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The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
作者:  C Pergola;  J Gerstmeier;  B Monch;  B Çaliskan;  S Luderer;  C Weinige;  D Barz;  J Maczewsky;  S Pace;  A Rossi;  L Sautebin;  E Banoglu;  O Werz
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：301/1  |  提交时间：2017/07/24
Pharmacological characterizationof tachykinin tetrabranched derivatives 期刊论文
出版物, 3111, 期号: 0, 页码: 1-36
作者:  Chiara Ruzza;  Anna Rizzi;  Davide Malfacini;  Maria Camilla Cerlesi;  Federica Ferrari;  Erika Marzola;  Caterina Ambrosio;  Cristina Gro;  Salvadori Severo;  Tommaso Costa;  Girolamo Calo;  Remo Guerrini
Adobe PDF(1277Kb)  |  收藏  |  浏览/下载：123/1  |  提交时间：2017/07/24
Tachykinins  Substance p  Pwt2-sp  Nk1 Receptor  Calcium Mobilization  Bioluminescence Resonance Energy Transfer  Guinea Pig Ileum  Rat Urinary Bladder  Nociceptive Behaviour Induced By Spinal Substance p  Mice  
Structural and mechanistic basis of penicillin-bindingprotein inhibition by lactivicins 期刊论文
NATURE CHEMICAL BIOLOGY, 3111, 期号: 0, 页码: 1—5
作者:  Pauline Macheboeuf;  Delphine S Fischer;  Tom Brown Jr;  Astrid Zervosen;  Andre´Luxen;  Bernard Joris;  Andrea Dessen;  Christopher J Schofield
Adobe PDF(425Kb)  |  收藏  |  浏览/下载：103/1  |  提交时间：2017/07/21
Phyllanthacidoid U: a new N-glycosyl norbisabolane sesquiterpene from Phyllanthus acidus (L.) skeels 期刊论文
NATURAL PRODUCT RESEARCH, 2020, 页码: 8
作者:  Xin, Ying;  Xu, Min;  Wang, Ya-Feng;  Zheng, Xiao-Hong;  Zhu, Hong-Tao;  Wang, Dong;  Yang, Chong-Ren;  Zhang, Ying-Jun
收藏  |  浏览/下载：170/0  |  提交时间：2020/03/18
Phyllanthus acidus  phyllanthacidoid U  norbisabolane sesquiterpenoid  amide  
Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts 期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
作者:  Yang, Jun-Li;  Ma, Yong-Hui;  Li, Yan-Hua;  Zhang, Yi-Peng;  Tian, Hong-Chang;  Huang, Yuan-Cheng;  Li, Yan;  Chen, Wen;  Yang, Li-Juan
浏览  |  Adobe PDF(2215Kb)  |  收藏  |  浏览/下载：239/52  |  提交时间：2020/03/18
Homology modeling and 3D-QSAR study of benzhydrylpiperazine delta opioid receptor agonists 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 83, 页码: 9
作者:  Pan, Chenling;  Meng, Hao;  Zhang, Shuqun;  Zuo, Zhili;  Shen, Yuehai;  Wang, Liangliang;  Chang, Kwen-Jen
浏览  |  Adobe PDF(1542Kb)  |  收藏  |  浏览/下载：287/74  |  提交时间：2020/03/18
delta opioid receptor agonists  3D-QSAR  Homology modeling  Molecular dynamics simulation  Molecular docking  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：203/31  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Flavipesines A and B and Asperchalasines E-H: Cytochalasans and Merocytochalasans from Aspergillus flavipes 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 11, 页码: 2994-3001
作者:  Zhang, Xiaotian;  Yang, Lu;  Wang, Wenjing;  Wu, Zhaodi;  Wang, Jianping;  Sun, Weiguang;  Li, Xiao-Nian;  Chen, Chunmei;  Zhu, Hucheng;  Zhang, Yonghui
浏览  |  Adobe PDF(1885Kb)  |  收藏  |  浏览/下载：142/23  |  提交时间：2020/03/18
A new p-terphenyl derivative from the fruiting bodies of Sarcodon imbricatus (L.) P. Karst 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 页码: 7
作者:  Zhang, Feng-Ming;  Wang, Yue-Hu;  Zhao, Ping;  Yu, Fu-Qiang
浏览  |  Adobe PDF(1038Kb)  |  收藏  |  浏览/下载：111/18  |  提交时间：2020/03/26
Sarcodon imbricatus  terphenyls  cytotoxicity  
Melotenuines A-E, cytotoxic monoterpenoid indole alkaloids from Melodinus tenuicaudatus 期刊论文
FITOTERAPIA, 2019, 卷号: 138, 页码: 7
作者:  Liu, Jian-Wen;  Huo, Zong-Qing;  Zhao, Qian;  Hao, Xiao-Jiang;  He, Hong-Ping;  Zhang, Yu
浏览  |  Adobe PDF(435Kb)  |  收藏  |  浏览/下载：367/222  |  提交时间：2020/03/18
Melodinus tenuicaudatus  Monoterpenoid indole alkaloids  Melotenuines A-E  Aspidosperma-meloscandonine type