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Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 11
作者:  Liu, Tangjingjun;  Xia, Lei;  Yao, Yao;  Yan, Chen;  Fan, Yanhua;  Gajendran, Babu;  Yang, Jue;  Li, You-Jun;  Chen, Juan;  Filmus, Jorge;  Spaner, David E.;  Zacksenhaus, Eldad;  Hao, Xiaojiang;  Ben-David, Yaacov
Adobe PDF(2055Kb)  |  收藏  |  浏览/下载：276/38  |  提交时间：2019/04/15
Integrating transcriptome and microRNA analysis identifies genes and microRNAs for AHO-induced systemic acquired resistance in N-tabacum 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 12504
作者:  Chen, Yongdui;  Dong, Jiahong;  Bennetzen, Jeffrey L.;  Zhong, Micai;  Yang, Jun;  Zhang, Jie;  Li, Shunlin;  Hao, Xiaojiang;  Zhang, Zhongkai;  Wang, Xuewen
Adobe PDF(3093Kb)  |  收藏  |  浏览/下载：345/67  |  提交时间：2017/10/23
Plant Innate Immunity  Acibenzolar-s-methyl  Flue-cured Tobacco  Salicylic-acid  Small Rnas  Stress Responses  Expression  Arabidopsis  Target  Mirna  
Rapid synthesis of ismine, a bioactive amaryllidaceae alkaloid 期刊论文
JOURNAL OF CHEMICAL RESEARCH, 2017, 期号: 4, 页码: 202-204
作者:  Guo, Jing-jing;  Yang, Bi-juan;  Jing, Chen-xu;  Chen, Duo-zhi;  Hao, Xiao-jiang
Adobe PDF(192Kb)  |  收藏  |  浏览/下载：187/29  |  提交时间：2018/05/08
Amaryllidaceae Alkaloid  Palladium Catalyst  Aryl-aryl Coupling  N-aryl Coupling  
Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/beta-catenin transcriptional activity 期刊论文
CELL DISCOVERY, 2017, 卷号: 3, 页码: 17003
作者:  He, Xiaoli;  Zhang, Wenjuan;  Yan, Chen;  Nie, Fen;  Li, Chen;  Liu, Xiaofen;  Fei, Cong;  Li, Shengdi;  Song, Xiaomin;  Jia, Yingying;  Zeng, Rong;  Wu, Dianqing;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
Adobe PDF(3775Kb)  |  收藏  |  浏览/下载：151/37  |  提交时间：2017/12/18
Carf  Chemical Biology  Nc043  Small Molecule  Wnt Signaling  
Protein kinase C controls lysosome biogenesis independently of mTORC1 期刊论文
NATURE CELL BIOLOGY, 2016, 卷号: 18, 期号: 10, 页码: 1065-1077
作者:  Li, Yang;  Xu, Meng;  Ding, Xiao;  Yan, Chen;  Song, Zhiqin;  Chen, Lianwan;  Huang, Xiahe;  Wang, Xin;  Jian, Youli;  Tang, Guihua;  Tang, Changyong;  Di, Yingtong;  Mu, Shuzhen;  Liu, Xuezhao;  Liu, Kai;  Li, Ting;  Wang, Yingchun;  Miao, Long;  Guo, Weixiang;  Hao, Xiaojiang;  Yang, Chonglin
Adobe PDF(4637Kb)  |  收藏  |  浏览/下载：564/150  |  提交时间：2016/12/21
Synthesis of 4-ethyl-5-methyl-5,6-dihydrophenanthridine-8,9-diol as the key intermediate of potent agonists of the Wnt signalling pathway 期刊论文
JOURNAL OF CHEMICAL RESEARCH, 2015, 期号: 4, 页码: 247-250
作者:  Jing, Chen-xu;  Cai, Jie-yun;  Zhang, Yu;  Chen, Duo-zhi;  Hao, Xiao-jiang
Adobe PDF(418Kb)  |  收藏  |  浏览/下载：144/51  |  提交时间：2016/01/19
Phenanthridin  Palladium Catalyst  Aryl-aryl Coupling  N-aryl Coupling  
Asymmetric Synthesis of the Tricyclic Core of Calyciphylline A-Type Alkaloids via Intramolecular [3+2] Cycloaddition 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 4, 页码: 1076-1079
作者:  Wang, Lu;  Xu, Chen;  Chen, Li;  Hao, Xiaojiang;  Wang, David Zhigang
Adobe PDF(389Kb)  |  收藏  |  浏览/下载：285/64  |  提交时间：2014/04/09
Beta-hydroxy Ketones  Nitrile Oxide Cycloaddition  Daphniphyllum Alkaloids  Tetracyclic Core  Daphnilactone-b  Ring-system  Construction  Reduction  Delta-2-isoxazolines  Route  
A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2013, 卷号: 63, 期号: SI, 页码: 485-494
作者:  Liu, Jinhua;  Mu, Chenglong;  Yue, Wen;  Li, Jie;  Ma, Biao;  Zhao, Lixia;  Liu, Lei;  Chen, Quan;  Yan, Chen;  Liu, Haiyang;  Hao, Xiaojiang;  Zhu, Yushan
浏览  |  Adobe PDF(2679Kb)  |  收藏  |  浏览/下载：314/61  |  提交时间：2013/10/16
Thioredoxin Reductase  Bim  Ros  Apoptosis  Cancer  
Inhibition of 11 beta-HSD1 by Tetracyclic Triterpenoids from Euphorbia kansui 期刊论文
MOLECULES, 2012, 卷号: 17, 期号: 10, 页码: 11826-11838
作者:  Guo, Jie;  Zhou, Li-Yan;  He, Hong-Ping;  Leng, Ying;  Yang, Zhen;  Hao, Xiao-Jiang
Adobe PDF(1631Kb)  |  收藏  |  浏览/下载：311/61  |  提交时间：2013/01/22
Tetracyclic Triterpenoids  Euphorbia Kansui  Inhibition Of 11 Beta-hsd1  Docking  
Tackling Reactivity and Selectivity within a Strained Architecture: Construction of the [6-6-5-7] Tetracyclic Core of Calyciphylline Alkaloids 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2012, 卷号: 77, 期号: 14, 页码: 6307-6313
作者:  Xu, Chen;  Wang, Lu;  Hao, Xiaojiang;  Wang, David Zhigang
Adobe PDF(393Kb)  |  收藏  |  浏览/下载：285/76  |  提交时间：2012/09/03
1st Total Syntheses  Daphniphyllum-calycinum  Longeracemosum  Fragmentation