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Nonasaccharide Inhibits Intrinsic Factor Xase Complex by Binding to Factor IXa and Disrupting Factor IXa-Factor VIIIa Interactions 期刊论文
THROMBOSIS AND HAEMOSTASIS, 2019, 卷号: 119, 期号: 5, 页码: 705-715
作者:  Xiao, Chuang;  Zhao, Longyan;  Gao, Na;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(740Kb)  |  收藏  |  浏览/下载：237/61  |  提交时间：2019/06/24
nonasaccharide from fucosylated glycosaminoglycan  intrinsic factor Xase complex  factor IXa  anticoagulant  
Precise structures of fucosylated glycosaminoglycan and its oligosaccharides as novel intrinsic factor Xase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 423-435
作者:  Shang, Feineng;  Gao, Na;  Yin, Ronghua;  Lin, Lisha;  Xiao, Chuang;  Zhou, Lutan;  Li, Zi;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(3117Kb)  |  收藏  |  浏览/下载：257/76  |  提交时间：2018/05/08
Glycosaminoglycan  Oligosaccharide  Anticoagulant  Intrinsic Factor Xase  
Interactions between depolymerized fucosylated glycosaminoglycan and coagulation proteases or inhibitors 期刊论文
THROMBOSIS RESEARCH, 2016, 卷号: 146, 页码: 59-68
作者:  Xiao, Chuang;  Lian, Wu;  Zhou, Lutan;  Gao, Na;  Xua, Li;  Chen, Jun;  Wu, Mingyi;  Peng, Wenlie;  Zhao, Jinhua
浏览  |  Adobe PDF(5739Kb)  |  收藏  |  浏览/下载：356/91  |  提交时间：2017/01/05
Fucosylated Glycosaminoglycan  Coagulation Proteases  Biolayer Interferometry  Binding Kinetics  Structure-activity Relationship  
beta-Eliminative depolymerization of the fucosylated chondroitin sulfate and anticoagulant activities of resulting fragments 期刊论文
CARBOHYDRATE POLYMERS, 2015, 卷号: 127, 页码: 427-437
作者:  Gao, Na;  Lu, Feng;  Xiao, Chuang;  Yang, Lian;  Chen, Jun;  Zhou, Kai;  Wen, Dandan;  Li, Zi;  Wu, Mingyi;  Jiang, Jianmin;  Liu, Guangming;  Zhao, Jinhua;  Liu,GM (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,132 Lanhei Rd,Kunming 650201,Yunnan,Peoples R China.;  lgm13330555378@126.com;  zhao.jinhua@yahoo.com
浏览  |  Adobe PDF(2985Kb)  |  收藏  |  浏览/下载：600/145  |  提交时间：2015/07/20
Fucosylated Chondroitin Sulfate  Benzyl Esterification  Beta-elimination  Depolymerization  Anticoagulant  
Discovery of an intrinsic tenase complex inhibitor: Pure nonasaccharide from fucosylated glycosaminoglycan 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 卷号: 112, 期号: 27, 页码: 8284-8289
作者:  Zhao, Longyan;  Wu, Mingyi;  Xiao, Chuang;  Yang, Lian;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Chen, Jun;  Chen, Jianchao;  Liu, Jikai;  Qin, Hongbo;  Zhao, Jinhua
浏览  |  Adobe PDF(1067Kb)  |  收藏  |  浏览/下载：324/44  |  提交时间：2015/12/17
Anticoagulant  Inhibitors  Oligosaccharides  Carbohydrates  Drug Discovery  
Structural Analysis and Anticoagulant Activities of the Novel Sulfated Fucan Possessing a Regular Well-Defined Repeating Unit from Sea Cucumber 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 4, 页码: 2063-2084
作者:  Wu, Mingyi;  Xu, Li;  Zhao, Longyan;  Xiao, Chuang;  Gao, Na;  Luo, Lan;  Yang, Lian;  Li, Zi;  Chen, Lingyun;  Zhao, Jinhua
浏览  |  Adobe PDF(2239Kb)  |  收藏  |  浏览/下载：299/56  |  提交时间：2015/06/29
Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2013, 卷号: 1830, 期号: 10, 页码: 4681-4691
作者:  Lian, Wu;  Wu, Mingyi;  Huang, Ning;  Gao, Na;  Xiao, Chuang;  Li, Zi;  Zhang, Zhigang;  Zheng, Yongtang;  Peng, Wenlie;  Zhao, Jinhua
Adobe PDF(2650Kb)  |  收藏  |  浏览/下载：474/94  |  提交时间：2013/11/12
Glycosaminoglycan  Anti-human Immunodeficiency Virus Activity  Envelope Glycoprotein 120  Cluster Of Differentiation 4 Induced Epitope  Biolayer Interferometry  Structure-activity Relationship  
Comparison of Physicochemical Characteristics and Anticoagulant Activities of Polysaccharides from Three Sea Cucumbers 期刊论文
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 399-417
作者:  Luo, Lan;  Wu, Mingyi;  Xu, Li;  Lian, Wu;  Xiang, Jingying;  Lu, Feng;  Gao, Na;  Xiao, Chuang;  Wang, Shengmin;  Zhao, Jinhua
浏览  |  Adobe PDF(1403Kb)  |  收藏  |  浏览/下载：604/89  |  提交时间：2013/07/24
Sea Cucumber  Polysaccharide  Fucosylated Chondroitin Sulfate  Sulfated Fucan  Glucan  Anticoagulant Activity