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New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit beta-Amyloid42 Production and Phospho-Tau (Thr217) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1487
作者:  Li,Sheng;  Han,Ling-Ling;  Huang,Ke-Pu;  Ma,Ye-Han;  Guo,Ling-Li;  Guo,Yarong;  Ran,Xiaoqian;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rongcan;  Zhang,Yu
Adobe PDF(5266Kb)  |  收藏  |  浏览/下载：0/0  |  提交时间：2024/05/09
Tabernaemontana crassa  monoterpenoid indole alkaloids  A beta 42  phospho-tau (Thr217)  Alzheimer's disease  ALZHEIMERS-DISEASE  BISINDOLE ALKALOIDS  CDK5  GEMFIBROZIL  PREVENTION  ALGORITHM  AUTOPHAGY  MODELS  PLANTS  MOUSE  
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
Adobe PDF(2579Kb)  |  收藏  |  浏览/下载：135/49  |  提交时间：2023/09/08
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 2, 页码: 262-267
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
收藏  |  浏览/下载：56/0  |  提交时间：2022/04/02
AMYLOID PRECURSOR PROTEIN  INSULIN-DEGRADING ENZYME  BETA-PROTEIN  GEMFIBROZIL  PREVENTION  SECRETASE  ADAM10  MEN  
Synthesis and PDE-10 Inhibition of 3-substituted Phenylimino-indolin-2-ones 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 卷号: 126, 页码: 34-34
作者:  Wu, Ya;  Lin, Zhiwei;  Bai, Yun;  Zhang, Yu;  Cai, Qing;  Mu, Shuzhen;  Han, Weiwei;  Hao, Xiaojiang;  Chen, Gang
收藏  |  浏览/下载：164/0  |  提交时间：2020/03/24
Autocatalytic synthesis of 3-ethyl-3-hydroxy-indole-2-ones and their neuroprotection and antitumor activities' evaluation 期刊论文
COMPTES RENDUS CHIMIE, 2018, 卷号: 21, 期号: 5, 页码: 471-474
作者:  Chen, Gang;  Lin, Jiao;  Zhang, Jie;  Wu, Ya;  Gu, Xuefan;  Hao, Xiaojiang;  Zhang, Yu
收藏  |  浏览/下载：110/0  |  提交时间：2019/03/29
Isatin  3-Ethyl-3-hydroxy-indole-2-one  Antitumor  Neuroprotection  
Synthesis, Neuro-protection and Anti-cancer Activities of Simple Isatin Mannich and Schiff Bases 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2016, 卷号: 13, 期号: 5, 页码: 395-400
作者:  Chen, Gang;  Ning, Yang;  Zhao, Wei;  Zhang, Yanqiu;  Zhang, Yu;  Hao, Xiaojiang;  Wang, Ye;  Mu, Shuzhen
Adobe PDF(1361Kb)  |  收藏  |  浏览/下载：217/69  |  提交时间：2016/08/22
Isatin  Mannich Base  Schiff Base  Synthesis  Neuro-protection  Anti-tumor  
Theoretical study of regioselectivity in the synthesis of spiro [pyrrolidine-2,3'-oxindole] compounds by [3+2] cycloaddition 期刊论文
RESEARCH ON CHEMICAL INTERMEDIATES, 2015, 卷号: 41, 期号: 7, 页码: 4987-4996
作者:  Chen, Gang;  Yang, Jing;  Gao, Suo;  Zhang, Yu;  Hao, Xiaojiang
Adobe PDF(1404Kb)  |  收藏  |  浏览/下载：144/37  |  提交时间：2015/12/17
Regioselectivity  Theoretical  Spiro-oxindole  [3+2] Cycloaddition  
Synthesis, Cytoprotective and Anti-tumor Activities of Isatin Schiff Bases 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2015, 卷号: 12, 期号: 10, 页码: 802-805
作者:  Chen, Gang;  Meng, Mei;  Zhang, Yu;  Hao, Xiaojiang;  Wang, Ye;  Mu, Shuzhen
Adobe PDF(1108Kb)  |  收藏  |  浏览/下载：137/38  |  提交时间：2016/01/19
Isatin  Synthesis  Schiff Base  Structure  Cytoprotective  Anti-tumor  
Peganumine A, a beta-Carboline Dimer with a New Octacyclic Scaffold from Peganum harmala 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 15, 页码: 4028-4031
作者:  Wang, Kai-Bo;  Di, Ying-Tong;  Bao, Yu;  Yuan, Chun-Mao;  Chen, Gang;  Li, Da-Hong;  Bai, Jiao;  He, Hong-Ping;  Hao, Xiao-Jiang;  Pei, Yue-Hu;  Jing, Yong-Kui;  Li, Zhan-Lin;  Hua, Hui-Ming;  Li, ZL (reprint author), Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Liaoning, Peoples R China.;  lzl1030@hotmail.com;  huimhua@163.com
Adobe PDF(295Kb)  |  收藏  |  浏览/下载：302/89  |  提交时间：2014/10/11
Light-emitting-diodes  Alkaloid Extract  Potent  L.  Derivatives  Efficiency  Toxicity  Harmine  Cascade  Growth  
Synthesis and evaluation of isatin derivatives as corrosion inhibitors for Q235A steel in highly concentrated HCl 期刊论文
RESEARCH ON CHEMICAL INTERMEDIATES, 2013, 卷号: 39, 期号: 8, 页码: 3669-3678
作者:  Chen, Gang;  Su, Hui-jun;  Song, Ying-pan;  Gao, Yu;  Zhang, Jie;  Hao, Xiao-jiang;  Zhao, Jing-rui
Adobe PDF(459Kb)  |  收藏  |  浏览/下载：250/55  |  提交时间：2013/11/12
Isatin Derivatives  Q235a Steel  Anticorrosion  Formulation