| Antiproliferative Diterpenoids from the Leaves of Isodon rubescens | |
Gao, Xue-Mei1,4; Luo, Xiao1; Pu, Jian-Xin1 ; Wu, Ying-Li2,3; Zhao, Yong1; Yang, Li Bin1; He, Fei1; Li, Xiao Nian1; Xiao, Wei-Lie1; Chen, Guo-Qiang2,3; Sun, Han-Dong1
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| Corresponding Author | Sun, HD (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Lan Hei Rd, Kunming 650204, Yunnan, Peoples R China |
| 2011 | |
| Source Publication | PLANTA MEDICA
 |
| ISSN | 0032-0943 |
| Volume | 77Issue:2Pages:169-174 |
| Abstract | A phytochemical study of Isodon rubescens leaves led to the isolation of five new diterpenoids, isorubesins A-E (1 - 5), and fifteen known diterpenoids. The structures of these new compounds were elucidated by spectroscopic evidence. Most of the diterpenoids were tested for cytotoxicity against NB4, A549, SHSY5Y, PC3, and MCF7 human tumor cells. Some of them showed potent inhibitory activity. Compound 5 is the first reported atisane-type diterpenoid from this plant. |
| Keyword | Isodon Rubescens Labiatae Cytotoxicity Diterpenoid |
| Subject Area | Plant Sciences ; Pharmacology & Pharmacy |
| DOI | 10.1055/s-0030-1250165 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000286461000012 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/13575 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Shanghai Jiao Tong Univ, Sch Med, Dept Pathophysiol, Shanghai 200030, Peoples R China 3.Shanghai Jiao Tong Univ, Sch Med, Key Lab Cell Differentiat & Apoptosis, Chinese Minist Educ, Shanghai 200030, Peoples R China 4.Yunnan Nationalities Univ, Sch Chem & Biotechnol, Kunming 650031, Peoples R China |
| Recommended Citation GB/T 7714 | Gao, Xue-Mei,Luo, Xiao,Pu, Jian-Xin,et al. Antiproliferative Diterpenoids from the Leaves of Isodon rubescens[J]. PLANTA MEDICA,2011,77(2):169-174. |
| APA | Gao, Xue-Mei.,Luo, Xiao.,Pu, Jian-Xin.,Wu, Ying-Li.,Zhao, Yong.,...&Sun, Han-Dong.(2011).Antiproliferative Diterpenoids from the Leaves of Isodon rubescens.PLANTA MEDICA,77(2),169-174. |
| MLA | Gao, Xue-Mei,et al."Antiproliferative Diterpenoids from the Leaves of Isodon rubescens".PLANTA MEDICA 77.2(2011):169-174. |
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