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Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3299-3306
作者:  Chen, Si-Yue;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Yang, Xiao-Tong;  Su, Li-Hua;  He, Xiao-Feng;  Li, Tian-Ze;  Deng, Zhen-Tao;  Gao, Zhen;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1837Kb)  |  收藏  |  浏览/下载：207/37  |  提交时间：2019/09/10
Gastrodia elata  Polybenzyls  Melatonin receptors  Structure-activity relationships  Docking study  
Termipaniculatones A-F, chalcone-flavonone heterodimers from Terminthia paniculata, and their protective effects on hyperuricemia and acute gouty arthritis 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 228-235
作者:  Yang, Tong-Hua;  Yan, De-Xiu;  Huang, Xiao-Yan;  Hou, Bo;  Ma, Yun-Bao;  Peng, Hua;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Geng, Chang-An
浏览  |  Adobe PDF(2111Kb)  |  收藏  |  浏览/下载：276/32  |  提交时间：2019/09/10
Terminthia paniculata (Wall. ex G. Don) CY Wu & TL Ming  Anacardiaceae  Termipaniculatones A-F  Chalcone-flavonone heterodimers  Xanthine oxidase inhibitors  Anti-gout potency  
Antidepressant potential of Uncaria rhynchophylla and its active flavanol, catechin, targeting melatonin receptors 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 232, 页码: 39-46
作者:  Geng, Chang-An;  Yang, Tong-Hua;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(3731Kb)  |  收藏  |  浏览/下载：216/49  |  提交时间：2019/06/24
Uncaria rhynchophylla  Catechin  Melatonin receptors  Metabolites  Antidepressant activity  
Bioactivity-guided synthesis of tropine derivatives as new agonists for melatonin receptors 期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 51, 页码: 45059-45063
作者:  Yin, Xiu-Juan;  Geng, Chang-An;  Huang, Xiao-Yan;  Chen, Hao;  Ma, Yun-Bao;  Chen, Xing-Long;  Sun, Chang-Li;  Yang, Tong-Hua;  Zhou, Jun;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1380Kb)  |  收藏  |  浏览/下载：283/72  |  提交时间：2016/08/22
Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 10, 页码: 2353-2359
作者:  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhao, Yong;  Wang, Li-Jun;  Guo, Rui-Hua;  Liang, Wen-Juan;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(3861Kb)  |  收藏  |  浏览/下载：317/75  |  提交时间：2014/06/23
Anti-hbv Activity  DehydroAndrographolide And  Andrographolide Derivatives  Structure-activity Relationships  Octanol-water Partition Coefficients  
Synthesis of hemslecin A derivatives: A new class of hepatitis B virus inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 5, 页码: 1201-1205
作者:  Guo, Rui-Hua;  Geng, Chang-An;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Quan;  Wang, Li-Jun;  Zhang, Xue-Mei;  Zhang, Rong-Ping;  Chen, Ji-Jun
浏览  |  Adobe PDF(460Kb)  |  收藏  |  浏览/下载：402/94  |  提交时间：2013/03/18
Hemslecin a  Derivatives  Hepatitis b Virus  
Synthesis, structure-activity relationships and biological evaluation of caudatin derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2012, 卷号: 20, 期号: 9, 页码: 2877-2888
作者:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Luo, Jie;  Chen, Hao;  Guo, Rui-Hua;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(2590Kb)  |  收藏  |  浏览/下载：357/125  |  提交时间：2012/06/07
Synthesis  Caudatin Derivatives  Anti-hbv Activity  Structure-activity Relationships  
Anti-Hepatitis B Virus Active Lactones from the Traditional Chinese Herb: Swertia mileensis 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2011, 卷号: 17, 期号: 14, 页码: 3893-3903
作者:  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Luo, Jie;  Guo, Rui-Hua;  Zhou, Jun;  Shen, Yong;  Zuo, Ai-Xue;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(1108Kb)  |  收藏  |  浏览/下载：415/130  |  提交时间：2012/04/10
Antiviral Agents  Biosynthesis  Fused-ring Systems  Hepatitis b Virus  Natural Products  Swerilactones H-k  Swertia Mileensis  
Synthesis and biological assay of 4-aryl-6-chloro-quinoline derivatives as novel non-nucleoside anti-HBV agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 卷号: 19, 期号: 4, 页码: 1400-1408
作者:  Guo, Rui-Hua;  Zhang, Quan;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Luo, Jie;  Wang, Li-Jun;  Geng, Chang-An;  Zhang, Xue-Mei;  Zhou, Jun;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(951Kb)  |  收藏  |  浏览/下载：471/149  |  提交时间：2012/04/10
Hepatitis b Virus  4-aryl-6-chloro-quinoline  Derivatives  Synthesis  
Structure-activity relationships study of 6-chloro-4-(2-chlorophenyl)-3-(2-hydroxyethyl) quinolin-2(1H)-one derivatives as novel non-nucleoside anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 1, 页码: 307-319
作者:  Guo, Rui-Hua;  Zhang, Quan;  Ma, Yun-Bao;  Luo, Jie;  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Zhou, Jun;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(866Kb)  |  收藏  |  浏览/下载：370/95  |  提交时间：2012/04/10
Anti-hepatitis b Virus Activity  Quinolin-2(1h)-one  Structure-activity Relationships