Rapid synthesis of ismine, a bioactive amaryllidaceae alkaloid

doi:10.3184/174751917X14894997017496

	Rapid synthesis of ismine, a bioactive amaryllidaceae alkaloid
	Guo, Jing-jing 1,2; Yang, Bi-juan 2,3; Jing, Chen-xu 2; Chen, Duo-zhi 2; Hao, Xiao-jiang2
	2017-04-01
发表期刊	JOURNAL OF CHEMICAL RESEARCH
ISSN	1747-5198
期号	4 页码:202-204
摘要	Ismine (6-[2-( methylamino) phenyl]-1,3-benzodioxole-5-methanol, 1), a biologically active alkaloid, has been synthesised by a rapid and simple four-step sequence. This synthesis involved a consecutive aryl-aryl and N-aryl coupling, leading to a phenanthridine derivative in a one-pot sequence, which employed a palladium catalyst and trifurylphosphine as the ligand. This synthesis gave an overall yield of 23%.
关键词	Amaryllidaceae Alkaloid Palladium Catalyst Aryl-aryl Coupling N-aryl Coupling
DOI	10.3184/174751917X14894997017496
语种	英语
WOS记录号	WOS:000416040700004
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/60632
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Yunnan Univ Tradit Chinese Med, Coll Tradit Chinese Med, Kunming 650500, Yunnan, Peoples R China 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China 3.Yunnan Univ, Sch Chem Sci & Technol, Kunming 650000, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Guo, Jing-jing,Yang, Bi-juan,Jing, Chen-xu,et al. Rapid synthesis of ismine, a bioactive amaryllidaceae alkaloid[J]. JOURNAL OF CHEMICAL RESEARCH,2017(4):202-204.
APA	Guo, Jing-jing,Yang, Bi-juan,Jing, Chen-xu,Chen, Duo-zhi,&Hao, Xiao-jiang.(2017).Rapid synthesis of ismine, a bioactive amaryllidaceae alkaloid.JOURNAL OF CHEMICAL RESEARCH(4),202-204.
MLA	Guo, Jing-jing,et al."Rapid synthesis of ismine, a bioactive amaryllidaceae alkaloid".JOURNAL OF CHEMICAL RESEARCH .4(2017):202-204.

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