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Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载:250/58  |  提交时间:2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
Adobe PDF(5724Kb)  |  收藏  |  浏览/下载:371/41  |  提交时间:2017/12/18
Synthesis and antitumor activity of novel per-butyrylated glycosides of podophyllotoxin and its derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 7, 页码: 1437-1446
作者:  Zi, Cheng-Ting;  Yang, Dan;  Dong, Fa-Wu;  Li, Gen-Tao;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Hu, Jiang-Miao;  Jiang,ZH (reprint author),Yunnan Univ,Key Lab Med Chem Nat Resource,Kunming 650091,Peoples R China.;  zjiang@lakeheadu.ca;  hujiangmiao@mail.kib.ac.cn
Adobe PDF(842Kb)  |  收藏  |  浏览/下载:311/84  |  提交时间:2015/06/29
Podophyllotoxin  Epipodophyllotoxin  4 '-demethylepipodophyllotoxin  Butyrylated Glycosides  Antitumor  Cytotoxic  Synthesis  
Galiellalactone analogs and their possible precursors from Sarcosomataceae 期刊论文
FITOTERAPIA, 2015, 卷号: 101, 页码: 92-98
作者:  Tian, Jie-Feng;  Yu, Ru-Jian;  Li, Xiao-Xia;  Gao, Hao;  Guo, Liang-Dong;  Li, Yan;  Li, Jia;  Tang, Jin-Shan;  Yao, Xin-Sheng;  Tang,JS (reprint author),Jinan Univ,Inst Tradit Chinese Med & Nat Prod,Coll Pharm,601 Huangpu Ave West,Guangzhou 510632,Guangdong,Peoples R China.;  gztangjinshan@126.com;  tyaoxs@jnu.edu.cn
Adobe PDF(571Kb)  |  收藏  |  浏览/下载:228/47  |  提交时间:2015/06/29
Sarcosomataceae  Chemical Constituents  Galiellalactone Analogs  Pregaliellalactone Analogs  Cytotoxicity  
Synthesis and Anticancer Activity of Glucosylated Podophyllotoxin Derivatives Linked via 4 beta-Triazole Rings 期刊论文
MOLECULES, 2013, 卷号: 18, 期号: 11, 页码: 13992-14012
作者:  Zi, Cheng-Ting;  Xu, Feng-Qing;  Li, Gen-Tao;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Hu, Jiang-Miao
Adobe PDF(404Kb)  |  收藏  |  浏览/下载:174/45  |  提交时间:2015/05/13
Podophyllotoxin  4 Beta-triazole Ring  Click Chemistry  Anticancer Activity  
Novel Tricyclic Indeno[5,6-b] furan-imidazole Hybrid Compounds: Design, Synthesis and Antitumor Activity 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2013, 卷号: 10, 期号: 7, 页码: 561-571
作者:  Chen, Wen;  Yang, Li-Juan;  Li, Yan;  Wang, Xue-Quan;  Wang, Shao-Jie;  Wan, Wei-Chao;  Zhang, Hong-Bin;  Yang, Xiao-Dong
Unknown(243Kb)  |  收藏  |  浏览/下载:238/3  |  提交时间:2013/10/16
Hybrid Compound  Imidazole  Synthesis  Indeno[5  Cytotoxic Activity  6-b]Furan  Structure-activity Relationships  
Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-kappa B Activation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 11, 页码: 4749-4757
作者:  Zhao, Yu;  Su, Jia;  Goto, Masuo;  Morris-Natschke, Susan L.;  Li, Yan;  Zhao, Qin-Shi;  Yao, Zhu-Jun;  Lee, Kuo-Hsiung
Adobe PDF(531Kb)  |  收藏  |  浏览/下载:304/64  |  提交时间:2013/10/16
Natural-products  Biological-activity  Cancer-therapy  Paclitaxel  Taxol  Resistance  Drugs  Chemotherapy  Parthenolide  Brevifoliol  
Cytotoxic cycloartane triterpenes from the roots of Cimicifuga heracleifolia 期刊论文
TETRAHEDRON, 2012, 卷号: 68, 期号: 32, 页码: 6521-6527
作者:  Nian, Yin;  Wang, Hai-Yan;  Su, Jia;  Zhou, Lin;  Feng, Gang;  Li, Yan;  Qiu, Ming-Hua
Adobe PDF(524Kb)  |  收藏  |  浏览/下载:748/309  |  提交时间:2012/09/03
Cimicifuga Heracleifolia  Cycloartane Triterpenes  Cytotoxicity  Structure-activity Relationships  
New Compounds from Euphorbia helioscopia and Absolute Configuration Determination by Computational Methods 期刊论文
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2010, 卷号: 31, 期号: 8, 页码: 2211-2214
作者:  He, Jiangbo;  Zhu, Hua-Jie;  Luo, Gui-Fen;  Liu, Guang-Ming;  Chen, Hao;  Li, Yan;  Chen, Shaopeng;  Lu, Xin;  Zhou, Guochun;  Cheng, Yong-Xian
Adobe PDF(435Kb)  |  收藏  |  浏览/下载:276/102  |  提交时间:2012/04/05
Euphorbia Helioscopia  Euphorbiaceae  Lactam  Terpenoids  Quantum Calculations