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Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367
作者:  Yang, Xiao-Tong;  Li, Tian-Ze;  Geng, Chang-An;  Liu, Pei;  Chen, Ji-Jun
Adobe PDF(1348Kb)  |  收藏  |  浏览/下载：33/8  |  提交时间：2024/04/30
(20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol  alpha-glucosidase inhibitors  PTP1B inhibitors  Enzyme kinetics  TYROSINE-PHOSPHATASE 1B  DIABETES-MELLITUS  EPIDEMIOLOGY  
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Huang,Xiao-Yan;  Zhang,Xue-Mei;  Guo,Yuan-Qiang;  Geng,Chang-An
Adobe PDF(2762Kb)  |  收藏  |  浏览/下载：141/59  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols B-1-B-15  Natural products  Structure elucidation  Biological activity  TYROSINE-PHOSPHATASE 1B  GLYCOGEN-PHOSPHORYLASE  ALPHA-GLUCOSIDASE  ABSOLUTE-CONFIGURATION  STRUCTURE ELUCIDATION  DUAL INHIBITION  SEEDS  CONSTITUENT  DERIVATIVES  CHALCONE  
Chemical profiling and antidiabetic potency of Paeonia delavayi: Comparison between different parts and constituents 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 113998
作者:  Huang,Qian;  Chen,Ji-Jun;  Pan,Yang;  He,Xiao-Feng;  Wang,Yuan;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(2388Kb)  |  收藏  |  浏览/下载：69/10  |  提交时间：2022/04/02
Paeonia delavayi  Chemical comparison  LCMS analyses  Antidiabetic effects  PTP1B/TCPTP selective inhibitors  LIQUID-CHROMATOGRAPHY  MULTIPLE CONSTITUENTS  RAPID IDENTIFICATION  GLYCOSIDES  ROOT  DERIVATIVES  TARGETS  CAPSULE  L.  
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(5184Kb)  |  收藏  |  浏览/下载：92/24  |  提交时间：2022/04/02
Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID  
Diarylheptanoid-chalcone hybrids with PTP1B and alpha-glucosidase dual inhibition from Alpinia katsumadai 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104683
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(2223Kb)  |  收藏  |  浏览/下载：131/53  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols A(1)-A(16)  PTP1B/TCPTP selective inhibitors  alpha-glucosidase inhibitors  Antidiabetic effects  THEORETICAL CALCULATION  ABSOLUTE-CONFIGURATION  SEEDS  BLEPHAROCALYXINS  ADDUCT  MOIETY  
Amomutsaokols A-K, diarylheptanoids from Amomum tsao-ko and their alpha-glucosidase inhibitory activity 期刊论文
PHYTOCHEMISTRY, 2020
作者:  He, Xiao-Feng;  Wang, Hui-Mei;  Geng, Chang-An;  Hu, Jing;  Zhang, Xue-Mei;  Guo, Yuan-Qiang;  Chen, Ji-Jun
浏览  |  Adobe PDF(3949Kb)  |  收藏  |  浏览/下载：146/48  |  提交时间：2021/01/05
Tsaokopyranols A-M, 2,6-epoxydiarylheptanoids from Amomum tsao-ko and their alpha-glucosidase inhibitory activity 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  He, Xiao-Feng;  Zhang, Xu-Ke;  Geng, Chang-An;  Hu, Jing;  Zhang, Xue-Mei;  Guo, Yuan-Qiang;  Chen, Ji-Jun
浏览  |  Adobe PDF(2442Kb)  |  收藏  |  浏览/下载：114/37  |  提交时间：2021/01/05
ent-Labdane and ent-kaurane diterpenoids from Chelonopsis odontochila with alpha-glucosidase inhibitory activity 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  Deng, Zhen-Tao;  Chen, Ji-Jun;  Geng, Chang-An
浏览  |  Adobe PDF(3607Kb)  |  收藏  |  浏览/下载：130/39  |  提交时间：2021/01/05
Antidiabetic Stilbenes from Peony Seeds with PTP1B, alpha-Glucosidase, and DPPIV Inhibitory Activities 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 24, 页码: 6765-6772
作者:  Zhang,Chen-Chen;  Geng,Chang-An;  Huang,Xiao-Yan;  Zhang,Xue-Mei;  Chen,Ji-Jun
浏览  |  Adobe PDF(3231Kb)  |  收藏  |  浏览/下载：115/42  |  提交时间：2020/04/02
Chepraecoxins A-G, ent-Kaurane Diterpenoids with alpha-Glucosidase Inhibitory Activities from Chelonopsis praecox 期刊论文
FITOTERAPIA, 2019, 卷号: 132, 页码: 60-67
作者:  Deng, Zhen-Tao;  Geng, Chang-An;  Yang, Tong-Hua;  Xiang, Chun-Lei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1349Kb)  |  收藏  |  浏览/下载：236/53  |  提交时间：2019/03/18
Chelonopsis praecox  chepraecoxins A-G  ent-kaurane diterpenoids  alpha-glucosidase