Three New Ergot Alkaloids from the Fruiting Bodies of Xylaria nigripes (Kl.) Sacc. | |
Hu, Dongbao1,2; Li, Ming1 | |
2017 | |
发表期刊 | CHEMISTRY & BIODIVERSITY |
卷号 | 14期号:1页码:e1600173 |
摘要 | Three new ergot alkaloids, xylanigripones A - C (1-3) together with three known compounds, agroclavine (4), 8,9-didehydro-10-hydroxy-6,8-dimethylergolin (5), and (6S)-agroclavine N-oxide (6) were isolated from the fungus Xylaria nigripes (Kl.) Sacc. Their structures were elucidated by comprehensive spectroscopic analyses and high-resolution mass spectrometry as well as by comparison with the literature. The absolute configuration was determined by Density Functional Theory (DFT) calculation methods. In addition, all of the compounds were evaluated for bioactivity via a cytotoxicity assay, an acetylcholinesterase inhibition assay and a cholesterol ester transfer protein inhibition assay. |
关键词 | Xylaria Nigripes Ergot Alkaloids Dft Cetp Inhibitory Activity |
DOI | 10.1002/cbdv.201600173 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000394421900010 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/46042 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Yuxi Normal Univ, Coll Resource & Environm, Yuxi 653100, Peoples R China 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Lanhei Rd 132, Kunming 650201, Peoples R China |
推荐引用方式 GB/T 7714 | Hu, Dongbao,Li, Ming. Three New Ergot Alkaloids from the Fruiting Bodies of Xylaria nigripes (Kl.) Sacc.[J]. CHEMISTRY & BIODIVERSITY,2017,14(1):e1600173. |
APA | Hu, Dongbao,&Li, Ming.(2017).Three New Ergot Alkaloids from the Fruiting Bodies of Xylaria nigripes (Kl.) Sacc..CHEMISTRY & BIODIVERSITY,14(1),e1600173. |
MLA | Hu, Dongbao,et al."Three New Ergot Alkaloids from the Fruiting Bodies of Xylaria nigripes (Kl.) Sacc.".CHEMISTRY & BIODIVERSITY 14.1(2017):e1600173. |
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