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Metabolomics reveals the role of PPAR alpha in Tripterygium Wilfordii-induced liver injury 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 289, 页码: 16
Authors:  Dai, Manyun;  Peng, Wan;  Zhang, Ting;  Zhao, Qi;  Ma, Xiaofang;  Cheng, Yan;  Wang, Chunyan;  Li, Fei
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Tripterygium wilfordii  Liver injury  PPAR alpha  IL6-STAT3  Metabolomics  
Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 3, 页码: 588-601
Authors:  Li,Xu-xia;  Zhang,Peng;  Yang,Yang;  Wang,Jing-jing;  Zheng,Yan-jun;  Tan,Ji-liang;  Liu,Shen-yan;  Yan,Yong-ming;  Zhang,You-yi;  Cheng,Yong-xian;  Yang,Huang-tian
Favorite  |  View/Download:9/0  |  Submit date:2022/04/02
cardiac hypertrophy  pyrazine derivative  QF84139  phenylephrine  transverse aortic constriction  AMPK signaling pathway  PROTEIN-KINASE  MAMMALIAN TARGET  OVERLOAD  METFORMIN  MACROPHAGES  MECHANISMS  MEDICINE  ALPHA  CELLS  MODEL  
PXR mediates mifepristone-induced hepatomegaly in mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 146-156
Authors:  Yao,Xin-peng;  Jiao,Ting-ying;  Jiang,Yi-ming;  Fan,Shi-cheng;  Zhao,Ying-yuan;  Yang,Xiao;  Gao,Yue;  Li,Fei;  Zhou,Yan-ying;  Chen,Pan-pan;  Huang,Min;  Bi,Hui-chang
Favorite  |  View/Download:13/0  |  Submit date:2022/04/02
mifepristone  hepatomegaly  pregnane X receptor (PXR)  yes-associated protein (YAP)  
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models 期刊论文
CELL RESEARCH, 2021, 卷号: 31, 期号: 1, 页码: 17-24
Authors:  Wang,Gan;  Yang,Meng-Li;  Duan,Zi-Lei;  Liu,Feng-Liang;  Jin,Lin;  Long,Cheng-Bo;  Zhang,Min;  Tang,Xiao-Peng;  Xu,Ling;  Li,Ying-Chang;  Kamau,Peter Muiruri;  Yang,Lian;  Liu,Hong-Qi;  Xu,Jing-Wen;  Chen,Jie-Kai;  Zheng,Yong-Tang;  Peng,Xiao-Zhong;  Lai,Ren
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SARS  ENTRY  MERS  
High-quality evergreen azalea genome reveals tandem duplication-facilitated low-altitude adaptability and floral scent evolution 期刊论文
PLANT BIOTECHNOLOGY JOURNAL, 2021, 卷号: 19, 期号: 12, 页码: 2544-2560
Authors:  Wang,Xiuyun;  Gao,Yuan;  Wu,Xiaopei;  Wen,Xiaohui;  Li,Danqing;  Zhou,Hong;  Li,Zheng;  Liu,Bing;  Wei,Jianfen;  Chen,Fei;  Chen,Feng;  Zhang,Chengjun;  Zhang,Liangsheng;  Xia,Yiping
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Azalea  Rhododendron ovatum  altitude  adaptability  floral scent  terpene synthase (TPS)  tandem duplication  defence response  PHYLOGENETIC ANALYSIS  TERPENE SYNTHASES  PLANT VOLATILES  SALICYLIC-ACID  JASMONIC ACID  WHOLE-GENOME  GENE  DIVERSITY  TOOL  TRANSCRIPTOME  
Genome-Wide Analysis of the TCP Transcription Factor Genes in Dendrobium catenatum Lindl. 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 19, 页码: 10269
Authors:  Zhang,Li;  Li,Cheng;  Yang,Danni;  Wang,Yuhua;  Yang,Yongping;  Sun,Xudong
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Dendrobium catenatum Lindl.& nbsp  TCP transcription factor family & nbsp  phylogenetic analysis & nbsp  expression profiles & nbsp  phytohormone response  EXPRESSION ANALYSIS  JASMONIC ACID  DOMAIN  IDENTIFICATION  BIOSYNTHESIS  BRANCHED1  EVOLUTION  SEQUENCE  ELEMENTS  BINDING  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
Favorite  |  View/Download:20/0  |  Submit date:2022/04/02
Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Bulked segregant analysis reveals candidate genes responsible for dwarf formation in woody oilseed crop castor bean 期刊论文
SCIENTIFIC REPORTS, 2021, 卷号: 11, 期号: 1, 页码: 6277
Authors:  Wang,Zaiqing;  Yu,Anmin;  Li,Fei;  Xu,Wei;  Han,Bing;  Cheng,Xiaomao;  Liu,Aizhong
Favorite  |  View/Download:8/0  |  Submit date:2022/04/02
AUXIN TRANSPORT  CELL-WALL  ENDOPLASMIC-RETICULUM  PLANT HEIGHT  ARABIDOPSIS  HOMEOSTASIS  PROTEIN  BIOSYNTHESIS  ENCODES  SYSTEM  
HRESIMS-guided isolation of aspidosperma-scandine type bisindole alkaloids from Melodinus cochinchinensis and their anti-inflammatory and cytotoxic activities 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 184, 页码: 112673
Authors:  Li,Fang-Ru;  Liu,Lu;  Liu,Ya-Ping;  Wang,Jin-Tang;  Yang,Mei-Lian;  Khan,Afsar;  Qin,Xu-Jie;  Wang,Yu-Dan;  Cheng,Gui-Guang
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Melodinus cochinchinensis (Lour.) Merr. (Apocynaceae)  melokhanines  Bisindole alkaloids  Anti-inflammatory  Cytotoxicity  MONOTERPENOID INDOLE ALKALOIDS  CHEMISTRY  FRUITS  
New Genes Interacted With Recent Whole-Genome Duplicates in the Fast Stem Growth of Bamboos 期刊论文
MOLECULAR BIOLOGY AND EVOLUTION, 2021, 卷号: 38, 期号: 12, 页码: 5752-5768
Authors:  Jin,Guihua;  Ma,Peng-Fei;  Wu,Xiaopei;  Gu,Lianfeng;  Long,Manyuan;  Zhang,Chengjun;  Li,De-Zhu
Favorite  |  View/Download:14/0  |  Submit date:2022/04/02
fast stem growth  orphan genes  de novo genes  WGD  woody bamboos  evolutionary innovation  EVOLUTIONARY ORIGIN  DROSOPHILA-MELANOGASTER  PHYLOGENETIC ANALYSIS  VERTEBRATE EVOLUTION  RAPID EVOLUTION  HUMAN TISSUE  YOUNG GENES  TRANSCRIPTION  EXPRESSION  HOURGLASS