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Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
作者:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
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Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction 期刊论文
NATURE CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 4, 页码: 468-+
作者:  Guo,Yingjie;  Zhang,Huan;  Yan,Chen;  Shen,Birong;  Zhang,Yue;  Guo,Xiangyang;  Sun,Sha;  Yu,Fan;  Yan,Jiayun;  Liu,Ronghe;  Zhang,Qianping;  Zhang,Di;  Liu,Haiyang;  Liu,Yang;  Zhang,Yaoyao;  Li,Wenlei;  Qin,Jiangyu;  Lv,He;  Wang,Zhaoxia;  Yuan,Yun;  Yang,Jie-Feng;  Zhong,Ya-Ting;  Gao,Song;  Zhou,Bing;  Liu,Lei;  Kong,Deling;  Hao,Xiaojiang;  Hu,Junjie;  Chen,Quan
浏览  |  Adobe PDF(25423Kb)  |  收藏  |  浏览/下载：209/42  |  提交时间：2024/07/25
ENDOPLASMIC-RETICULUM  PROVIDE INSIGHT  MITOFUSIN 2  MFN1  DYNAMICS  REQUIRES  DEFECTS  FISSION  CELLS  
Munronin V with 7/7/6 tricarbocyclic framework from Munronia henryi harms inhibits tau pathology by activating autophagy 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 3, 页码: 514-519
作者:  Yan,Ying;  Ran,Xiaoqian;  Wang,Dan;  Zhang,Xiong;  Peng,Mingyou;  Yan,Xiaoyan;  Tang,Lei;  Liang,Hong;  Qin,Xujie;  Di,Ying-Tong;  Luo,Rongcan;  Hao,Xiao-Jiang;  Yao,Yong-Gang
浏览  |  Adobe PDF(1471Kb)  |  收藏  |  浏览/下载：254/88  |  提交时间：2024/07/25
UBIQUITIN-PROTEASOME SYSTEM  ALZHEIMERS-DISEASE  CONSTITUENTS  LIMONOIDS  TFEB  NEURODEGENERATION  
Acetylcholinesterase inhibitory activity of sesquiterpenoids isolated from Laggera pterodonta 期刊论文
FRONTIERS IN PLANT SCIENCE, 2023, 卷号: 14, 页码: 1074184
作者:  Li,Jinliang;  Li,Fengchao;  Wu,Guoxing;  Gui,Furong;  Li,Hongmei;  Xu,Lili;  Hao,Xiaojiang;  Zhao,Yuhan;  Ding,Xiao;  Qin,Xiaoping
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Laggera pterodonta  sesquiterpenes  acetylcholinesterase  enzyme kinetics  toxic effects  DERIVATIVES  FLAVONOIDS  TERPENOIDS  MECHANISM  
Iridoid glycosides from Morinda officinalis induce lysosomal biogenesis and promote autophagic flux to attenuate oxidative stress 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2023
作者:  Wang,Yin-Yuan;  Ni,Jian-Cheng;  Zhao,Yue-Qin;  Yang,Xu;  Niu,Zhen-Peng;  Yang,Xing-Zhi;  Dong,Xian-Xiang;  Zhao,Yu-Han;  Hao,Xiao-Jiang;  Ding,Xiao
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Iridoid glycosides  Morinda officinalis  lysosomal biogenesis  TFEB/TFE3  antioxidant activity  TRANSCRIPTIONAL CONTROL  TFEB  PHOSPHORYLATION  REVEALS  PATHWAY  
Antifeedant Mechanism of Dodonaea viscosa Saponin A Isolated from the Seeds of Dodonaea viscosa 期刊论文
MOLECULES, 2022, 卷号: 27, 期号: 14, 页码: 4464
作者:  Yu, Hang;  Li, Jinliang;  Wu, Guoxing;  Tang, Qingbo;  Duan, Xiuan;  Liu, Quanjun;  Lan, Mingxian;  Zhao, Yuhan;  Hao, Xiaojiang;  Qin, Xiaoping;  Ding, Xiao
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antifeedant  Dodonaea viscosa  Spodoptera litura  taste sensillum  GABA  detoxification enzyme  LITURA LEPIDOPTERA-NOCTUIDAE  SENSORY RESPONSES  FIELD  
Paris Saponin VII Induces Apoptosis and Cell Cycle Arrest in Erythroleukemia Cells by a Mitochondrial Membrane Signaling Pathway 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 4, 页码: 498-507
作者:  Lin,Xin;  Gajendran,Babu;  Varier,Krishnapriya M.;  Liu,Wuling;  Song,Jingrui;  Rao,Qing;  Wang,Chunlin;  Qiu,Jianfei;  Ni,Wei;  Qin,XuJie;  Wen,Min;  Liu,Haiyang;  Li,Yanmei
收藏  |  浏览/下载：239/0  |  提交时间：2022/04/02
Leukemia  Paris Saponin VII  HEL  cell cycle  apoptosis  membrane signaling pathway  
Acylphloroglucinols with acetylcholinesterase inhibitory effects from the fruits of Eucalyptus robusta (vol 103, 104127, 2020) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104579
作者:  Liu,Hui;  He,Xiao-Zhi;  Feng,Mi-Yan;  Zeng,Yuan;  Rauwolf,Tyler J.;  Shao,Li-Dong;  Ni,Wei;  Yan,Hui;  Porco,John A.,Jr.;  Hao,Xiao-Jiang;  Qin,Xu-Jie;  Liu,Hai-Yang
收藏  |  浏览/下载：194/0  |  提交时间：2022/04/02
A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
作者:  Hu,Mi;  Varier,Krishnapriya M.;  Li,Zhicao;  Qin,Xujie;  Rao,Qing;  Song,Jingrui;  Hu,Anling;  Hang,Yubing;  Yuan,Chunmao;  Gajendran,Babu;  Shu,Liping;  Wen,Min;  Li,Yanmei;  Liu,Haiyang
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Acylphloroglucinol  HEL cells  Intrinsic apoptotic pathway  Anti-angiogenesis  STAT3  Flk-1  CALLISTEMON-CITRINUS  TUMOR ANGIOGENESIS  DNA  DERIVATIVES  ANTICANCER  APOPTOSIS  ACTIVATION  INHIBITORS  TARGETS  LEAVES  
Polymethylated acylphloroglucinols from Rhodomyrtus tomentosa exert acetylcholinesterase inhibitory effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104519
作者:  Qin,Xu-Jie;  Liu,Hui;  Li,Pan-Pan;  Ni,Wei;  He,Li;  Khan,Afsar;  Hao,Xiao-Jiang;  Liu,Hai-Yang
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Rhodomyrtus tomentosa  Polymethylated acyphloroglucinols  AChE inhibitory effect  Molecular docking  PHLOROGLUCINOL MEROTERPENOIDS  LEAVES  DERIVATIVES  TWIGS  BETA