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Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：302/36  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 11
作者:  Liu, Tangjingjun;  Xia, Lei;  Yao, Yao;  Yan, Chen;  Fan, Yanhua;  Gajendran, Babu;  Yang, Jue;  Li, You-Jun;  Chen, Juan;  Filmus, Jorge;  Spaner, David E.;  Zacksenhaus, Eldad;  Hao, Xiaojiang;  Ben-David, Yaacov
浏览  |  Adobe PDF(2055Kb)  |  收藏  |  浏览/下载：261/36  |  提交时间：2019/04/15
(+/-)-Perforison A, A Pair of New Chromone Enantiomers from Harrisonia perforata 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2017, 卷号: 12, 期号: 1, 页码: 63-65
作者:  Yuan, Wen-Juan;  Gao, Wen-Fen;  Zhang, Jia-Hui;  Cao, Pei;  Zhang, Yu;  Chen, Duo-Zhi;  Li, Shun-Lin;  Di, Ying-Tong;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(954Kb)  |  收藏  |  浏览/下载：404/220  |  提交时间：2017/04/17
Harrisonia Perforata  Simaroubaceae  Chromone  Electronic Circular Dichroism  Perforison a  
Three new diterpenes with cytotoxic activity from the roots of Euphorbia ebracteolata Hayata 期刊论文
PHYTOCHEMISTRY LETTERS, 2016, 卷号: 18, 期号: 1, 页码: 176-179
作者:  Yuan, Wen-Juan;  Yang, Guo-Ping;  Zhang, Jia-Hui;  Zhang, Yu;  Chen, Duo-Zhi;  Li, Shun-Lin;  Di, Ying-Tong;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(558Kb)  |  收藏  |  浏览/下载：463/156  |  提交时间：2017/02/14
Euphorbiaceae  Euphorbia Ebracteolata  Diterpenes  Ebracteolatas A-c  Cytotoxic Activity  
Bioactive Limonoid Constituents of Munronia henryi 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2015, 卷号: 78, 期号: 4, 页码: 811-821
作者:  Yan, Ying;  Zhang, Jian-Xin;  Huang, Tao;  Mao, Xin-Ying;  Gu, Wei;  He, Hong-Ping;  Di, Ying-Tong;  Li, Shun-Lin;  Chen, Duo-Zhi;  Zhang, Yu;  Hao, Xiao-Jiang;  Zhang,Y (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West,Kunming 650201,Yunnan,Peoples R China.;  zhangyu@mail.kib.ac.cn;  haoxj@mail.kib.ac.cn
浏览  |  Adobe PDF(1552Kb)  |  收藏  |  浏览/下载：243/61  |  提交时间：2015/07/20
Limonoids from Aphanamixis polystachya and Their Antifeedant Activity 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2014, 卷号: 77, 期号: 3, 页码: 472-482
作者:  Cai, Jie-Yun;  Chen, Duo-Zhi;  Luo, Shi-Hong;  Kong, Ning-Chuan;  Zhang, Yu;  Di, Ying-Tong;  Zhang, Qiang;  Hua, Juan;  Jing, Shu-Xi;  Li, Shun-Lin;  Li, Sheng-Hong;  Hao, Xiao-Jiang;  He, Hong-Ping
Adobe PDF(477Kb)  |  收藏  |  浏览/下载：397/119  |  提交时间：2014/05/16
Biological-activities  Cipadessa-baccifera  Meliaceae  Tetranortriterpenoids  Sesquiterpenes  Triterpenoids  Prieurianin  Derivatives  Chemistry  Mangrove  
A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2013, 卷号: 63, 期号: SI, 页码: 485-494
作者:  Liu, Jinhua;  Mu, Chenglong;  Yue, Wen;  Li, Jie;  Ma, Biao;  Zhao, Lixia;  Liu, Lei;  Chen, Quan;  Yan, Chen;  Liu, Haiyang;  Hao, Xiaojiang;  Zhu, Yushan
浏览  |  Adobe PDF(2679Kb)  |  收藏  |  浏览/下载：298/58  |  提交时间：2013/10/16
Thioredoxin Reductase  Bim  Ros  Apoptosis  Cancer  
Cytotoxic Limonoids from Melia azedarach 期刊论文
PLANTA MEDICA, 2013, 卷号: 79, 期号: 2, 页码: 163-168
作者:  Yuan, Chun-Mao;  Zhang, Yu;  Tang, Gui-Hua;  Li, Yan;  He, Hong-Ping;  Li, Shi-Fei;  Hou, Li;  Li, Xing-Yao;  Di, Ying-Tong;  Li, Shun-Lin;  Hua, Hui-Ming;  Hao, Xiao-Jiang
Adobe PDF(134Kb)  |  收藏  |  浏览/下载：583/295  |  提交时间：2013/03/18
Melia Azedarach Linn  Meliaceae  Limonoids  Chemical Constituents  Cytotoxicities  
A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/beta-catenin signaling and colon cancer cell tumorigenesis 期刊论文
CELL RESEARCH, 2011, 卷号: 21, 期号: 5, 页码: 730-740
作者:  Wang, Wei;  Liu, Haiyang;  Wang, Sheng;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(1539Kb)  |  收藏  |  浏览/下载：269/32  |  提交时间：2012/07/25
Wnt  Small Molecule  Inhibitor  Tumorigenesis