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题名: Antiproliferative Diterpenoids from the Leaves of Isodon rubescens
作者: Gao, Xue-Mei1, 4; Luo, Xiao1; Pu, Jian-Xin1; Wu, Ying-Li2, 3; Zhao, Yong1; Yang, Li Bin1; He, Fei1; Li, Xiao Nian1; Xiao, Wei-Lie1; Chen, Guo-Qiang2, 3; null(孙汉董)1
刊名: PLANTA MEDICA
关键词: Isodon rubescens ; Labiatae ; cytotoxicity ; diterpenoid
英文摘要: A phytochemical study of Isodon rubescens leaves led to the isolation of five new diterpenoids, isorubesins A-E (1 - 5), and fifteen known diterpenoids. The structures of these new compounds were elucidated by spectroscopic evidence. Most of the diterpenoids were tested for cytotoxicity against NB4, A549, SHSY5Y, PC3, and MCF7 human tumor cells. Some of them showed potent inhibitory activity. Compound 5 is the first reported atisane-type diterpenoid from this plant.
出版日期: 2011
卷号: 77, 期号:2, 页码:169-174
DOI标识: 10.1055/s-0030-1250165
语种: 英语
ISSN号: 0032-0943
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/13575
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
2.Shanghai Jiao Tong Univ, Sch Med, Dept Pathophysiol, Shanghai 200030, Peoples R China
3.Shanghai Jiao Tong Univ, Sch Med, Key Lab Cell Differentiat & Apoptosis, Chinese Minist Educ, Shanghai 200030, Peoples R China
4.Yunnan Nationalities Univ, Sch Chem & Biotechnol, Kunming 650031, Peoples R China

Recommended Citation:
Gao, XM; Luo, XA; Pu, JX; Wu, YL; Zhao, Y; Yang, LB; He, F; Li, XN; Xiao, WL; Chen, GQ; Sun, HD.Antiproliferative Diterpenoids from the Leaves of Isodon rubescens,PLANTA MEDICA,2011,77(2):169-174
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