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Anti-BACE1 and anti-AchE activities of undescribed spiro-dioxolane-containing meroterpenoids from the endophytic fungus Aspergillus terreus Thom 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 165, 页码: 8
作者:  Qi, Changxing;  Zhou, Qun;  Gao, Weixi;  Liu, Mengting;  Chen, Chunmei;  Li, Xiao-Nian;  Lai, Yongji;  Zhou, Yuan;  Li, Dongyan;  Hu, Zhengxi;  Zhu, Hucheng;  Zhang, Yonghui
浏览  |  Adobe PDF(1128Kb)  |  收藏  |  浏览/下载：302/158  |  提交时间：2019/10/14
Aspergillus terreus Thom  endophytic fungus  3,5-Dimethylorsellinic acid-based meroterpenoid  Adducts  Alzheimer's disease  
Novel Sodium Channel Inhibitor From Leeches 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 页码: 186
作者:  Wang, Gan;  Long, Chengbo;  Liu, Weihui;  Xu, Cheng;  Zhang, Min;  Li, Qiong;  Lu, Qiumin;  Meng, Ping;  Li, Dongsheng;  Rong, Mingqiang;  Sun, Zhaohui;  Luo, Xiaodong;  Lai, Ren
浏览  |  Adobe PDF(1661Kb)  |  收藏  |  浏览/下载：264/50  |  提交时间：2018/05/08
Leech Therapy  Blood-sucking  Sodium Channel  Pain  Analgesia  
Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
浏览  |  Adobe PDF(5724Kb)  |  收藏  |  浏览/下载：396/45  |  提交时间：2017/12/18
Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 11, 页码: 4680-4692
作者:  Qu, Chunrong;  Ding, Mingmin;  Zhu, Yingmin;  Lu, Yungang;  Du, Juan;  Miller, Melissa;  Tian, Jinbin;  Zhu, Jinmei;  Xui, Jian;  Wen, Meng;  Er-Bu, Aga;  Wan, Jule;  Xiao, Yuling;  Wu, Meng;  McManus, Owen B.;  Li, Min;  Wu, Jilin;  Luo, Huai-Rong;  Cao, Zhengyu;  Shen, Bing;  Wang, Hongbo;  Zhu, Michael X.;  Hong, Xuechuan
浏览  |  Adobe PDF(1969Kb)  |  收藏  |  浏览/下载：222/79  |  提交时间：2017/08/29
Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 37, 页码: 58995-59005
作者:  Wu, Jingjing;  Lei, Hu;  Zhang, Jinfu;  Chen, Xiangyun;  Tang, Caixia;  Wang, Weiwei;  Xu, Hanzhang;  Xiao, Weilie;  Gu, Wenli;  Wu, Yingli
浏览  |  Adobe PDF(2389Kb)  |  收藏  |  浏览/下载：158/38  |  提交时间：2017/01/05
Momordin Ic  Senp1  Sumoylation  Proliferation  Prostate Cancer  
Synthesis and antitumor activity of novel N-substituted carbazole imidazolium salt derivatives 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Liu, Lan-Xiang;  Wang, Xue-Quan;  Zhou, Bei;  Yang, Li-Juan;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(1438Kb)  |  收藏  |  浏览/下载：1605/809  |  提交时间：2016/01/19
Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-kappa B Activation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 11, 页码: 4749-4757
作者:  Zhao, Yu;  Su, Jia;  Goto, Masuo;  Morris-Natschke, Susan L.;  Li, Yan;  Zhao, Qin-Shi;  Yao, Zhu-Jun;  Lee, Kuo-Hsiung
Adobe PDF(531Kb)  |  收藏  |  浏览/下载：325/72  |  提交时间：2013/10/16
Natural-products  Biological-activity  Cancer-therapy  Paclitaxel  Taxol  Resistance  Drugs  Chemotherapy  Parthenolide  Brevifoliol  
The endoperoxide ascaridol shows strong differential cytotoxicity in nucleotide excision repair-deficient cells 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 卷号: 259, 期号: 3, 页码: 302-310
作者:  Abbasi, Rashda;  Efferth, Thomas;  Kuhmann, Christine;  Opatz, Till;  Hao, Xiaojiang;  Popanda, Odilia;  Schmezer, Peter
Adobe PDF(738Kb)  |  收藏  |  浏览/下载：479/169  |  提交时间：2012/06/07
Cancer Therapy  Synthetic Lethal  Traditional Chinese Medicine  Xpc  Ercc6  Csb