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Discovery and bioinspired total syntheses of unprecedented sesquiterpenoid dimers unveiled bifurcating [4+2] cycloaddition and target differentiation of enantiomers 期刊论文
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 4
作者:  He, Tao-Bin;  Yan, Bing-Chao;  Zhou, Yuan-Fei;  Sang, Yue-Qian;  Li, Xiao-Nian;  Sun, Han-Dong;  Wang, Chu;  Xue, Xiao-Song;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(3322Kb)  |  收藏  |  浏览/下载：782/418  |  提交时间：2024/05/09
DIELS-ALDER REACTION  BIOMIMETIC SYNTHESES  EFFICIENT ACCESS  DEHYDROGENATION  CYCLOHEXANONES  BIOSYNTHESIS  CONVERSION  OXIDATION  DYNAMICS  PHENOLS  
Structurally diverse ent-clerodanoids from the aerial parts of Isodon scoparius 期刊论文
PHYTOCHEMISTRY, 2024, 卷号: 228, 页码: 114229
作者:  Jiang, Xue-Chun;  Hu, Kun;  Bai, Xue;  Li, Xing-Ren;  Yan, Bing-Chao;  Chen, Su-Ping;  Li, Xiao-Nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(2061Kb)  |  收藏  |  浏览/下载：0/0  |  提交时间：2025/10/20
Isoxerophilusins A and B, Two Novel Polycyclic Asymmetric Diterpene Dimers from Isodon xerophilus: Structural Elucidation, Modification, and Inhibitory Activities against α-Glucosidase 期刊论文
ORGANIC LETTERS, 2024, 卷号: 26, 期号: 29, 页码: 6203-6208
作者:  Dai, Jia-Meng;  Yan, Bing-Chao;  Hu, Kun;  Li, Xing-Ren;  Li, Xiao-nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
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Silvaticusins A-D: ent-kaurane diterpenoids and a cyclobutane-containing ent-kaurane dimer from Isodon silvaticus. 期刊论文
Natural products and bioprospecting, 2024, 卷号: 14, 期号: 1, 页码: 45-45
作者:  Hai, Qi-Xiu;  Hu, Kun;  Chen, Su-Ping;  Fu, Yang-Yang;  Li, Xiao-Nian;  Sun, Han-Dong;  He, Hong-Ping;  Puno, Pema-Tenzin
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Recent advances in the application of [2+2] cycloaddition in the chemical synthesis of cyclobutane-containing natural products. 期刊论文
Natural products and bioprospecting, 2024, 卷号: 14, 期号: 1, 页码: 37-37
作者:  Hou, Song-Yu;  Yan, Bing-Chao;  Sun, Han-Dong;  Puno, Pema-Tenzin
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Cyclobutane-Containing Meroditerpenoids, (+)-Isoscopariusins B and C: Structure Elucidation and Biomimetic Synthesis 期刊论文
ORGANIC LETTERS, 2023, 卷号: 25, 期号: 17, 页码: 2981-2985
作者:  Li,Ming-Xiang;  Yan,Bing-Chao;  Zhou,Min;  Li,Xing-Ren;  Li,Xiao-nian;  He,Shi-Jun;  Sun,Han-Dong;  Puno,Pema-Tenzin
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2+2 PHOTOCYCLOADDITION REACTIONS  VISIBLE-LIGHT PHOTOCATALYSIS  LEWIS-ACID CATALYSIS  CYCLOADDITIONS  DERIVATIVES  
Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023
作者:  Su,Xiao-Zheng;  Zhang,Lin-Fei;  Hu,Kun;  An,Yang;  Zhang,Qiao-Peng;  Tang,Jian-Wei;  Yan,Bing-Chao;  Li,Xing-Ren;  Cai,Jie;  Li,Xiao-Nian;  Sun,Han-Dong;  Jiang,Shi-You;  Puno,Pema-Tenzin
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Enzymes  Meroterpenoids  Natural Products  Proteomics  Semisynthesis  STATIN  FUNGUS  RISK  ACID  
Phomopsischalins A-C, polycyclic-fused cytochalasins from the endophytic fungus Phomopsis sp. shj2 and their abilities to induce lysosomal function 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 10, 期号: 9, 页码: 2218-2225
作者:  Chen,Rong;  Guo,Li-Jing;  Li,Xue-Dan;  Li,Xing-Ren;  Hu,Kun;  Tang,Jian-Wei;  Ye,Zhen-Nan;  Yan,Bing-Chao;  Puno,Pema-Tenzin
浏览  |  Adobe PDF(1676Kb)  |  收藏  |  浏览/下载：188/48  |  提交时间：2024/07/22
Cytotoxic C-20 non-oxygenated ent-kaurane diterpenoids from Isodon wardii 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106512
作者:  Tan,Qian;  Hu,Kun;  Li,Xiao-Nian;  Yang,Xing-Zhi;  Sun,Han-Dong;  Puno,Pema-Tenzin
浏览  |  Adobe PDF(3171Kb)  |  收藏  |  浏览/下载：554/321  |  提交时间：2024/07/22
Isodon wardii  ent-Kauranoids  Cytotoxicity  Apoptosis  Cell cycle  
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 210, 页码: 115491
作者:  Gou,Leilei;  Yue,Grace Gar-Lee;  Lee,Julia Kin -Ming;  Puno,Pema Tenzin;  Lau,Clara Bik-San
浏览  |  Adobe PDF(16654Kb)  |  收藏  |  浏览/下载：218/29  |  提交时间：2024/07/22
Breast cancer  Metastasis  Natural products  Eriocalyxin B  Cancer recurrence  Cancer stem cells  Gut microbiome  NF-KAPPA-B  STEM-CELLS  MOLECULAR-MECHANISMS  EXTRACELLULAR-MATRIX  TUMOR-GROWTH  APOPTOSIS  ANGIOGENESIS  PROGRESSION  CARCINOMA  LEUKEMIA