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The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
Adobe PDF(4461Kb)  |  收藏  |  浏览/下载：221/67  |  提交时间：2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
作者:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(3915Kb)  |  收藏  |  浏览/下载：203/40  |  提交时间：2019/07/29
Sense Ginsenosides From Ginsengs: Structure-Activity Relationship in Autophagy 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2019, 卷号: 14, 期号: 6, 页码: 10
作者:  Wu, Tao;  Kwaku, Osafo Raymond;  Li, Hai-Zhou;  Yang, Chong-Ren;  Ge, Long-Jiao;  Xu, Min
Adobe PDF(1069Kb)  |  收藏  |  浏览/下载：159/35  |  提交时间：2019/09/10
ginsengs  ginsenosides  structure-activity relationship  autophagy  
RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 9, 页码: 14
作者:  Guo, Di;  Wang, Yurong;  Wang, Jing;  Song, Lihua;  Wang, Zhe;  Mao, Bingyu;  Tan, Ninghua
Adobe PDF(9639Kb)  |  收藏  |  浏览/下载：134/23  |  提交时间：2019/07/29
RA-XII  lipogenesis  SCAP  SREBP  liver cancer  
Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 79, 页码: 165-176
作者:  Li, Yingying;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Liu, Xingyong;  Zhang, Li;  Wang, Liang-Liang;  Zuo, Zhili
Adobe PDF(7335Kb)  |  收藏  |  浏览/下载：226/25  |  提交时间：2019/07/29
Pharmacophore modeling  Molecular docking  Quantitative structure activity relationship (QSAR)  Molecular dynamics  AMPK  Activator  
Novel dual-color drug screening model for GLUT4 translocation in adipocytes 期刊论文
MOLECULAR AND CELLULAR PROBES, 2019, 卷号: 43, 页码: 6-12
作者:  Lu, Yanting;  Ma, Xiuli;  Kong, Qinghua;  Xu, Yuhui;  Hu, Jing;  Wang, Fang;  Qin, Wanying;  Wang, Libin;  Xiong, Wenyong
Adobe PDF(1287Kb)  |  收藏  |  浏览/下载：212/49  |  提交时间：2019/03/18
GLUT4  pHluorin  Screening  Glucose uptake  
The Effects of Age and Reproduction on the Lipidome of Caenorhabditis elegans 期刊论文
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2019, 页码: 14
作者:  Wan, Qin-Li;  Yang, Zhong-Lin;  Zhou, Xiao-Gang;  Ding, Ai-Jun;  Pu, Yuan-Zhu;  Luo, Huai-Rong;  Wu, Gui-Sheng
Adobe PDF(2720Kb)  |  收藏  |  浏览/下载：153/19  |  提交时间：2019/07/29
12th全国天然有机化学学术会议摘要集 会议录
会议录编者:  中国化学会
Adobe PDF(123481Kb)  |  收藏  |  浏览/下载：169/8  |  提交时间：2018/10/24
Phenolic Compounds from Belamcanda chinensis Seeds 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3, 页码: 580
作者:  Song, Ying-Ying;  Liu, Ying;  Yan, Yong-Ming;  Lu, Xi-Feng;  Cheng, Yong-Xian
Adobe PDF(1350Kb)  |  收藏  |  浏览/下载：162/45  |  提交时间：2018/07/02
Belamcanda Chinensis  Belamcanosides a And b  Gc Analysis  Hmgcr  Sqle  Ldlr  Sort1  
Mechanistic insights into GLUT1 activation and clustering revealed by super-resolution imaging 期刊论文
pnas, 2018, 页码: 1
作者:  Qiuyan Yan;  Yanting Lu;  Lulu Zhou;  Junling Chen;  Haijiao Xu;  Mingjun Cai;  Yan Sh;  Junguang Jiang;  Wenyong Xiong;  Jing Gao;  Hongda Wang
Adobe PDF(2187Kb)  |  收藏  |  浏览/下载：152/34  |  提交时间：2018/06/20