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Polysaccharides of Dendrobium officinale Kimura & Migo protect gastric mucosal cell against oxidative damage-induced apoptosis in vitro and in vivo 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2017, 卷号: 208, 页码: 214-224
作者:  Zeng, Qiang;  Ko, Chun-Hay;  Siu, Wing-Sum;  Li, Long-Fei;  Han, Xiao-Qiang;  Yang, Liu;  Lau, Clara Bik-San;  Hu, Jiang-Miao;  Leung, Ping-Chung
浏览  |  Adobe PDF(1075Kb)  |  收藏  |  浏览/下载：291/71  |  提交时间：2017/10/23
Polysaccharides  Dendrobium Officinale Kimura & Migo  Gastric Injury  Oxidative Damage  Apoptosis  
Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 期号: 0, 页码: 42176
作者:  Li, Mingyue;  Song, Li-Hua;  Yue, Grace Gar-Lee;  Lee, Julia Kin-Ming;  Zhao, Li-Mei;  Li, Lin;  Zhou, Xunian;  Tsui, Stephen Kwok-Wing;  Ng, Simon Siu-Man;  Fung, Kwok-Pui;  Tan, Ning-Hua;  Lau, Clara Bik-San
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Xerophilusin B Induces Cell Cycle Arrest and Apoptosis in Esophageal Squamous Cell Carcinoma Cells and Does Not Cause Toxicity in Nude Mice 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2015, 卷号: 78, 期号: 1, 页码: 10-16
作者:  Yao, Ran;  Chen, Zhaoli;  Zhou, Chengcheng;  Luo, Mei;  Shi, Xuejiao;  Li, Jiagen;  Gao, Yibo;  Zhou, Fang;  Pu, Jianxin;  Sun, Handong;  He, Jie
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Cordycepol C Induces Caspase-Independent Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells 期刊论文
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2014, 卷号: 37, 期号: 4, 页码: 608-617
作者:  Sun, Yi-sheng;  Lv, Long-xian;  Zhao, Zhao;  He, Xian;  You, Lu;  Liu, Ji-kai;  Li, Yong-quan
Adobe PDF(3093Kb)  |  收藏  |  浏览/下载：238/57  |  提交时间：2014/05/16
Cordycepol c  Apoptosis  Bax Protein  Apoptosis-inducing Factor  Endonuclease g  
Ethoxysanguinarine Induces Inhibitory Effects and Downregulates CIP2A in Lung Cancer Cells 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 5, 期号: 2, 页码: 113-118
作者:  Liu, Zi;  Ma, Liang;  Wen, Zhe-Sheng;  Cheng, Yong-Xian;  Zhou, Guang-Biao
Adobe PDF(415Kb)  |  收藏  |  浏览/下载：357/71  |  提交时间：2014/04/09
Ethoxysanguinarine  Cip2a  Lung Cancer  Cell Proliferation  Apoptosis  
Anti-tumour activity of longikaurin A (LK-A), a novel natural diterpenoid, in nasopharyngeal carcinoma 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2013, 卷号: 11, 期号: 1, 页码: 200
作者:  Zou, Qing-Feng;  Du, Ji-Ke;  Zhang, Hua;  Wang, Hong-Bo;  Hu, Ze-Dong;  Chen, Shu-Peng;  Du, Yong;  Li, Man-Zhi;  Xie, Dan;  Zou, Juan;  Sun, Han-Dong;  Pu, Jian-Xin;  Zeng, Mu-Sheng
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Longikaurin a (Lk-a)  Apoptosis  Caspase  Nasopharyngeal Carcinoma  
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
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One Of The Major compOnents Isolated From The Traditional  2-methyl-1  Chinese Medicine Rubia Yunnanensis  3  Exhibited Inhibitory Activity On The proliferatiOn Of Several  6-trihydroxy-9  HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay  10-anthraquinone (Mta)  And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle  Arrest In Human Cervical carcInoma Hela Cells. Further  Mta Was Found To Induce apopTosis Of Hela Cells  Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And  Release Of Cytochrome c Into The Cytosol  Which Caused The Cleavage Of Caspase And Poly(Adp-ribose)  Polymerase And Finally Triggered The Apoptosis. furThermore  The P53/p21/cdc2-cyclin B1 Signaling Was  Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of  Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused  The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of  R. Yunnanensis  a Folk Anti-cancer Herb Used In Yunnan  China.  
Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediated G0/G1 cell cycle arrest and apoptosis 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2013, 卷号: 132, 期号: 3, 页码: 707-716
作者:  Kan, Winnie Lai Ting;  Yin, Chun;  Xu, Hong Xi;  Xu, Gang;  To, Kenneth Kin Wah;  Cho, Chi Hin;  Rudd, John Anthony;  Lin, Ge
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Guttiferone k  Anti-tumor  Colon Cancer  Apoptosis  Cell Cycle  
A new anticancer compound, Oblongifolin C, inhibits tumor growth and promotes apoptosis in HeLa cells through bax activation 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2012, 卷号: 131, 期号: 6, 页码: 1445-1454
作者:  Feng, Chao;  Zhou, Li-Ying;  Yu, Ting;  Xu, Gang;  Tian, Hong-Lei;  Xu, Jin-Jie;  Xu, Hong-Xi;  Luo, Kathy Qian
Adobe PDF(1707Kb)  |  收藏  |  浏览/下载：342/92  |  提交时间：2012/11/30
Anticancer Drug Discovery  Herbal Medicine  Oblongifolin c  Apoptosis  Bax  
Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 卷号: 262, 期号: 1, 页码: 80-90
作者:  Li, Lin;  Yue, Grace G. L.;  Lau, Clara B. S.;  Sun, Handong;  Fung, Kwok Pui;  Leung, Ping Chung;  Han, Quanbin;  Leung, Po Sing
Adobe PDF(2066Kb)  |  收藏  |  浏览/下载：292/63  |  提交时间：2014/04/02
Eriocalyxin b  Pancreatic Cancer  Apoptosis  Cell Cycle Arrest  P53