  Zhou,Gui-Feng;  Tang,Jing;  Ma,Yuan-Lin;  Fu,Xian;  Liu,Jun-Yan;  Yang,Ren-Zhi;  Zhang,Hong-Sheng;  Cai,Xiang-Hai;  Wang,Jing-Wen;  Xie,Xiao-Yong;  Song,Li;  Luo,Biao;  Chen,Jian;  Chen,Long;  Deng,Xiao-Juan;  Chen,Guo-Jun
浏览  |  Adobe PDF(6685Kb)  |  收藏  |  浏览/下载：110/18  |  提交时间：2024/05/09
conophylline  ARL6IP1  5'UTR  FXR1  BACE1 translation  AMYLOID PRECURSOR PROTEIN  A-BETA  TRANSGENIC MICE  MOUSE MODEL  NEURODEGENERATION  EXPRESSION  REDUCTION  MEMBRANE  MEMORY  ER  
Diverse structures and antihepatoma effect of sesquiterpenoid dimers from Artemisia eriopoda by AKT/STAT signaling pathway 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 64
作者:  He,Xiaofeng;  Ma,Wenjing;  Hu,Jing;  Li,Tianze;  Geng,Changan;  Ma,Yunbao;  Wang,Mengfei;  Yang,Kexin;  Zhang,Xuemei;  Chen,Ji-Jun
浏览  |  Adobe PDF(1548Kb)  |  收藏  |  浏览/下载：69/12  |  提交时间：2024/05/09
Discovery and biosynthesis of karnamicins as angiotensin converting enzyme inhibitors 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 209
作者:  Yu,Zhiyin;  Huang,Jian-Ping;  Yang,Jing;  Liu,Chongxi;  Yan,Yijun;  Wang,Li;  Zhao,Junwei;  Chen,Yin;  Xiang,Wensheng;  Huang,Sheng-Xiong
浏览  |  Adobe PDF(1819Kb)  |  收藏  |  浏览/下载：79/14  |  提交时间：2024/05/09
HYPERTENSION  PREDICTION  FLAVIN  MECHANISM  PATHWAY  OXIDASE  COMPLEX  DOMAIN  SOIL  
Functional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genus Salvia 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 4696
作者:  Hu,Jiadong;  Qiu,Shi;  Wang,Feiyan;  Li,Qing;  Xiang,Chun-Lei;  Di,Peng;  Wu,Ziding;  Jiang,Rui;  Li,Jinxing;  Zeng,Zhen;  Wang,Jing;  Wang,Xingxing;  Zhang,Yuchen;  Fang,Shiyuan;  Qiao,Yuqi;  Ding,Jie;  Jiang,Yun;  Xu,Zhichao;  Chen,Junfeng;  Chen,Wansheng
浏览  |  Adobe PDF(1515Kb)  |  收藏  |  浏览/下载：99/17  |  提交时间：2024/05/09
CARNOSIC ACID  PHYLOGENETIC ANALYSIS  ARABIDOPSIS-THALIANA  GENOME DUPLICATIONS  STAMINAL EVOLUTION  LAMIACEAE  BIOSYNTHESIS  TANSHINONES  TOOL  
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
作者:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
收藏  |  浏览/下载：180/0  |  提交时间：2022/04/02
Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
Catalytic innovation underlies independent recruitment of polyketide synthases in cocaine and hyoscyamine biosynthesis 期刊论文
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 4994
作者:  Tian, Tian;  Wang, Yong-Jiang;  Huang, Jian-Ping;  Li, Jie;  Xu, Bingyan;  Chen, Yin;  Wang, Li;  Yang, Jing;  Yan, Yijun;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(1664Kb)  |  收藏  |  浏览/下载：86/22  |  提交时间：2024/04/30
TROPANE ALKALOID BIOSYNTHESIS  CHAIN-LENGTH CONTROL  
Sinosenecio yangii (Asteraceae), a new species from Guizhou, China 期刊论文
PHYTOKEYS, 2022, 期号: 210, 页码: 1-13
作者:  Peng, Jing-Yi;  Zhang, Dai-Gui;  Deng, Tao;  Huang, Xian-Han;  Chen, Jun-Tong;  Meng, Ying;  Wang, Yi;  Zhou, Qiang
浏览  |  Adobe PDF(5253Kb)  |  收藏  |  浏览/下载：109/18  |  提交时间：2024/03/11