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题名: Three New Ergot Alkaloids from the Fruiting Bodies of Xylaria nigripes (Kl.) Sacc.
作者: Hu, Dongbao1, 2; Li, Ming1
刊名: CHEMISTRY & BIODIVERSITY
关键词: Xylaria nigripes ; Ergot alkaloids ; DFT ; CETP Inhibitory activity
英文摘要: Three new ergot alkaloids, xylanigripones A - C (1-3) together with three known compounds, agroclavine (4), 8,9-didehydro-10-hydroxy-6,8-dimethylergolin (5), and (6S)-agroclavine N-oxide (6) were isolated from the fungus Xylaria nigripes (Kl.) Sacc. Their structures were elucidated by comprehensive spectroscopic analyses and high-resolution mass spectrometry as well as by comparison with the literature. The absolute configuration was determined by Density Functional Theory (DFT) calculation methods. In addition, all of the compounds were evaluated for bioactivity via a cytotoxicity assay, an acetylcholinesterase inhibition assay and a cholesterol ester transfer protein inhibition assay.
出版日期: 2017
卷号: 14, 期号:1, 页码:e1600173
DOI标识: 10.1002/cbdv.201600173
语种: 英语
收录类别: SCI
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/46042
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Yuxi Normal Univ, Coll Resource & Environm, Yuxi 653100, Peoples R China
2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Lanhei Rd 132, Kunming 650201, Peoples R China

Recommended Citation:
Hu, Dongbao,Li, Ming. Three New Ergot Alkaloids from the Fruiting Bodies of Xylaria nigripes (Kl.) Sacc.[J]. CHEMISTRY & BIODIVERSITY,2017,14(1):e1600173.
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