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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning
期刊论文
CELL REPORTS, 2019, 卷号: 28, 期号: 2, 页码: 541-+
作者:
Ma, Pengcheng
;
Song, Ning-Ning
;
Li, Yongxin
;
Zhang, Qiong
;
Zhang, Lei
;
Zhang, Longlong
;
Kong, Qinghua
;
Ma, Li
;
Yang, Xiangcai
;
Ren, Biyu
;
Li, Chaocui
;
Zhao, Xudong
;
Li, Yan
;
Xu, Ying
;
Gao, Xiang
;
Ding, Yu-Qiang
;
Mao, Bingyu
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Adobe PDF(5547Kb)
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浏览/下载:273/58
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提交时间:2019/08/19
Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:
Shao, Li-Dong
;
Su, Jia
;
Ye, Baixin
;
Liu, Jiang-Xin
;
Zuo, Zhi-Li
;
Li, Yan
;
Wang, Yue-Ying
;
Xia, Chengfeng
;
Zhao, Qin-Shi
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Adobe PDF(5724Kb)
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浏览/下载:396/45
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提交时间:2017/12/18
Star-PAP, a poly(A) polymerase, functions as a tumor suppressor in an orthotopic human breast cancer model
期刊论文
CELL DEATH & DISEASE, 2017, 卷号: 8, 期号: 1, 页码: e2582
作者:
Yu, C.
;
Gong, Y.
;
Zhou, H.
;
Wang, M.
;
Kong, L.
;
Liu, J.
;
An, T.
;
Zhu, H.
;
Li, Y.
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Adobe PDF(3022Kb)
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浏览/下载:207/47
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提交时间:2017/04/19
The Ubiquitin Ligase RNF220 Enhances Canonical Wnt Signaling through USP7-Mediated Deubiquitination of beta-Catenin
期刊论文
MOLECULAR AND CELLULAR BIOLOGY, 2014, 卷号: 34, 期号: 23, 页码: 4355-4366
作者:
Ma, Pengcheng
;
Yang, Xiangcai
;
Kong, Qinghua
;
Li, Chaocui
;
Yang, Shuangjuan
;
Li, Yan
;
Mao, Bingyu
;
Mao,BY (reprint author),Kunming Inst Zool,State Key Lab Genet Resources & Evolut,Kunming,Peoples R China.
;
mao@mail.kiz.ac.cn
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Adobe PDF(1708Kb)
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浏览/下载:298/62
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提交时间:2015/01/20
Stem-cell Fate
Shoot Apical Meristem
Arabidopsis Shoot
Crabs-claw
Nectary Development
Expression
Thaliana
Family
Loop
Polarity
Iayabby2
Ad-abaxial Polarity
Incarvillea Arguta
Arabidopsis Thaliana
Identification and validation of p50 as the cellular target of eriocalyxin B
期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:
Kong, Ling-Mei
;
Deng, Xu
;
Zuo, Zhi-Li
;
Sun, Han-Dong
;
Zhao, Qin-Shi
;
Li, Yan
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Adobe PDF(3014Kb)
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浏览/下载:303/80
  |  
提交时间:2015/06/17
Erib
Activity-based Probes
P50
Nf-kappa b Signaling
Apoptosis
Synthesis and cytotoxic activity of novel hybrid compounds between 2-alkylbenzofuran and imidazole
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 3, 页码: 1599-1611
作者:
Wan, Wei-Chao
;
Chen, Wen
;
Liu, Lan-Xiang
;
Li, Yan
;
Yang, Li-Juan
;
Deng, Xiao-Yan
;
Zhang, Hong-Bin
;
Yang, Xiao-Dong
Adobe PDF(509Kb)
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浏览/下载:808/532
  |  
提交时间:2014/04/09
Hybrid Compound
Benzofuran
Imidazole
Cytotoxic Activity
Structure-activity Relationships
Molecular Docking
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells
期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:
Zeng, Guang-Zhi
;
Fan, Jun-Ting
;
Xu, Jun-Ju
;
Li, Yan
;
Tan, Ning-Hua
Adobe PDF(6299Kb)
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浏览/下载:282/50
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提交时间:2015/05/14
One Of The Major compOnents Isolated From The Traditional
2-methyl-1
Chinese Medicine Rubia Yunnanensis
3
Exhibited Inhibitory Activity On The proliferatiOn Of Several
6-trihydroxy-9
HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay
10-anthraquinone (Mta)
And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle
Arrest In Human Cervical carcInoma Hela Cells. Further
Mta Was Found To Induce apopTosis Of Hela Cells
Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And
Release Of Cytochrome c Into The Cytosol
Which Caused The Cleavage Of Caspase And Poly(Adp-ribose)
Polymerase And Finally Triggered The Apoptosis. furThermore
The P53/p21/cdc2-cyclin B1 Signaling Was
Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of
Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused
The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of
R. Yunnanensis
a Folk Anti-cancer Herb Used In Yunnan
China.
Drug-mediated inhibition of Fli-1 for the treatment of leukemia
期刊论文
BLOOD CANCER JOURNAL, 2012, 卷号: 2, 页码: e54
作者:
Li, Y-J
;
Zhao, X.
;
Vecchiarelli-Federico, L. M.
;
Li, Y.
;
Datti, A.
;
Cheng, Y.
;
Ben-David, Y.
Adobe PDF(618Kb)
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浏览/下载:254/54
  |  
提交时间:2012/06/07
Erythroleukemia
Fli-1
Drug Inhibition
The functional roles of lipid rafts in T-Cell activation, immune diseases and HIV infection and prevention
期刊论文
CELLULAR & MOLECULAR IMMUNOLOGY, 2008, 卷号: 5, 期号: 1, 页码: 1-7
作者:
Luo, Cheng
;
Wang, Kou
;
Liu, Dequan
;
Li, Yan
;
Zhao, Qinshi
Adobe PDF(909Kb)
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浏览/下载:337/120
  |  
提交时间:2011/11/24
Lipid Raft
Liquid Ordered Phase
Liquid Crystal Phase
Cholesterol
Virus Assembly