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YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
Authors:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
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Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity 期刊论文
BMC Cancer, 2019, 卷号: 19, 期号: 1
Authors:  Wang,Ning;  Fan,Yanhua;  Yuan,Chun-Mao;  Song,Jialei;  Yao,Yao;  Liu,Wuling;  Gajendran,Babu;  Zacksenhaus,Eldad;  Li,Yanmei;  Liu,Jielin;  Hao,Xiao Jiang;  Ben-David,Yaacov
Favorite  |  View/Download:21/0  |  Submit date:2019/08/13
Cancer  Leukemia  Chinese medicinal plant  Melia azedarach  Drug screen  ERK1/2 agonists  Differentiation  Apoptosis  
microRNA-375 inhibits colorectal cancer cells proliferation by downregulating JAK2/STAT3 and MAP3K8/ERK signaling pathways 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 10, 页码: 16633-16641
Authors:  Wei, Ran;  Yang, Qin;  Han, Bing;  Li, Yan;  Yao, Kun;  Yang, Xiuyu;  Chen, Zexi;  Yang, Shanshan;  Zhou, Jiaqi;  Li, Meizhang;  Yu, Haijing;  Yu, Min;  Cui, Qinghua
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Microrna-375  Colorectal Cancer  Jak2/stat3 Pathway  Map3k8/erk Pathway  Atg7  
Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 40, 页码: 42704-42716
Authors:  Luo, Xiangjian;  Yang, Lifang;  Xiao, Lanbo;  Xia, Xiaofeng;  Dong, Xin;  Zhong, Juanfang;  Liu, Ying;  Li, Namei;  Chen, Ling;  Li, Hongde;  Li, Wei;  Liu, Wenbin;  Yu, Xinfang;  Chen, Hanyong;  Tang, Min;  Weng, Xinxian;  Yi, Wei;  Bode, Ann;  Dong, Zigang;  Liu, Jikai;  Cao, Ya
View  |  Adobe PDF(5262Kb)  |  Favorite  |  View/Download:114/4  |  Submit date:2016/06/27
Grifolin  Erk1/2  Dnmt1  Metastasis  
Cyclopeptide RA-V inhibits angiogenesis by down-regulating ERK1/2 phosphorylation in HUVEC and HMEC-1 endothelial cells 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2011, 卷号: 164, 期号: 7, 页码: 1883-1898
Authors:  Yue, Grace G. L.;  Fan, Jun-Ting;  Lee, Julia K. M.;  Zeng, Guang-Zhi;  Ho, Tina W. F.;  Fung, Kwok-Pui;  Leung, Ping-Chung;  Tan, Ning-Hua;  Lau, Clara B. S.
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Cyclopeptide  Ra-v  Angiogenesis  Erk1  2  Rubia Yunnanensis  Huvec  Hmec-1  Endothelial Cells  
DAPK1 mediates the G1 phase arrest in human nasopharyngeal carcinoma cells induced by grifolin, a potential antitumor natural product 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2011, 卷号: 670, 期号: 2-3, 页码: 427-434
Authors:  Luo, Xiang-jian;  Li, Wei;  Yang, Li-fang;  Yu, Xin-fang;  Xiao, Lan-bo;  Tang, Min;  Dong, Xin;  Deng, Qi-pan;  Bode, Ann M.;  Liu, Ji-kai;  Cao, Ya
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Grifolin  Dapk1  Cell Cycle  P21  Erk1/2  Npc  Mushroom  
Grifolin, a potential antitumor natural product from the mushroom Albatrellus confluens, induces cell-cycle arrest in G1 phase via the ERK1/2 pathway 期刊论文
CANCER LETTERS, 2007, 卷号: 258, 期号: 2, 页码: 199-207
Authors:  Ye, Mao;  Luo, Xiangjian;  Li, Lili;  Shi, Ying;  Tan, Ming;  Weng, Xinxian;  Li, Wei;  Liu, Jikai;  Cao, Ya
Adobe PDF(570Kb)  |  Favorite  |  View/Download:300/98  |  Submit date:2011/12/19
Grifolin  Cell Cycle  Erk1/2  Erk5