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A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
作者:  Chen,Yue-Gui;  Li,De-Sen;  Ling,Yi;  Liu,Yan-Chun;  Zuo,Zhi-Li;  Gan,Li-She;  Luo,Shi-Hong;  Hua,Juan;  Chen,Ding-Yuan;  Xu,Fan;  Li,Man;  Guo,Kai;  Liu,Yan;  Gershenzon,Jonathan;  Li,Sheng-Hong
Adobe PDF(2177Kb)  |  收藏  |  浏览/下载：106/54  |  提交时间：2022/04/02
enzyme engineering  immunosuppressive activity  Leucosceptrum canum  macrocyclic terpenoids  sesterterpene synthase  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  SCALE INSECT  SESTERTERPENOIDS  CONVERSION  EVOLUTION  PRECURSOR  HARBOR  
Bioinspired Network Analysis Enabled Divergent Syntheses and Structure Revision of Pentacyclic Cytochalasans 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 29, 页码: 15963-15971
作者:  Wu,Hai;  Ding,Yiming;  Hu,Kun;  Long,Xianwen;  Qu,Chunlei;  Puno,Pema-Tenzin;  Deng,Jun
Adobe PDF(2675Kb)  |  收藏  |  浏览/下载：68/17  |  提交时间：2022/04/02
bioinspired network analysis  biomimetic synthesis  natural products  pentacyclic cytochalasans  structure elucidation  DIELS-ALDER REACTION  ISOINDOLONE NUCLEUS  RING-SYSTEM  MEROCYTOCHALASANS  REASSIGNMENT  DESATURATION  GENERATION  ALKALOIDS  CARBONATE  SKELETONS  
Merging Reagent Modulation and Remote Anchimeric Assistance for Glycosylation: Highly Stereoselective Synthesis of alpha-Glycans up to a 30-mer 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 22, 页码: 12597-12606
作者:  Zhang,Yunqin;  He,Haiqing;  Chen,Zixi;  Huang,Yingying;  Xiang,Guisheng;  Li,Penghua;  Yang,Xingkuan;  Lu,Gang;  Xiao,Guozhi
Adobe PDF(3663Kb)  |  收藏  |  浏览/下载：65/11  |  提交时间：2022/04/02
1  2-cis glycosylation  reagent modulation  remote anchimeric assistance  structure elucidation  synthetic methods  
(-)-Isoscopariusin A, a Naturally Occurring Immunosuppressive Meroditerpenoid: Structure Elucidation and Scalable Chemical Synthesis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 23, 页码: 12859-12867
作者:  Yan,Bing-Chao;  Zhou,Min;  Li,Jian;  Li,Xiao-Nian;  He,Shi-Jun;  Zuo,Jian-Ping;  Sun,Han-Dong;  Li,Ang;  Puno,Pema-Tenzin
Adobe PDF(1930Kb)  |  收藏  |  浏览/下载：66/13  |  提交时间：2022/04/02
bioactivity  cyclobutane  natural products  scalable synthesis  structure elucidation