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Catalyzed Synthesis of 3-hydroxy-indol-2-one Derivatives as a Novel Phosphodiesterases 10 Inhibitor 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 卷号: 126, 页码: 33-34
作者:  Wu, Ya;  Li, Hao;  Yan, Jiao;  Cai, Qing;  Huang, Shengxiong;  Tang, Ying;  Ji, Yue;  Hao, Xiaojiang;  Chen, Gang
收藏  |  浏览/下载：221/0  |  提交时间：2020/03/24
Synthesis and PDE-10 Inhibition of 3-substituted Phenylimino-indolin-2-ones 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 卷号: 126, 页码: 34-34
作者:  Wu, Ya;  Lin, Zhiwei;  Bai, Yun;  Zhang, Yu;  Cai, Qing;  Mu, Shuzhen;  Han, Weiwei;  Hao, Xiaojiang;  Chen, Gang
收藏  |  浏览/下载：185/0  |  提交时间：2020/03/24
Nukiangendines A and B, two novel 13,14-seco-abietanes from Abies nukiangensis 期刊论文
TETRAHEDRON LETTERS, 2019, 卷号: 60, 期号: 10, 页码: 751-753
作者:  Li, Yong-Li;  Zhang, Qiang;  Wu, Jian-Jun;  Xue, Li-Jun;  Chen, Li-Ming;  Tian, Jun-Mian;  Xu, Zhuo-Ni;  Chen, Ying;  Yang, Xian-Wen;  Hao, Xiao-Jiang;  Li, Jie
浏览  |  Adobe PDF(561Kb)  |  收藏  |  浏览/下载：263/36  |  提交时间：2019/04/15
Abies nukiangensis  seco-Abietane  Diterpene  Antiviral  
The plant sesquiterpene lactone parthenolide inhibits Wnt/-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 14, 页码: 5335-5344
作者:  Zhu, Xiaoliang;  Yuan, Chunmao;  Tian, Chenyang;  Li, Chen;  Nie, Fen;  Song, Xiaomin;  Zeng, Rong;  Wu, Dianqing;  Hao, Xiaojiang;  Li, Lin
收藏  |  浏览/下载：418/0  |  提交时间：2018/05/08
Inhibitor  Protein Synthesis  Small Molecule  T-cell Factor (Tcf)  Wnt Signaling  
Autocatalytic synthesis of 3-ethyl-3-hydroxy-indole-2-ones and their neuroprotection and antitumor activities' evaluation 期刊论文
COMPTES RENDUS CHIMIE, 2018, 卷号: 21, 期号: 5, 页码: 471-474
作者:  Chen, Gang;  Lin, Jiao;  Zhang, Jie;  Wu, Ya;  Gu, Xuefan;  Hao, Xiaojiang;  Zhang, Yu
收藏  |  浏览/下载：137/0  |  提交时间：2019/03/29
Isatin  3-Ethyl-3-hydroxy-indole-2-one  Antitumor  Neuroprotection  
Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/beta-catenin transcriptional activity 期刊论文
CELL DISCOVERY, 2017, 卷号: 3, 页码: 17003
作者:  He, Xiaoli;  Zhang, Wenjuan;  Yan, Chen;  Nie, Fen;  Li, Chen;  Liu, Xiaofen;  Fei, Cong;  Li, Shengdi;  Song, Xiaomin;  Jia, Yingying;  Zeng, Rong;  Wu, Dianqing;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
Adobe PDF(3775Kb)  |  收藏  |  浏览/下载：154/38  |  提交时间：2017/12/18
Carf  Chemical Biology  Nc043  Small Molecule  Wnt Signaling  
Design, Synthesis, and Structural Optimization of Lycorine-Derived Phenanthridine Derivatives as Wnt/beta-Catenin Signaling Pathway Agonists 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 1, 页码: 180-188
作者:  Chen, Duo-Zhi;  Jing, Chen-Xu;  Cai, Jie-Yun;  Wu, Ji-Bo;  Wang, Sheng;  Yin, Jun -Lin;  Li, Xiao-Nian;  Li, Lin;  Hao, Xiao-Jiang
Adobe PDF(3043Kb)  |  收藏  |  浏览/下载：321/76  |  提交时间：2016/06/27
A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30 期刊论文
CELL RESEARCH, 2014, 卷号: 24, 期号: 4, 页码: 482-496
作者:  Yue, Wen;  Chen, Ziheng;  Liu, Haiyang;  Yan, Chen;  Chen, Ming;  Feng, Du;  Yan, Chaojun;  Wu, Hao;  Du, Lei;  Wang, Yueying;  Liu, Jinhua;  Huang, Xiaohu;  Xia, Laixin;  Liu, Lei;  Wang, Xiaohui;  Jin, Haijing;  Wang, Jun;  Song, Zhiyin;  Hao, Xiaojiang;  Chen, Quan
Adobe PDF(1659Kb)  |  收藏  |  浏览/下载：621/58  |  提交时间：2014/05/16
Mitochondrial Fusion  Mitofusin1/2  Deubiquitinase Usp30  15-oxospiramilactone  
Michael Addition between Isatin and Acrylate Derivatives 期刊论文
LETTERS IN ORGANIC CHEMISTRY, 2011, 卷号: 8, 期号: 9, 页码: 614-617
作者:  Chen, Gang;  Tang, Ying;  Zhang, Jie;  Wu, Ya;  Hao, Xiao-Jiang;  Mu, Shu-Zhen
Adobe PDF(164Kb)  |  收藏  |  浏览/下载：540/317  |  提交时间：2012/07/25
Acrylate  Isatin  Beta-(2  Michael Addition  3-dioxoindolin-1-yl) Propanoate  
One chloro-furoeremophilanoid and two new natural dimers from Ligularia atroviolacea 期刊论文
CHINESE CHEMICAL LETTERS, 2008, 卷号: 19, 期号: 11, 页码: 1319-1322
作者:  Zhao, Jun;  Wu, Hao;  Huang, Ke Xin;  Shi, Shu Yun;  Peng, Hua;  Sun, Xian Feng;  Chen, Liu Rong;  Zheng, Qun Xiong;  Zhang, Qi Jun;  Hao, Xiao Jiang;  Stoeckigt, Joachim;  Li, Xiao Kun;  Zhao, Yu;  Qu, Jia
Adobe PDF(195Kb)  |  收藏  |  浏览/下载：421/77  |  提交时间：2011/12/06
Natural Sesquiterpene  Eremophiladiolide  Dimer  Chloro-furanoeremophilane  X-ray  Ligularia Atroviolacea