Antiproliferative Diterpenoids from the Leaves of Isodon rubescens

doi:10.1055/s-0030-1250165

	Antiproliferative Diterpenoids from the Leaves of Isodon rubescens
	Gao, Xue-Mei 1,4; Luo, Xiao 1; Pu, Jian-Xin1 ; Wu, Ying-Li 2,3; Zhao, Yong 1; Yang, Li Bin 1; He, Fei 1; Li, Xiao Nian 1; Xiao, Wei-Lie 1; Chen, Guo-Qiang 2,3; Sun, Han-Dong1
通讯作者	Sun, HD (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Lan Hei Rd, Kunming 650204, Yunnan, Peoples R China
	2011
发表期刊	PLANTA MEDICA
ISSN	0032-0943
卷号	77 期号:2 页码:169-174
摘要	A phytochemical study of Isodon rubescens leaves led to the isolation of five new diterpenoids, isorubesins A-E (1 - 5), and fifteen known diterpenoids. The structures of these new compounds were elucidated by spectroscopic evidence. Most of the diterpenoids were tested for cytotoxicity against NB4, A549, SHSY5Y, PC3, and MCF7 human tumor cells. Some of them showed potent inhibitory activity. Compound 5 is the first reported atisane-type diterpenoid from this plant.
关键词	Isodon Rubescens Labiatae Cytotoxicity Diterpenoid
学科领域	Plant Sciences ; Pharmacology & Pharmacy
DOI	10.1055/s-0030-1250165
收录类别	SCI
语种	英语
WOS记录号	WOS:000286461000012
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/13575
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Shanghai Jiao Tong Univ, Sch Med, Dept Pathophysiol, Shanghai 200030, Peoples R China 3.Shanghai Jiao Tong Univ, Sch Med, Key Lab Cell Differentiat & Apoptosis, Chinese Minist Educ, Shanghai 200030, Peoples R China 4.Yunnan Nationalities Univ, Sch Chem & Biotechnol, Kunming 650031, Peoples R China
推荐引用方式 GB/T 7714	Gao, Xue-Mei,Luo, Xiao,Pu, Jian-Xin,et al. Antiproliferative Diterpenoids from the Leaves of Isodon rubescens[J]. PLANTA MEDICA,2011,77(2):169-174.
APA	Gao, Xue-Mei.,Luo, Xiao.,Pu, Jian-Xin.,Wu, Ying-Li.,Zhao, Yong.,...&Sun, Han-Dong.(2011).Antiproliferative Diterpenoids from the Leaves of Isodon rubescens.PLANTA MEDICA,77(2),169-174.
MLA	Gao, Xue-Mei,et al."Antiproliferative Diterpenoids from the Leaves of Isodon rubescens".PLANTA MEDICA 77.2(2011):169-174.

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