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Natural product sciences: an integrative approach to the innovations of plant natural products 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2020
作者:  Shen, Yuemao;  Hao, Xiaojiang
Adobe PDF(4992Kb)  |  收藏  |  浏览/下载：99/14  |  提交时间：2021/01/05
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：312/37  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Design, Synthesis, and Structural Optimization of Lycorine-Derived Phenanthridine Derivatives as Wnt/beta-Catenin Signaling Pathway Agonists 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 1, 页码: 180-188
作者:  Chen, Duo-Zhi;  Jing, Chen-Xu;  Cai, Jie-Yun;  Wu, Ji-Bo;  Wang, Sheng;  Yin, Jun -Lin;  Li, Xiao-Nian;  Li, Lin;  Hao, Xiao-Jiang
Adobe PDF(3043Kb)  |  收藏  |  浏览/下载：310/73  |  提交时间：2016/06/27
Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Chen,Duozhi;  Cai,Jieyun;  Cheng,Junjun;  Jing,Chenxu;  Yin,Junlin;  Jiang,Jiandong;  Peng,Zonggen;  Hao,Xiaojiang
浏览  |  Adobe PDF(833Kb)  |  收藏  |  浏览/下载：210/77  |  提交时间：2016/01/19
Isoquinoline alkaloids from Zanthoxylum simulans and their biological evaluation 期刊论文
JOURNAL OF ANTIBIOTICS, 2015, 卷号: 68, 期号: 4, 页码: 289-292
作者:  Yang, Sheng-Hui;  Liu, Yan-Qun;  Wang, Jun-Feng;  Wang, Yue-Hu;  Pan, Wei-Wei;  Sheng, Wen-Bing;  Cai, Rui;  Zhou, Xiao-Jiang;  Wang,JF (reprint author),Chinese Acad Sci,CAS Key Lab Trop Marine Bioresources & Ecol,Guangdong Key Lab Marine Mat Med,RNAM Ctr Marine Microbiol,South China Sea Inst Oc,Guangzhou 510301,Guangdong,Peoples R China.;  wangjunfeng@scsio.ac.cn;  gale9888@163.com
浏览  |  Adobe PDF(419Kb)  |  收藏  |  浏览/下载：260/73  |  提交时间：2015/06/29
Synthesis of 4-ethyl-5-methyl-5,6-dihydrophenanthridine-8,9-diol as the key intermediate of potent agonists of the Wnt signalling pathway 期刊论文
JOURNAL OF CHEMICAL RESEARCH, 2015, 期号: 4, 页码: 247-250
作者:  Jing, Chen-xu;  Cai, Jie-yun;  Zhang, Yu;  Chen, Duo-zhi;  Hao, Xiao-jiang
浏览  |  Adobe PDF(418Kb)  |  收藏  |  浏览/下载：140/50  |  提交时间：2016/01/19
Phenanthridin  Palladium Catalyst  Aryl-aryl Coupling  N-aryl Coupling  
Lycorine-derived phenanthridine downregulators of host Hsc70 as potential hepatitis C virus inhibitors 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2015, 卷号: 7, 期号: 5, 页码: 561-570
作者:  Chen, Duozhi;  Cai, Jieyun;  Yin, Junlin;  Jiang, Jiandong;  Jing, Chenxu;  Zhu, Yanping;  Cheng, Junjun;  Di, Yingtong;  Zhang, Yu;  Cao, Mingming;  Li, Shunlin;  Peng, Zonggen;  Hao, Xiaojiang;  Hao,XJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  haoxj@mail.kib.ac.cn
浏览  |  Adobe PDF(1560Kb)  |  收藏  |  浏览/下载：291/54  |  提交时间：2015/07/20
Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction 期刊论文
NATURE CHEMICAL BIOLOGY, 2013, 卷号: 9, 期号: 9, 页码: 579-U82
作者:  Wang, Sheng;  Yin, Junlin;  Chen, Duozhi;  Nie, Fen;  Song, Xiaomin;  Fei, Cong;  Miao, Haofei;  Jing, Changbin;  Ma, Wenjing;  Wang, Lei;  Xie, Sichun;  Li, Chen;  Zeng, Rong;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
Adobe PDF(1157Kb)  |  收藏  |  浏览/下载：615/122  |  提交时间：2013/10/16
Glycogen-synthase Kinase-3  Beta-catenin  Negative Regulator  Dix Domain  Stem-cells  In-vivo  Axin  Activation  Pathway  Phosphorylation  
Synthesis and biological evaluation of lycorine derivatives as dual inhibitors of human acetylcholinesterase and butyrylcholinesterase 期刊论文
CHEMISTRY CENTRAL JOURNAL, 2012, 卷号: 6
作者:  Wang, Yue-Hu;  Wan, Qin-Li;  Gu, Cheng-Ding;  Luo, Huai-Rong;  Long, Chun-Lin
Adobe PDF(261Kb)  |  收藏  |  浏览/下载：149/52  |  提交时间：2015/06/17
Amaryllidaceae Alkaloids  Lycorine  Acetylcholinesterase  Butyrylcholinesterase