| Michael Addition between Isatin and Acrylate Derivatives | |
Chen, Gang1; Tang, Ying1; Zhang, Jie1; Wu, Ya1; Hao, Xiao-Jiang2 ; Mu, Shu-Zhen3,4
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| 通讯作者 | Chen, G (reprint author), Xian Shiyou Univ, Coll Chem & Chem Engn, Xian 710065, Peoples R China |
| 2011-11-01 | |
| 发表期刊 | LETTERS IN ORGANIC CHEMISTRY
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| ISSN | 1570-1786 |
| 卷号 | 8期号:9页码:614-617 |
| 摘要 | A simple and efficient Michael addition of isatin to acrylate in the presence of KOH was described. Methyl beta-(2,3-dioxoindolin-1-yl) propanoate was synthesized firstly by the addition of isatin to methyl acrylate in a feasible approach using 10% KOH as catalyst in DMF with the highest yield of 72.5% under the optimized conditions. A series of beta-(2,3-dioxoindolin-1-yl) propanoate derivatives was synthesized according to this approach and gave moderate to relative high yields. The directive distinct color changes in this reaction were illuminated by the reaction mechanism analysis. |
| 关键词 | Acrylate Isatin Beta-(2 Michael Addition 3-dioxoindolin-1-yl) Propanoate |
| 学科领域 | Chemistry |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000299570700002 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/14485 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Xian Shiyou Univ, Coll Chem & Chem Engn, Xian 710065, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 3.Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550002, Peoples R China 4.Chinese Acad Sci, Guiyang 550002, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Gang,Tang, Ying,Zhang, Jie,et al. Michael Addition between Isatin and Acrylate Derivatives[J]. LETTERS IN ORGANIC CHEMISTRY,2011,8(9):614-617. |
| APA | Chen, Gang,Tang, Ying,Zhang, Jie,Wu, Ya,Hao, Xiao-Jiang,&Mu, Shu-Zhen.(2011).Michael Addition between Isatin and Acrylate Derivatives.LETTERS IN ORGANIC CHEMISTRY,8(9),614-617. |
| MLA | Chen, Gang,et al."Michael Addition between Isatin and Acrylate Derivatives".LETTERS IN ORGANIC CHEMISTRY 8.9(2011):614-617. |
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