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Synthesis and biological evaluation of novel 3-benzylcoumarin-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 4, 页码: 6
作者:  Wang, Xue-Quan;  Chen, Xue-Bing;  Ye, Ping-Ting;  Yang, Zhi-Xin;  Bai, Meng-Jiao;  Duan, Su-Yue;  Li, Yan;  Yang, Xiao-Dong
收藏  |  浏览/下载:165/0  |  提交时间:2020/03/18
3-Benzylcoumarin  Imidazolium salts  Biological evaluation  Cytotoxic activity  Structure-activity relationships  
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载:151/0  |  提交时间:2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Synthesis and biological activity of new bisbenzofuran-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020
作者:  Wang, Xue-Quan;  Ye, Ping-Ting;  Bai, Meng-Jiao;  Miu, Wei-Hang;  Yang, Zhi-Xin;  Duan, Su-Yue;  Li, Tian-Tian;  Li, Yan;  Yang, Xiao-Dong
浏览  |  Adobe PDF(2161Kb)  |  收藏  |  浏览/下载:122/23  |  提交时间:2021/01/05
Synthesis and biological evaluation of chepraecoxin A derivatives as alpha-glucosidase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020
作者:  Yang, Xiao-Tong;  Geng, Chang-An;  Li, Tian-Ze;  Deng, Zhen-Tao;  Chen, Ji-Jun
浏览  |  Adobe PDF(675Kb)  |  收藏  |  浏览/下载:142/27  |  提交时间:2021/01/05
Hypolipidemic constituents from the aerial portion of Sibiraea angustata 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020
作者:  Liu, Hongdong;  Zhang, Ting;  Jiang, Piao;  Zhu, Weifeng;  Yu, Songhua;  Liu, Yong;  Li, Bin;  Li, Fei
浏览  |  Adobe PDF(1300Kb)  |  收藏  |  浏览/下载:107/35  |  提交时间:2021/01/05
A Novel bis-indole Alkaloid from the Flowers of Rauvolfia yunnanensis Tsiang and its Antihypertension Activity 期刊论文
LETTERS IN ORGANIC CHEMISTRY, 2020, 卷号: 17, 期号: 2, 页码: 96-100
作者:  Wang, Haibo;  Liu, Xikui
收藏  |  浏览/下载:72/0  |  提交时间:2020/03/18
Alkaloid  Bis-indole alkaloid  Rauvolfia yunnanensis  rauvolfia flowers  antihypertension  reserpine  
Glucosides from the Fresh Flowers of Juglans regia L. and Their Biological Evaluation 期刊论文
LETTERS IN ORGANIC CHEMISTRY, 2020, 卷号: 17, 期号: 1, 页码: 31-35
作者:  Wang, Haibo;  Liu, Xikui
收藏  |  浏览/下载:114/0  |  提交时间:2020/03/18
alpha-Tetralonyl glucosides  Juglans regia  juglandaceae  antioxidant  DPPH  antibacterial  
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
作者:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Ma, Rui-Jing;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao
Adobe PDF(500Kb)  |  收藏  |  浏览/下载:404/183  |  提交时间:2019/03/18
Biodnylated Camptothecin Derivatives  Anticancer Activity  Synthesis  Click Chemistry  Structure-activity Relationships (Sars)  
Synthesis and anti-proliferative activity of allogibberic acid derivatives containing 1,2,3-triazole pharmacophore 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 14, 页码: 2543-2549
作者:  Wu, Ming-Jiang;  Wu, Dong-Mei;  Chen, Jing-Bo;  Zhao, Jing-Feng;  Gong, Liang;  Gong, Ya-Xiao;  Li, Yan;  Yang, Xiao-Dong;  Zhang, Hongbin
收藏  |  浏览/下载:128/0  |  提交时间:2019/03/29
Isocostunolide inhibited glioma stem cell by suppression proliferation and inducing caspase dependent apoptosis 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 页码: 2863-2867
作者:  Dai, Zhi;  Li, Shi-Rong;  Zhu, Pei-Feng;  Liu, Lu;  Wang, Bei;  Liu, Ya-Ping;  Luo, Xiao-Dong;  Zhao, Xu-Dong
浏览  |  Adobe PDF(2209Kb)  |  收藏  |  浏览/下载:277/61  |  提交时间:2017/07/18
Isocostunolide  Glioma Stem Cells  Cell Proliferation  Apoptosis  Colony Formation