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Natural products against hematological malignancies and identification of their targets 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2015, 卷号: 58, 期号: 12, 页码: 1191-1201
作者:  Xu Ying;  Liu JinBao;  Wu YingLi;  Guo QingLong;  Sun HanDong;  Chen GuoQiang
Adobe PDF(756Kb)  |  收藏  |  浏览/下载：176/29  |  提交时间：2016/05/04
Natural Products  Adenanthin  Hematological Malignancies  Target Identification  
Preventive and Therapeutic Effects of Adenanthin on Experimental Autoimmune Encephalomyelitis by Inhibiting NF-kappa B Signaling 期刊论文
JOURNAL OF IMMUNOLOGY, 2013, 卷号: 191, 期号: 5, 页码: 2115-2125
作者:  Yin, Qian-Qian;  Liu, Chuan-Xu;  Wu, Ying-Li;  Wu, Shao-Fang;  Wang, Yan;  Zhang, Xia;  Hu, Xiao-Juan;  Pu, Jian-Xin;  Lu, Ying;  Zhou, Hu-Chen;  Wang, Hong-Lin;  Nie, Hong;  Sun, Han-Dong;  Chen, Guo-Qiang
浏览  |  Adobe PDF(2420Kb)  |  收藏  |  浏览/下载：335/43  |  提交时间：2013/10/16
Autoreactive T-cells  Multiple-sclerosis  Rheumatoid-arthritis  Glatiramer Acetate  Activation  Inflammation  System  Roles  Mice  Differentiation  
Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells 期刊论文
NATURE CHEMICAL BIOLOGY, 2012, 卷号: 8, 期号: 5, 页码: 486-493
作者:  Liu, Chuan-Xu;  Yin, Qian-Qian;  Zhou, Hu-Chen;  Wu, Ying-Li;  Pu, Jian-Xin;  Xia, Li;  Liu, Wei;  Huang, Xin;  Jiang, Tao;  Wu, Ming-Xuan;  He, Li-Cai;  Zhao, Ya-Xue;  Wang, Xiao-Lin;  Xiao, Wei-Lie;  Chen, Hong-Zhuan;  Zhao, Qian;  Zhou, Ai-Wu;  Wang, Li-Shun;  Sun, Han-Dong;  Chen, Guo-Qiang
浏览  |  Adobe PDF(1434Kb)  |  收藏  |  浏览/下载：655/197  |  提交时间：2012/06/07
Cimicifuga Foetida  Cycloartane  Cytotoxicity  Ranunculaceae  Breast-cancer Cells  Crude Drug Shoma  Racemosa Extract  Simplex Wormsk  Cyclolanostanol Xylosides  Triterpene Glycosides  Chemical-constituents  Prostate-cancer  Aerial Parts  Black Cohosh  
19-Oxygenated ent-Kaurane Diterpenoids from Isodon pharicus 期刊论文
PLANTA MEDICA, 2012, 卷号: 78, 期号: 1, 页码: 52-58
作者:  Zhao, Yong;  Pu, Jian-Xin;  Huang, Sheng-Xiong;  Ding, Li-Sheng;  Li, Li-Mei;  Li, Xian;  Yang, Li-Bin;  Xiao, Wei-Lie;  Wu, Ying-Li;  Chen, Guo-Qiang;  Sun, Han-Dong
Adobe PDF(8091Kb)  |  收藏  |  浏览/下载：393/67  |  提交时间：2012/07/26
Lamiaceae  Isodon Pharicus  Diterpenoid  Cytotoxicity  
一种治疗急性早幼粒细胞白血病的药物靶标及其抑制剂 专利
专利类型: 发明, 专利号: CN201110305958.8, 申请日期: 2011-10-11, 公开日期: 2013-04-17
发明人:  陈国强;  孙汉董;  吴英理;  刘传绪;  阴倩倩;  普建新;  肖伟烈
Adobe PDF(2117Kb)  |  收藏  |  浏览/下载：178/7  |  提交时间：2016/12/19
Antiproliferative Diterpenoids from the Leaves of Isodon rubescens 期刊论文
PLANTA MEDICA, 2011, 卷号: 77, 期号: 2, 页码: 169-174
作者:  Gao, Xue-Mei;  Luo, Xiao;  Pu, Jian-Xin;  Wu, Ying-Li;  Zhao, Yong;  Yang, Li Bin;  He, Fei;  Li, Xiao Nian;  Xiao, Wei-Lie;  Chen, Guo-Qiang;  Sun, Han-Dong
Adobe PDF(11711Kb)  |  收藏  |  浏览/下载：282/47  |  提交时间：2012/07/18
Isodon Rubescens  Labiatae  Cytotoxicity  Diterpenoid  
Pharicin B stabilizes retinoic acid receptor-alpha and presents synergistic differentiation induction with ATRA in myeloid leukemic cells 期刊论文
BLOOD, 2010, 卷号: 116, 期号: 24, 页码: 5289-5297
作者:  Gu, Zhi-Min;  Wu, Ying-Li;  Zhou, Mei-Yi;  Liu, Chuan-Xu;  Xu, Han-Zhang;  Yan, Hua;  Zhao, Yong;  Huang, Ying;  Sun, Han-Dong;  Chen, Guo-Qiang
Adobe PDF(963Kb)  |  收藏  |  浏览/下载：120/35  |  提交时间：2015/08/17
腺花素在制药中的应用 专利
专利类型: 发明, 专利号: CN201010542854.4, 申请日期: 2010-11-15, 公开日期: 2012-05-23
发明人:  陈国强;  孙汉董;  吴英理;  刘传绪;  阴倩倩;  普建新;  肖伟烈
Adobe PDF(3052Kb)  |  收藏  |  浏览/下载：123/5  |  提交时间：2016/12/19
Pharicin A, a novel natural ent-kaurene diterpenoid, induces mitotic arrest and mitotic catastrophe of cancer cells by interfering with BubR1 function 期刊论文
CELL CYCLE, 2010, 卷号: 9, 期号: 14, 页码: 2897-2907
作者:  Xu, Han-Zhang;  Huang, Ying;  Wu, Ying-Li;  Zhao, Yong;  Xiao, Wei-Lie;  Lin, Qi-Shan;  Sun, Han-Dong;  Dai, Wei;  Chen, Guo-Qiang
浏览  |  Adobe PDF(3997Kb)  |  收藏  |  浏览/下载：122/35  |  提交时间：2015/08/17
Pharicin a  Mitotic Arrest  Leukemia  Tumor Cells  Spindle Checkpoint  
Four New Nortriterpenoids from Schisandra lancifolia 期刊论文
HELVETICA CHIMICA ACTA, 2010, 卷号: 93, 期号: 10, 页码: 1975-1982
作者:  Xiao, Wei-Lie;  Wu, Ying-Li;  Shang, Shan-Zhai;  He, Fei;  Luo, Xiao;  Yang, Guang-Yu;  Pu, Jian-Xin;  Chen, Guo-Qiang;  Sun, Han-Dong
Adobe PDF(252Kb)  |  收藏  |  浏览/下载：283/80  |  提交时间：2012/03/21
Saponins  Cochinchinensis