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The opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 977-989
作者:  Yi, Shou-pu;  Kong, Qing-hong;  Li, Yu-lei;  Pan, Chen-ling;  Yu, Jie;  Cui, Ben-qiang;  Wang, Ying-fei;  Wang, Guan-lin;  Zhou, Pei-lan;  Wang, Li-li;  Gong, Ze-hui;  Su, Rui-bin;  Shen, Yue-hai;  Yu, Gang;  Chang, Kwen-jen
浏览  |  Adobe PDF(854Kb)  |  收藏  |  浏览/下载：365/75  |  提交时间：2017/08/29
Opioid Receptor  Mixed Agonist  Dpi-125  Analgesia  Respiratory Depression  Addiction  
Isocostunolide inhibited glioma stem cell by suppression proliferation and inducing caspase dependent apoptosis 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 页码: 2863-2867
作者:  Dai, Zhi;  Li, Shi-Rong;  Zhu, Pei-Feng;  Liu, Lu;  Wang, Bei;  Liu, Ya-Ping;  Luo, Xiao-Dong;  Zhao, Xu-Dong
浏览  |  Adobe PDF(2209Kb)  |  收藏  |  浏览/下载：298/66  |  提交时间：2017/07/18
Isocostunolide  Glioma Stem Cells  Cell Proliferation  Apoptosis  Colony Formation  
Metal-Free Hypervalent-Iodine-Promoted C3 Difluorination and C2 Oxidation of N-Substituted Indoles 期刊论文
ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 6, 期号: 6, 页码: 690-693
作者:  Sun, Xin;  Zhao, Xiao-Jing;  Wu, Bin
浏览  |  Adobe PDF(1337Kb)  |  收藏  |  浏览/下载：205/71  |  提交时间：2017/08/29
Difluorination  Hypervalent Compounds  Indoles  Oxidation  Oxindoles  
USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2017, 卷号: 131, 期号: 1, 页码: 29-39
作者:  An, Tao;  Gong, Yaxiao;  Li, Xue;  Kong, Lingmei;  Ma, Pengcheng;  Gong, Liang;  Zhu, Huifang;  Yu, Chunlei;  Liu, Jianmei;  Zhou, Hongyu;  Mao, Bingyu;  Li, Yan
浏览  |  Adobe PDF(3138Kb)  |  收藏  |  浏览/下载：803/149  |  提交时间：2017/04/06
Usp7 Inhibitor  Wnt Signaling  Colorectal Cancer  
(+/-)-Uncarilins A and B, Dimeric Isoechinulin-Type Alkaloids from Uncaria rhynchophylla 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 4, 页码: 959-964
作者:  Geng, Chang-An;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Hou, Bo;  Li, Tian-Ze;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1424Kb)  |  收藏  |  浏览/下载：368/93  |  提交时间：2017/08/29
Cognitive-enhancing effects of beta-sitosterol in vanadium-induced neurotoxicity in mice 期刊论文
JOURNAL OF NEUROCHEMISTRY, 2017, 卷号: 142, 页码: 238-238
作者:  Adebiyi,O.;  Olayemi,F.;  Olopade,J.;  Ning-Hua,T.
浏览  |  Adobe PDF(878Kb)  |  收藏  |  浏览/下载：170/77  |  提交时间：2017/10/23
Three New Ergot Alkaloids from the Fruiting Bodies of Xylaria nigripes (Kl.) Sacc. 期刊论文
CHEMISTRY & BIODIVERSITY, 2017, 卷号: 14, 期号: 1, 页码: e1600173
作者:  Hu, Dongbao;  Li, Ming
浏览  |  Adobe PDF(815Kb)  |  收藏  |  浏览/下载：142/53  |  提交时间：2017/04/19
Xylaria Nigripes  Ergot Alkaloids  Dft  Cetp Inhibitory Activity  
Involvement of Arachidonic Acid Metabolites Pathway and Nicotinic Acetylcholine Receptors (nAChRs) on Nicotine-induced Contractions (or Relaxations) in the Basilar Artery 期刊论文
INTERNATIONAL JOURNAL OF PHARMACOLOGY, 2017, 卷号: 13, 期号: 1, 页码: 1-10
作者:  Li, Yifan;  Luo, Dan;  Chen, Xuejiao;  Li, Jie;  Yan, Liang;  Li, Tong;  Zhao, Yingliang;  Liu, Hui;  Ji, Xu;  Ma, Xiao
浏览  |  Adobe PDF(219Kb)  |  收藏  |  浏览/下载：229/53  |  提交时间：2017/02/14
Basilar Artery  Nicotine  Vasoconstriction  Vasorelaxation  Arachidinic Acid  Nicotinic Acetylcholine Receptors (Nachrs)  Endothelium  
Two pairs of chlorine-containing phenylpropanoid enantiomers from Acorus tatarinowii 期刊论文
CHINESE CHEMICAL LETTERS, 2017, 卷号: 28, 期号: 7, 页码: 1460-1464
作者:  Lu,Yuan-Yuan;  Gong,Xue-Peng;  Xue,Yong-Bo;  Zhu,Hu-Cheng;  Li,Xiao-Nian;  Hu,Lin-Zhen;  Guan,Jian-Kun;  Zhang,Jin-Wen;  Du,Guang;  Zhang,Yong-Hui
浏览  |  Adobe PDF(522Kb)  |  收藏  |  浏览/下载：287/53  |  提交时间：2017/10/23
Absolute-configurations  Mosher Method  Sesquiterpenoids  Rhizomes  Asarone  Acorus Tatarinowii  Chlorine-containing Phenylpropanoid  Enantiomers  Antioxidant Activity  Cytotoxicity  
Bioactivity-guided synthesis of gramine derivatives as new MT1 and 5-HT1A receptors agonists 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2017, 卷号: 19, 期号: 6, 页码: 610-622
作者:  Yin, Xiu-Juan;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Geng, Chang-An;  Li, Tian-Ze;  Chen, Xing-Long;  Yang, Tong-Hua;  Zhou, Jun;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(2718Kb)  |  收藏  |  浏览/下载：351/63  |  提交时间：2017/07/10
Gramine  Melatonin Receptor  5-hydroxy-tryptamine Receptor  Agonistic Activity  Structure-activity Relationships