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Discovery of novel modulators targeting human TRPC5: Docking-based virtual screening, molecular dynamics simulation and binding af fi nity predication 期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2021, 卷号: 102, 页码: 107795
Authors:  Liu,Bin;  Zhang,Wei;  Guo,Sheng;  Zuo,Zhili
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hTRPC5  Homology modeling  Molecular docking  Molecular dynamics simulation  Virtual screening  INHIBITOR  CHANNELS  GROMACS  POTENT  AMBER  IDENTIFICATION  CONSTRAINTS  INTEGRATION  AMYGDALA  
Identification of Novel TRPC5 Inhibitors by Pharmacophore-Based and Structure-Based Approaches 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2020
Authors:  Li, Shuxiang;  Zhang, Shuqun;  Chen, Dingyuan;  Jiang, Xuan;  Liu, Bin;  Zhang, Hongbin;  Rachakunta, Munikishore;  Zuo, Zhili
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M084抗衰老机制及WWP-1调控脂代谢与衰老机制的研究 学位论文
: 中国科学院大学, 2017
Authors:  丁爱军
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Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way 期刊论文
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2017, 卷号: 426, 期号: 1-2, 页码: 101-109
Authors:  Ding, Ai-Jun;  Wu, Gui-Sheng;  Tang, Bin;  Hong, Xuechuan;  Zhu, Michael X.;  Luo, Huai-Rong
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Aging  Benzimidazole Derivative M084  Caenorhabditis Elegans  Lifespan  
Current Perspective in the Discovery of Anti-aging Agents from Natural Products. 期刊论文
Natural products and bioprospecting, 2017, 卷号: 7, 期号: 5, 页码: 335-404
Authors:  Ding, Ai-Jun;  Zheng, Shan-Qing;  Huang, Xiao-Bing;  Xing, Ti-Kun;  Wu, Gui-Sheng;  Sun, Hua-Ying;  Qi, Shu-Hua;  Luo, Huai-Rong
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2017年中科院昆明植物研究所年报 其他
2017-01-01
Authors:  昆明植物所
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小鼠海马下托腹侧向全脑的顺向投射研究 学位论文
: 中国科学院大学, 2016
Authors:  唐贺
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Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 8
Authors:  Yang, Li-Ping;  Jiang, Fang-Jie;  Wu, Gui-Sheng;  Deng, Ke;  Wen, Meng;  Zhou, Xiaoju;  Hong, Xuechuan;  Zhu, Michael X.;  Luo, Huai-Rong
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Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2015, 卷号: 172, 期号: 14, 页码: 3495-3509
Authors:  Zhu, Yingmin;  Lu, Yungang;  Qu, Chunrong;  Miller, Melissa;  Tian, Jinbin;  Thakur, Dhananjay P.;  Zhu, Jinmei;  Deng, Zixin;  Hu, Xianming;  Wu, Meng;  McManus, Owen B.;  Li, Min;  Hong, Xuechuan;  Zhu, Michael X.;  Luo, Huai-Rong
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TRPC4/C5抑制剂M084抗抑郁作用及机制研究 学位论文
, 昆明: 中国科学院大学, 2015
Authors:  杨丽萍
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抗抑郁  Trpc4/c5  Bdnf  情绪相关疾病  M084