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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：325/74  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 16
作者:  Hu, Jing;  Li, Xingren;  Tian, Weifeng;  Lu, Yanting;  Xu, Yuhui;  Wang, Fang;  Qin, Wanying;  Ma, Xiuli;  Puno, Pema-Tenzin;  Xiong, Wenyong
浏览  |  Adobe PDF(3093Kb)  |  收藏  |  浏览/下载：365/26  |  提交时间：2019/03/18
adenanthin  adipogenesis  reactive oxygen species  obesity  3T3-L1  
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
收藏  |  浏览/下载：222/0  |  提交时间：2018/07/16
Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC  
Diterpenoids from Isodon species: an update 期刊论文
NATURAL PRODUCT REPORTS, 2017, 卷号: 34, 期号: 9, 页码: 1090-1140
作者:  Liu, Miao;  Wang, Wei-Guang;  Sun, Han-Dong;  Pu, Jian-Xin
浏览  |  Adobe PDF(10292Kb)  |  收藏  |  浏览/下载：276/34  |  提交时间：2017/10/23
Ent-kaurane Diterpenoids  Japonica Var. Glaucocalyx  Nf-kappa-b  Hepatocellular-carcinoma Cells  C-h Functionalization  Dna-binding Activity  Serra Maxim. Hara  Maoecrystal-v  Abietane Diterpenoids  Chemical-constituents  
The Natural Diterpenoid Isoforretin A Inhibits Thioredoxin-1 and Triggers Potent ROS-Mediated Antitumor Effects 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 4, 页码: 926-936
作者:  Sun, Xiaoyan;  Wang, Weiguang;  Chen, Jiao;  Cai, Xueting;  Yang, Jie;  Yang, Yang;  Yan, Huaijiang;  Cheng, Xiaolan;  Ye, Juan;  Lu, Wuguang;  Hu, Chunping;  Sun, Handong;  Pu, Jianxin;  Cao, Peng
浏览  |  Adobe PDF(1370Kb)  |  收藏  |  浏览/下载：489/231  |  提交时间：2017/02/28
Eriocalyxin B, a Novel Autophagy Inducer, Exerts Anti-tumor Activity Through the Suppression of Akt/mTOR/p70S6K Signaling Pathway In breast Cancer 期刊论文
Biochemical Pharmacology, 2017, 卷号: 142, 页码: 58–70
作者:  Xunian Zhou;  Grace Gar-Lee Yue;  Andrew Man-Lok Chan;   Stephen Kwok-Wing Tsui;  Kwok-Pui Fung;   Handong Sun;  Jianxin Pu;  Clara Bik-San Lau
浏览  |  Adobe PDF(5871Kb)  |  收藏  |  浏览/下载：225/57  |  提交时间：2017/11/20
Targeting peroxiredoxin I potentiates 1,25-dihydroxyvitamin D3-induced cell differentiation in leukemia cells 期刊论文
MOLECULAR MEDICINE REPORTS, 2016, 卷号: 13, 期号: 3, 页码: 2201-2207
作者:  Wei, Wei;  Liu, Chuanxu;  Qin, Dongjun;  Song, Lili;  Xia, Li;  Lei, Hu;  Yu, Yun;  Wang, Weiwei;  Pu, Jianxin;  Sun, Handong;  Wu, Yingli;  Xu, Hanzhang;  Haw, Siguo
浏览  |  Adobe PDF(1039Kb)  |  收藏  |  浏览/下载：220/64  |  提交时间：2016/06/27
Adenanthin  1  25-dihydroxyvitamin D3  Leukemia  Peroxiredoxin i  Cell Differentiation  
Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells 期刊论文
NATURE CHEMICAL BIOLOGY, 2012, 卷号: 8, 期号: 5, 页码: 486-493
作者:  Liu, Chuan-Xu;  Yin, Qian-Qian;  Zhou, Hu-Chen;  Wu, Ying-Li;  Pu, Jian-Xin;  Xia, Li;  Liu, Wei;  Huang, Xin;  Jiang, Tao;  Wu, Ming-Xuan;  He, Li-Cai;  Zhao, Ya-Xue;  Wang, Xiao-Lin;  Xiao, Wei-Lie;  Chen, Hong-Zhuan;  Zhao, Qian;  Zhou, Ai-Wu;  Wang, Li-Shun;  Sun, Han-Dong;  Chen, Guo-Qiang
浏览  |  Adobe PDF(1434Kb)  |  收藏  |  浏览/下载：685/199  |  提交时间：2012/06/07
Cimicifuga Foetida  Cycloartane  Cytotoxicity  Ranunculaceae  Breast-cancer Cells  Crude Drug Shoma  Racemosa Extract  Simplex Wormsk  Cyclolanostanol Xylosides  Triterpene Glycosides  Chemical-constituents  Prostate-cancer  Aerial Parts  Black Cohosh