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Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 40, 页码: 42704-42716
作者:  Luo, Xiangjian;  Yang, Lifang;  Xiao, Lanbo;  Xia, Xiaofeng;  Dong, Xin;  Zhong, Juanfang;  Liu, Ying;  Li, Namei;  Chen, Ling;  Li, Hongde;  Li, Wei;  Liu, Wenbin;  Yu, Xinfang;  Chen, Hanyong;  Tang, Min;  Weng, Xinxian;  Yi, Wei;  Bode, Ann;  Dong, Zigang;  Liu, Jikai;  Cao, Ya
浏览  |  Adobe PDF(5262Kb)  |  收藏  |  浏览/下载：219/34  |  提交时间：2016/06/27
Grifolin  Erk1/2  Dnmt1  Metastasis  
Natural products against hematological malignancies and identification of their targets 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2015, 卷号: 58, 期号: 12, 页码: 1191-1201
作者:  Xu Ying;  Liu JinBao;  Wu YingLi;  Guo QingLong;  Sun HanDong;  Chen GuoQiang
Adobe PDF(756Kb)  |  收藏  |  浏览/下载：192/31  |  提交时间：2016/05/04
Natural Products  Adenanthin  Hematological Malignancies  Target Identification  
RA-XII inhibits tumour growth and metastasis in breast tumour-bearing mice via reducing cell adhesion and invasion and promoting matrix degradation 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Leung,Hoi-Wing;  Zhao,Si-Meng;  Yue,Grace Gar-Lee;  Lee,Julia Kin-Ming;  Fung,Kwok-Pui;  Leung,Ping-Chung;  Tan,Ning-Hua;  Lau,Clara Bik-San
浏览  |  Adobe PDF(2369Kb)  |  收藏  |  浏览/下载：209/55  |  提交时间：2016/01/19
Fibulin-3 is a novel TGF-beta pathway inhibitor in the breast cancer microenvironment 期刊论文
ONCOGENE, 2015, 卷号: 34, 期号: 45, 页码: 5635-5647
作者:  Tian,H.;  Liu,J.;  Chen,J.;  Gatza,M. L.;  Blobe,G. C.
浏览  |  Adobe PDF(7351Kb)  |  收藏  |  浏览/下载：134/39  |  提交时间：2016/01/19
Skp1 in lung cancer: clinical significance and therapeutic efficacy of its small molecule inhibitors 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 33, 页码: 34953-34967
作者:  Liu,Yong-Qiang;  Wang,Xiao-Lu;  Cheng,Xin;  Lu,Yong-Zhi;  Wang,Gui-Zhen;  Li,Xin-Chun;  Zhang,Jian;  Wen,Zhe-Sheng;  Huang,Zhi-Liang;  Gao,Qin-Lei;  Yang,Li-Na;  Cheng,Yong-Xian;  Tao,Sheng-Ce;  Liu,Jinsong;  Zhou,Guang-Biao
浏览  |  Adobe PDF(2162Kb)  |  收藏  |  浏览/下载：281/65  |  提交时间：2016/01/19
Skp1  Lung Cancer  Structure-based High-throughput Virtual Screening  Inhibitors  6-o-angeloylplenolin  
A Group of ent-Kaurane Diterpenoids Inhibit Hedgehog Signaling and Induce Cilia Elongation 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 10
作者:  Jiang,Shiyou;  Du,Jiacheng;  Kong,Qinghua;  Li,Chaocui;  Li,Yan;  Sun,Handong;  Pu,Jianxin;  Mao,Bingyu
浏览  |  Adobe PDF(7288Kb)  |  收藏  |  浏览/下载：218/57  |  提交时间：2016/01/19
Synthesis and antitumor activity of novel N-substituted carbazole imidazolium salt derivatives 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Liu, Lan-Xiang;  Wang, Xue-Quan;  Zhou, Bei;  Yang, Li-Juan;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(1438Kb)  |  收藏  |  浏览/下载：1561/807  |  提交时间：2016/01/19
GQ5 Hinders Renal Fibrosis in Obstructive Nephropathy by Selectively Inhibiting TGF-beta-Induced Smad3 Phosphorylation 期刊论文
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2015, 卷号: 26, 期号: 8, 页码: 1827-1838
作者:  Ai, Jun;  Nie, Jing;  He, Jiangbo;  Guo, Qin;  Li, Mei;  Lei, Ying;  Liu, Youhua;  Zhou, Zhanmei;  Zhu, Fengxin;  Liang, Min;  Cheng, Yongxian;  Hou, Fan Fan
浏览  |  Adobe PDF(3032Kb)  |  收藏  |  浏览/下载：207/42  |  提交时间：2016/01/19
The role of targeting kinase activity by natural products in cancer chemoprevention and chemotherapy (Review) 期刊论文
ONCOLOGY REPORTS, 2015, 卷号: 34, 期号: 2, 页码: 547-554
作者:  Luo, Xiangjian;  Yu, Xinfang;  Liu, Sufang;  Deng, Qipan;  Liu, Xiaolan;  Peng, Songling;  Li, Hongde;  Liu, Jikai;  Cao, Ya
浏览  |  Adobe PDF(755Kb)  |  收藏  |  浏览/下载：356/171  |  提交时间：2015/12/17
Natural Products  Grifolin  Neoalbaconol  Epigallocatechin-3-gallate  Cancer Prevention  
Cyclopeptide RA-V inhibits cell adhesion and invasion in both estrogen receptor positive and negative breast cancer cells via PI3K/AKT and NF-kappa B signaling pathways 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2015, 卷号: 1853, 期号: 8, 页码: 1827-1840
作者:  Leung, Hoi-Wing;  Wang, Zhe;  Yue, Grace Gar-Lee;  Zhao, Si-Meng;  Lee, Julia Kin-Ming;  Fung, Kwok-Pui;  Leung, Ping-Chung;  Lau, Clara Bik-San;  Tan, Ning-Hua;  Lau,CBS (reprint author),Chinese Univ Hong Kong,Inst Chinese Med,Shatin,Hong Kong,Peoples R China.;  claralau@cuhk.edu.hk;  nhtan@mail.kib.ac.cn
浏览  |  Adobe PDF(2434Kb)  |  收藏  |  浏览/下载：299/48  |  提交时间：2015/07/20
Cyclopeptide  Cell Adhesion  Cell Invasion  Metastasis  Breast Cancer