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ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:  Zhou,Gui-Feng;  Tang,Jing;  Ma,Yuan-Lin;  Fu,Xian;  Liu,Jun-Yan;  Yang,Ren-Zhi;  Zhang,Hong-Sheng;  Cai,Xiang-Hai;  Wang,Jing-Wen;  Xie,Xiao-Yong;  Song,Li;  Luo,Biao;  Chen,Jian;  Chen,Long;  Deng,Xiao-Juan;  Chen,Guo-Jun
浏览  |  Adobe PDF(6685Kb)  |  收藏  |  浏览/下载：70/13  |  提交时间：2024/05/09
conophylline  ARL6IP1  5'UTR  FXR1  BACE1 translation  AMYLOID PRECURSOR PROTEIN  A-BETA  TRANSGENIC MICE  MOUSE MODEL  NEURODEGENERATION  EXPRESSION  REDUCTION  MEMBRANE  MEMORY  ER  
Recent Studies on Protective Effects of Walnuts against Neuroinflammation 期刊论文
NUTRIENTS, 2022, 卷号: 14, 期号: 20, 页码: 4360
作者:  Tan, Bing;  Wang, Yuxi;  Zhang, Xudong;  Sun, Xiangjun
浏览  |  Adobe PDF(999Kb)  |  收藏  |  浏览/下载：102/12  |  提交时间：2024/04/30
walnuts  neuroinflammation  neurodegenerative diseases  oxidative stress  antioxidant activity  gut microbes  ALPHA-LINOLENIC ACID  BETA-AMYLOID PROTEIN  NF-KAPPA-B  OXIDATIVE STRESS  COGNITIVE IMPAIRMENT  MEDITERRANEAN DIET  INDUCED ACTIVATION  BV-2 MICROGLIA  ELLAGIC ACID  GALLIC ACID  
Multifunctional Anti-Alzheimer's Disease Effects of Natural Xanthone Derivatives: A Primary Structure-Activity Evaluation 期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10, 页码: 842208
作者:  Hu, Xiaoyu;  Liu, Chan;  Wang, Kaichun;  Zhao, Lanxue;  Qiu, Yu;  Chen, Hongzhuan;  Hu, Jiangmiao;  Xu, Jianrong
浏览  |  Adobe PDF(2230Kb)  |  收藏  |  浏览/下载：13/2  |  提交时间：2024/08/21
alpha-mangostin  Alzheimer's disease  multifunctional  structure-activity  neuroinflammation  amyloid beta  BETA-AMYLOID PEPTIDES  BLOOD-BRAIN-BARRIER  CENTRAL-NERVOUS-SYSTEM  ALPHA-MANGOSTIN  MICROGLIA  OLIGOMERS  AGGREGATION  MODULATION  PRODUCTS  DESIGN  
Unprecedented polycyclic polyprenylated acylphloroglucinols with anti-Alzheimer's activity from St. John's wort 期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 12, 期号: 34, 页码: 11438-11446
作者:  Guo,Yi;  Huang,Fang;  Sun,Weiguang;  Zhou,Yuan;  Chen,Chunmei;  Qi,Changxing;  Yang,Jing;  Li,Xiao-Nian;  Luo,Zengwei;  Zhu,Hucheng;  Wang,Xiaochuan;  Zhang,Yonghui
收藏  |  浏览/下载：140/0  |  提交时间：2022/04/02
AMYLOID-BETA  NEUROFIBRILLARY DEGENERATION  HYPERFORIN  NEUROTOXICITY  PATHOGENESIS  INHIBITION  BACE1  DRUG  TAU  
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 2, 页码: 262-267
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
收藏  |  浏览/下载：83/0  |  提交时间：2022/04/02
AMYLOID PRECURSOR PROTEIN  INSULIN-DEGRADING ENZYME  BETA-PROTEIN  GEMFIBROZIL  PREVENTION  SECRETASE  ADAM10  MEN  
Pu-Erh Tea Extract Induces the Degradation of FET Family Proteins Involved in the Pathogenesis of Amyotrophic Lateral Sclerosis 期刊论文
BIOMED RESEARCH INTERNATIONAL, 2014, 页码: 254680
作者:  Yu, Yang;  Hayashi, Shuhei;  Cai, Xianbin;  Fang, Chongye;  Shi, Wei;  Tsutsui, Hiroko;  Sheng, Jun;  Hayashi,SH (reprint author),Hyogo Coll Med,Dept Pu Erh Tea & Med Sci,1-1 Mukogawa Cho,Nishinomiya,Hyogo 6638501,Japan.;  zoup1130@hyo-med.ac.jp;  shengj@ynau.edu.cn
浏览  |  Adobe PDF(5682Kb)  |  收藏  |  浏览/下载：337/50  |  提交时间：2014/06/23
Wild-type Fus  Stress Granules  Alpha-synuclein  Amyloid-beta  Mutations  Tdp-43  Toxicity  Fibrils  Gene  Fermentation  
Gastrodia elata modulates amyloid precursor protein cleavage and cognitive functions in mice 期刊论文
BIOSCIENCE TRENDS, 2011, 卷号: 5, 期号: 3, 页码: 129-138
作者:  Mishra, Manisha;  Huang, Junjie;  Lee, Yin Yeng;  Chua, Doreen See Kin;  Lin, Xiaoyan;  Hu, Jiang-Miao;  Heese, Klaus
浏览  |  Adobe PDF(389Kb)  |  收藏  |  浏览/下载：178/59  |  提交时间：2015/08/17
Alzheimer's Disease  Beta-amyloid Precursor Protein  Kampo  Neurodegeneration  Traditional Chinese Medicine  
Estrogenic and Neuroprotective Properties of Scutellarin from Erigeron breviscapus: A Drug against Postmenopausal Symptoms and Alzheimer's Disease 期刊论文
PLANTA MEDICA, 2009, 卷号: 75, 期号: 14, 页码: 1489-1493
作者:  Zhu, Judy T. T.;  Choi, Roy C. Y.;  Li, Jun;  Xie, Heidi Q. H.;  Bi, Cathy W. C.;  Cheung, Anna W. H.;  Dong, Tina T. X.;  Jiang, Zhi Y.;  Chen, Ji J.;  Tsim, Karl W. K.
浏览  |  Adobe PDF(181Kb)  |  收藏  |  浏览/下载：176/69  |  提交时间：2015/08/17
Beta-amyloid  Scutellarin  Erigeron Breviscapus  Compositae  Estrogen  Neuroprotection