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题名: Michael Addition between Isatin and Acrylate Derivatives
作者: Chen, Gang1; Tang, Ying1; Zhang, Jie1; Wu, Ya1; null(郝小江)2; Mu, Shu-Zhen3, 4
刊名: LETTERS IN ORGANIC CHEMISTRY
关键词: Acrylate ; beta-(2,3-dioxoindolin-1-yl) propanoate ; isatin ; Michael addition
英文摘要: A simple and efficient Michael addition of isatin to acrylate in the presence of KOH was described. Methyl beta-(2,3-dioxoindolin-1-yl) propanoate was synthesized firstly by the addition of isatin to methyl acrylate in a feasible approach using 10% KOH as catalyst in DMF with the highest yield of 72.5% under the optimized conditions. A series of beta-(2,3-dioxoindolin-1-yl) propanoate derivatives was synthesized according to this approach and gave moderate to relative high yields. The directive distinct color changes in this reaction were illuminated by the reaction mechanism analysis.
出版日期: 2011-11-01
卷号: 8, 期号:9, 页码:614-617
语种: 英语
收录类别: SCI
学科分类: Chemistry
ISSN号: 1570-1786
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/14485
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Xian Shiyou Univ, Coll Chem & Chem Engn, Xian 710065, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
3.Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550002, Peoples R China
4.Chinese Acad Sci, Guiyang 550002, Peoples R China

Recommended Citation:
Chen, G; Tang, Y; Zhang, J; Wu, Y; Hao, XJ; Mu, SZ.Michael Addition between Isatin and Acrylate Derivatives,LETTERS IN ORGANIC CHEMISTRY,2011,8(9):614-617
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